PSAC_THEVB
ID PSAC_THEVB Reviewed; 81 AA.
AC P0A415; P18083; P20451;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Photosystem I iron-sulfur center;
DE EC=1.97.1.12;
DE AltName: Full=9 kDa polypeptide;
DE AltName: Full=PSI-C;
DE AltName: Full=Photosystem I subunit VII;
DE AltName: Full=PsaC;
GN Name=psaC; OrderedLocusNames=tsl1013;
OS Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC Bacteria; Cyanobacteria; Pseudanabaenales; Thermosynechococcaceae;
OC Thermosynechococcus.
OX NCBI_TaxID=197221;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2133 / IAM M-273 / BP-1;
RX PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA Takeuchi C., Yamada M., Tabata S.;
RT "Complete genome structure of the thermophilic cyanobacterium
RT Thermosynechococcus elongatus BP-1.";
RL DNA Res. 9:123-130(2002).
RN [2]
RP REVIEW.
RX PubMed=11687205; DOI=10.1016/s0005-2728(01)00195-5;
RA Fromme P., Jordan P., Krauss N.;
RT "Structure of photosystem I.";
RL Biochim. Biophys. Acta 1507:5-31(2001).
RN [3]
RP X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS), SUBUNIT, AND SUBCELLULAR LOCATION.
RX PubMed=8901876; DOI=10.1038/nsb1196-965;
RA Krauss N., Schubert W.-D., Klukas O., Fromme P., Witt H.T., Saenger W.;
RT "Photosystem I at 4-A resolution represents the first structural model of a
RT joint photosynthetic reaction centre and core antenna system.";
RL Nat. Struct. Biol. 3:965-973(1996).
RN [4]
RP X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS), SUBUNIT, AND SUBCELLULAR LOCATION.
RX PubMed=10066799; DOI=10.1074/jbc.274.11.7351;
RA Klukas O., Schubert W.-D., Jordan P., Krauss N., Fromme P., Witt H.T.,
RA Saenger W.;
RT "Photosystem I, an improved model of the stromal subunits PsaC, PsaD, and
RT PsaE.";
RL J. Biol. Chem. 274:7351-7360(1999).
RN [5]
RP X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 2-81 IN COMPLEX WITH 4FE-4S
RP CLUSTER, COFACTOR, SUBUNIT, AND SUBCELLULAR LOCATION.
RX PubMed=11418848; DOI=10.1038/35082000;
RA Jordan P., Fromme P., Witt H.T., Klukas O., Saenger W., Krauss N.;
RT "Three-dimensional structure of cyanobacterial photosystem I at 2.5 A
RT resolution.";
RL Nature 411:909-917(2001).
CC -!- FUNCTION: Apoprotein for the two 4Fe-4S centers FA and FB of
CC photosystem I (PSI); essential for photochemical activity. FB is the
CC terminal electron acceptor of PSI, donating electrons to ferredoxin.
CC The C-terminus interacts with PsaA/B/D and helps assemble the protein
CC into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI
CC is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting
CC photonic excitation into a charge separation, which transfers an
CC electron from the donor P700 chlorophyll pair to the spectroscopically
CC characterized acceptors A0, A1, FX, FA and FB in turn.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=hnu + oxidized [2Fe-2S]-[ferredoxin] + reduced [plastocyanin]
CC = oxidized [plastocyanin] + reduced [2Fe-2S]-[ferredoxin];
CC Xref=Rhea:RHEA:30407, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC Rhea:RHEA-COMP:10039, Rhea:RHEA-COMP:10040, ChEBI:CHEBI:29036,
CC ChEBI:CHEBI:30212, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738,
CC ChEBI:CHEBI:49552; EC=1.97.1.12;
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000269|PubMed:11418848};
CC Note=Binds 2 [4Fe-4S] clusters. Cluster 2 is most probably the
CC spectroscopically characterized electron acceptor FA and cluster 1 is
CC most probably FB. {ECO:0000305|PubMed:11418848};
CC -!- SUBUNIT: The cyanobacterial PSI reaction center is composed of one copy
CC each of PsaA,B,C,D,E,F,I,J,K,L,M and X, and forms trimeric complexes.
CC {ECO:0000269|PubMed:10066799, ECO:0000269|PubMed:11418848,
CC ECO:0000269|PubMed:8901876}.
CC -!- SUBCELLULAR LOCATION: Cellular thylakoid membrane
CC {ECO:0000269|PubMed:10066799, ECO:0000269|PubMed:11418848,
CC ECO:0000269|PubMed:8901876}; Peripheral membrane protein
CC {ECO:0000269|PubMed:11418848}; Cytoplasmic side
CC {ECO:0000269|PubMed:11418848}.
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DR EMBL; BA000039; BAC08565.1; -; Genomic_DNA.
DR RefSeq; NP_681803.1; NC_004113.1.
DR RefSeq; WP_011056855.1; NC_004113.1.
DR PDB; 1C51; X-ray; 4.00 A; -.
DR PDB; 1JB0; X-ray; 2.50 A; C=2-81.
DR PDB; 2PPS; X-ray; 4.00 A; -.
DR PDB; 3PCQ; X-ray; 8.98 A; C=2-81.
DR PDB; 4FE1; X-ray; 4.92 A; C=2-81.
DR PDB; 5ZF0; X-ray; 4.20 A; C1/C2/C3/C4/C5/C6=2-81.
DR PDB; 6LU1; EM; 3.20 A; C=1-81.
DR PDB; 6PFY; X-ray; 2.90 A; C/N/a=1-81.
DR PDB; 6PGK; X-ray; 2.90 A; C/N/a=1-81.
DR PDB; 6TRA; EM; 2.85 A; C=1-81.
DR PDB; 6TRC; EM; 2.98 A; 3/C/c=1-81.
DR PDB; 6TRD; EM; 3.16 A; 3/C/c=1-81.
DR PDB; 7BW2; X-ray; 6.50 A; C=1-81.
DR PDB; 7M75; X-ray; 2.75 A; C=2-81.
DR PDB; 7M76; X-ray; 3.00 A; C=2-81.
DR PDB; 7M78; X-ray; 3.00 A; C=2-81.
DR PDBsum; 1C51; -.
DR PDBsum; 1JB0; -.
DR PDBsum; 2PPS; -.
DR PDBsum; 3PCQ; -.
DR PDBsum; 4FE1; -.
DR PDBsum; 5ZF0; -.
DR PDBsum; 6LU1; -.
DR PDBsum; 6PFY; -.
DR PDBsum; 6PGK; -.
DR PDBsum; 6TRA; -.
DR PDBsum; 6TRC; -.
DR PDBsum; 6TRD; -.
DR PDBsum; 7BW2; -.
DR PDBsum; 7M75; -.
DR PDBsum; 7M76; -.
DR PDBsum; 7M78; -.
DR AlphaFoldDB; P0A415; -.
DR SMR; P0A415; -.
DR IntAct; P0A415; 1.
DR STRING; 197221.22294736; -.
DR EnsemblBacteria; BAC08565; BAC08565; BAC08565.
DR KEGG; tel:tsl1013; -.
DR PATRIC; fig|197221.4.peg.1063; -.
DR eggNOG; COG1143; Bacteria.
DR OMA; GHMSHAV; -.
DR OrthoDB; 1873445at2; -.
DR BRENDA; 1.97.1.12; 7763.
DR EvolutionaryTrace; P0A415; -.
DR Proteomes; UP000000440; Chromosome.
DR GO; GO:0009522; C:photosystem I; IEA:UniProtKB-KW.
DR GO; GO:0031676; C:plasma membrane-derived thylakoid membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009773; P:photosynthetic electron transport in photosystem I; IEA:InterPro.
DR HAMAP; MF_01303; PSI_PsaC; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR017491; PSI_PsaC.
DR Pfam; PF12838; Fer4_7; 1.
DR TIGRFAMs; TIGR03048; PS_I_psaC; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 1: Evidence at protein level;
KW 3D-structure; 4Fe-4S; Electron transport; Iron; Iron-sulfur; Membrane;
KW Metal-binding; Oxidoreductase; Photosynthesis; Photosystem I;
KW Reference proteome; Repeat; Thylakoid; Transport.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..81
FT /note="Photosystem I iron-sulfur center"
FT /id="PRO_0000062018"
FT DOMAIN 2..31
FT /note="4Fe-4S ferredoxin-type 1"
FT DOMAIN 37..68
FT /note="4Fe-4S ferredoxin-type 2"
FT BINDING 11
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000269|PubMed:11418848"
FT BINDING 14
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000269|PubMed:11418848"
FT BINDING 17
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000269|PubMed:11418848"
FT BINDING 21
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000269|PubMed:11418848"
FT BINDING 48
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000269|PubMed:11418848"
FT BINDING 51
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000269|PubMed:11418848"
FT BINDING 54
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000269|PubMed:11418848"
FT BINDING 58
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000269|PubMed:11418848"
FT STRAND 4..8
FT /evidence="ECO:0007829|PDB:1JB0"
FT HELIX 16..20
FT /evidence="ECO:0007829|PDB:1JB0"
FT STRAND 27..30
FT /evidence="ECO:0007829|PDB:1JB0"
FT STRAND 32..34
FT /evidence="ECO:0007829|PDB:1JB0"
FT STRAND 37..41
FT /evidence="ECO:0007829|PDB:1JB0"
FT HELIX 45..47
FT /evidence="ECO:0007829|PDB:1JB0"
FT HELIX 53..57
FT /evidence="ECO:0007829|PDB:1JB0"
FT STRAND 60..62
FT /evidence="ECO:0007829|PDB:1JB0"
FT STRAND 64..68
FT /evidence="ECO:0007829|PDB:1JB0"
FT TURN 74..78
FT /evidence="ECO:0007829|PDB:1JB0"
SQ SEQUENCE 81 AA; 8800 MW; ED5362F4D6E48F36 CRC64;
MAHTVKIYDT CIGCTQCVRA CPTDVLEMVP WDGCKAGQIA SSPRTEDCVG CKRCETACPT
DFLSIRVYLG AETTRSMGLA Y
