ID   PSB3_ONCMY              Reviewed;         205 AA.
AC   O73817;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Proteasome subunit beta type-3;
DE   AltName: Full=Proteasome chain 13;
DE   AltName: Full=Proteasome component C10-II;
DE   AltName: Full=Proteasome theta chain;
GN   Name=psmb3;
OS   Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC   Salmonidae; Salmoninae; Oncorhynchus.
OX   NCBI_TaxID=8022;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Martin S.A.M.;
RT   "Isolation of a rainbow trout (Oncorhynchus mykiss) proteasome cDNA.";
RL   Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Non-catalytic component of the proteasome, a multicatalytic
CC       proteinase complex which is characterized by its ability to cleave
CC       peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group
CC       at neutral or slightly basic pH. The proteasome has an ATP-dependent
CC       proteolytic activity.
CC   -!- SUBUNIT: The 26S proteasome consists of a 20S proteasome core and two
CC       19S regulatory subunits. The 20S proteasome core is composed of 28
CC       subunits that are arranged in four stacked rings, resulting in a
CC       barrel-shaped structure. The two end rings are each formed by seven
CC       alpha subunits, and the two central rings are each formed by seven beta
CC       subunits. The catalytic chamber with the active sites is on the inside
CC       of the barrel (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
CC   -!- SIMILARITY: Belongs to the peptidase T1B family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00809}.
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DR   EMBL; AF058707; AAC14141.1; -; mRNA.
DR   RefSeq; NP_001117722.1; NM_001124250.1.
DR   AlphaFoldDB; O73817; -.
DR   SMR; O73817; -.
DR   MEROPS; T01.983; -.
DR   Ensembl; ENSOMYT00000017360; ENSOMYP00000015730; ENSOMYG00000007720.
DR   GeneID; 100135869; -.
DR   KEGG; omy:100135869; -.
DR   GeneTree; ENSGT00550000074820; -.
DR   OrthoDB; 1170036at2759; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005839; C:proteasome core complex; ISS:UniProtKB.
DR   GO; GO:0019774; C:proteasome core complex, beta-subunit complex; ISS:UniProtKB.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   CDD; cd03759; proteasome_beta_type_3; 1.
DR   Gene3D; 3.60.20.10; -; 1.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   InterPro; IPR033811; Proteasome_beta_3.
DR   InterPro; IPR016050; Proteasome_bsu_CS.
DR   InterPro; IPR001353; Proteasome_sua/b.
DR   InterPro; IPR023333; Proteasome_suB-type.
DR   PANTHER; PTHR11599:SF62; PTHR11599:SF62; 1.
DR   Pfam; PF00227; Proteasome; 1.
DR   SUPFAM; SSF56235; SSF56235; 1.
DR   PROSITE; PS00854; PROTEASOME_BETA_1; 1.
DR   PROSITE; PS51476; PROTEASOME_BETA_2; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Proteasome.
FT   CHAIN           1..205
FT                   /note="Proteasome subunit beta type-3"
FT                   /id="PRO_0000148060"
SQ   SEQUENCE   205 AA;  23021 MW;  E0177236217DD0D3 CRC64;
     MSIMSYNGGA VMAMKGKQCV AIAADRRFGV QAQMVTTDFQ KIFPMGDRLY IGLAGLATDV
     QTVSQRLKFR LNLYELKEGR QIKPKTFMSM VSNLLYERRF GPYYIEPVIA GLDPKTFEPF
     ICSLDLIGCP MVTEDFVVSG TCSEQMYGMC ESLWEPDMEP EDLFETISQA MLNAVDRDAV
     SGMGVVVQVI EKDKITTRTL KARMD