PSB3_YEAST
ID PSB3_YEAST Reviewed; 205 AA.
AC P25451; D3DM02;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1992, sequence version 1.
DT 03-AUG-2022, entry version 214.
DE RecName: Full=Proteasome subunit beta type-3;
DE AltName: Full=Macropain subunit PUP3;
DE AltName: Full=Multicatalytic endopeptidase complex subunit PUP3;
DE AltName: Full=Proteasome component PUP3;
GN Name=PUP3; OrderedLocusNames=YER094C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1620128; DOI=10.1128/mcb.12.7.3235-3246.1992;
RA Basile G.M., Aker M., Mortimer R.K.;
RT "Nucleotide sequence and transcriptional regulation of the yeast
RT recombinational repair gene RAD51.";
RL Mol. Cell. Biol. 12:3235-3246(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169868;
RA Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA Botstein D., Davis R.W.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL Nature 387:78-81(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-31, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT "A multidimensional chromatography technology for in-depth phosphoproteome
RT analysis.";
RL Mol. Cell. Proteomics 7:1389-1396(2008).
RN [5]
RP UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-70, AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22106047; DOI=10.1002/pmic.201100166;
RA Starita L.M., Lo R.S., Eng J.K., von Haller P.D., Fields S.;
RT "Sites of ubiquitin attachment in Saccharomyces cerevisiae.";
RL Proteomics 12:236-240(2012).
RN [6]
RP X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF COMPLEX WITH THE 20S PROTEASOME.
RX PubMed=9087403; DOI=10.1038/386463a0;
RA Groll M., Ditzel L., Loewe J., Stock D., Bochtler M., Bartunik H.D.,
RA Huber R.;
RT "Structure of 20S proteasome from yeast at 2.4-A resolution.";
RL Nature 386:463-471(1997).
RN [7]
RP X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF COMPLEX WITH THE 20S PROTEASOME
RP AND A 11S REGULATORY COMPLEX.
RX PubMed=11081519; DOI=10.1038/35040607;
RA Whitby F.G., Masters E.I., Kramer L., Knowlton J.R., Yao Y., Wang C.C.,
RA Hill C.P.;
RT "Structural basis for the activation of 20S proteasomes by 11S
RT regulators.";
RL Nature 408:115-120(2000).
RN [8]
RP X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF COMPLEX WITH THE 20S PROTEASOME.
RX PubMed=11062564; DOI=10.1038/80992;
RA Groll M., Bajorek M., Koehler A., Moroder L., Rubin D.M., Huber R.,
RA Glickman M.H., Finley D.;
RT "A gated channel into the proteasome core particle.";
RL Nat. Struct. Biol. 7:1062-1067(2000).
RN [9]
RP X-RAY CRYSTALLOGRAPHY (2.81 ANGSTROMS) OF COMPLEX WITH THE 20S PROTEASOME
RP AND A TMC-95-BASED INHIBITOR.
RX PubMed=16793518; DOI=10.1016/j.chembiol.2006.04.005;
RA Groll M., Goetz M., Kaiser M., Weyher E., Moroder L.;
RT "TMC-95-based inhibitor design provides evidence for the catalytic
RT versatility of the proteasome.";
RL Chem. Biol. 13:607-614(2006).
RN [10]
RP X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF COMPLEX WITH THE 20S PROTEASOME
RP AND SALINOSPORAMIDE.
RX PubMed=16608349; DOI=10.1021/ja058320b;
RA Groll M., Huber R., Potts B.C.M.;
RT "Crystal structures of salinosporamide A (NPI-0052) and B (NPI-0047) in
RT complex with the 20S proteasome reveal important consequences of beta-
RT lactone ring opening and a mechanism for irreversible binding.";
RL J. Am. Chem. Soc. 128:5136-5141(2006).
RN [11]
RP X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF COMPLEX WITH THE 20S PROTEASOME
RP AND BORTEZOMIB.
RX PubMed=16531229; DOI=10.1016/j.str.2005.11.019;
RA Groll M., Berkers C.R., Ploegh H.L., Ovaa H.;
RT "Crystal structure of the boronic acid-based proteasome inhibitor
RT bortezomib in complex with the yeast 20S proteasome.";
RL Structure 14:451-456(2006).
RN [12]
RP X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 2-205 IN COMPLEX WITH THE
RP PROTEASOME.
RX PubMed=20227375; DOI=10.1016/j.molcel.2010.02.002;
RA Sadre-Bazzaz K., Whitby F.G., Robinson H., Formosa T., Hill C.P.;
RT "Structure of a Blm10 complex reveals common mechanisms for proteasome
RT binding and gate opening.";
RL Mol. Cell 37:728-735(2010).
RN [13]
RP STRUCTURE BY ELECTRON MICROSCOPY (7.4 ANGSTROMS) OF THE 26S PROTEASOME.
RX PubMed=22927375; DOI=10.1073/pnas.1213333109;
RA Beck F., Unverdorben P., Bohn S., Schweitzer A., Pfeifer G., Sakata E.,
RA Nickell S., Plitzko J.M., Villa E., Baumeister W., Forster F.;
RT "Near-atomic resolution structural model of the yeast 26S proteasome.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:14870-14875(2012).
CC -!- FUNCTION: Non-catalytic component of the proteasome which degrades
CC poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is
CC essential for the regulated turnover of proteins and for the removal of
CC misfolded proteins. The proteasome is a multicatalytic proteinase
CC complex that is characterized by its ability to cleave peptides with
CC Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or
CC slightly basic pH. It has an ATP-dependent proteolytic activity. This
CC subunit may participate in the trypsin-like activity of the enzyme
CC complex.
CC -!- SUBUNIT: The 26S proteasome consists of a 20S proteasome core and two
CC 19S regulatory subunits. The 20S proteasome core is composed of 28
CC subunits that are arranged in four stacked rings, resulting in a
CC barrel-shaped structure. The two end rings are each formed by seven
CC alpha subunits, and the two central rings are each formed by seven beta
CC subunits. The catalytic chamber with the active sites is on the inside
CC of the barrel. {ECO:0000269|PubMed:20227375}.
CC -!- INTERACTION:
CC P25451; P25043: PUP1; NbExp=3; IntAct=EBI-13993, EBI-14009;
CC -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
CC -!- SIMILARITY: Belongs to the peptidase T1B family. {ECO:0000255|PROSITE-
CC ProRule:PRU00809}.
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DR EMBL; M88470; AAA34946.1; -; Genomic_DNA.
DR EMBL; U18839; AAB64649.1; -; Genomic_DNA.
DR EMBL; BK006939; DAA07756.1; -; Genomic_DNA.
DR PIR; S29251; S29251.
DR RefSeq; NP_011020.3; NM_001178985.3.
DR PDB; 1FNT; X-ray; 3.20 A; J/X=1-205.
DR PDB; 1G0U; X-ray; 2.40 A; I/W=1-205.
DR PDB; 1G65; X-ray; 2.25 A; I/W=2-205.
DR PDB; 1JD2; X-ray; 3.00 A; I/P=2-205.
DR PDB; 1RYP; X-ray; 1.90 A; J/X=2-205.
DR PDB; 1Z7Q; X-ray; 3.22 A; J/X=1-205.
DR PDB; 2F16; X-ray; 2.80 A; I/W=2-205.
DR PDB; 2FAK; X-ray; 2.80 A; I/W=2-205.
DR PDB; 2GPL; X-ray; 2.81 A; I/W=2-205.
DR PDB; 2ZCY; X-ray; 2.90 A; I/W=1-205.
DR PDB; 3BDM; X-ray; 2.70 A; I/W=1-205.
DR PDB; 3D29; X-ray; 2.60 A; I/W=2-205.
DR PDB; 3DY3; X-ray; 2.81 A; I/W=2-205.
DR PDB; 3DY4; X-ray; 2.80 A; I/W=2-205.
DR PDB; 3E47; X-ray; 3.00 A; I/W=2-205.
DR PDB; 3GPJ; X-ray; 2.70 A; I/W=2-205.
DR PDB; 3GPT; X-ray; 2.41 A; I/W=2-205.
DR PDB; 3GPW; X-ray; 2.50 A; I/W=2-205.
DR PDB; 3HYE; X-ray; 2.50 A; I/W=2-205.
DR PDB; 3JCO; EM; 4.80 A; 5/j=1-205.
DR PDB; 3JCP; EM; 4.60 A; 5/j=1-205.
DR PDB; 3MG0; X-ray; 2.68 A; I/W=2-205.
DR PDB; 3MG4; X-ray; 3.11 A; I/W=2-205.
DR PDB; 3MG6; X-ray; 2.60 A; I/W=1-205.
DR PDB; 3MG7; X-ray; 2.78 A; I/W=1-205.
DR PDB; 3MG8; X-ray; 2.59 A; I/W=1-205.
DR PDB; 3NZJ; X-ray; 2.40 A; I/W=1-205.
DR PDB; 3NZW; X-ray; 2.50 A; I/W=1-205.
DR PDB; 3NZX; X-ray; 2.70 A; I/W=1-205.
DR PDB; 3OEU; X-ray; 2.60 A; I/W=2-205.
DR PDB; 3OEV; X-ray; 2.85 A; I/W=2-205.
DR PDB; 3OKJ; X-ray; 2.70 A; I/W=2-205.
DR PDB; 3SDI; X-ray; 2.65 A; I/W=2-205.
DR PDB; 3SDK; X-ray; 2.70 A; I/W=2-205.
DR PDB; 3SHJ; X-ray; 2.80 A; I/W=2-205.
DR PDB; 3TDD; X-ray; 2.70 A; I/W=2-205.
DR PDB; 3UN4; X-ray; 3.40 A; I/W=1-205.
DR PDB; 3UN8; X-ray; 2.70 A; I/W=1-205.
DR PDB; 3WXR; X-ray; 3.15 A; J/X=1-205.
DR PDB; 4CR2; EM; 7.70 A; 3=1-205.
DR PDB; 4CR3; EM; 9.30 A; 3=1-205.
DR PDB; 4CR4; EM; 8.80 A; 3=1-205.
DR PDB; 4EU2; X-ray; 2.51 A; J/X=2-205.
DR PDB; 4FZC; X-ray; 2.80 A; I/W=2-205.
DR PDB; 4FZG; X-ray; 3.00 A; I/W=2-205.
DR PDB; 4G4S; X-ray; 2.49 A; J=1-205.
DR PDB; 4GK7; X-ray; 2.80 A; I/W=2-205.
DR PDB; 4HNP; X-ray; 2.80 A; I/W=2-205.
DR PDB; 4HRC; X-ray; 2.80 A; I/W=2-205.
DR PDB; 4HRD; X-ray; 2.80 A; I/W=2-205.
DR PDB; 4INR; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4INT; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4INU; X-ray; 3.10 A; I/W=1-205.
DR PDB; 4J70; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4JSQ; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4JSU; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4JT0; X-ray; 3.10 A; I/W=1-205.
DR PDB; 4LQI; X-ray; 2.70 A; I/W=2-205.
DR PDB; 4LTC; X-ray; 2.50 A; I/W=1-205.
DR PDB; 4NNN; X-ray; 2.50 A; I/W=1-205.
DR PDB; 4NNW; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4NO1; X-ray; 2.50 A; I/W=1-205.
DR PDB; 4NO6; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4NO8; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4NO9; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4Q1S; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4QBY; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QLQ; X-ray; 2.40 A; I/W=1-205.
DR PDB; 4QLS; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QLT; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QLU; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QLV; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4QUX; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QUY; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QV0; X-ray; 3.10 A; I/W=1-205.
DR PDB; 4QV1; X-ray; 2.50 A; I/W=1-205.
DR PDB; 4QV3; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QV4; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4QV5; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4QV6; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QV7; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4QV8; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4QV9; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4QVL; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QVM; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QVN; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4QVP; X-ray; 2.30 A; I/W=1-205.
DR PDB; 4QVQ; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4QVV; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QVW; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QVY; X-ray; 2.51 A; I/W=1-205.
DR PDB; 4QW0; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4QW1; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4QW3; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4QW4; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QW5; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QW6; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4QW7; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4QWF; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QWG; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4QWI; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4QWJ; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4QWK; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QWL; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4QWR; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4QWS; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QWU; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QWX; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4QXJ; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QZ0; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QZ1; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QZ2; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4QZ3; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QZ4; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QZ5; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QZ6; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4QZ7; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4QZW; X-ray; 3.00 A; I/W=1-205.
DR PDB; 4QZX; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4QZZ; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4R00; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4R02; X-ray; 2.50 A; I/W=1-205.
DR PDB; 4R17; X-ray; 2.10 A; I/W=1-205.
DR PDB; 4R18; X-ray; 2.40 A; I/W=1-205.
DR PDB; 4RUR; X-ray; 2.50 A; I/W=1-205.
DR PDB; 4V7O; X-ray; 3.00 A; AN/AZ/BJ/BX=2-205.
DR PDB; 4X6Z; X-ray; 2.70 A; J/X=1-205.
DR PDB; 4Y69; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4Y6A; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4Y6V; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4Y6Z; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4Y70; X-ray; 2.40 A; I/W=1-205.
DR PDB; 4Y74; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4Y75; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4Y77; X-ray; 2.50 A; I/W=1-205.
DR PDB; 4Y78; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4Y7W; X-ray; 2.50 A; I/W=1-205.
DR PDB; 4Y7X; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4Y7Y; X-ray; 2.40 A; I/W=1-205.
DR PDB; 4Y80; X-ray; 2.50 A; I/W=1-205.
DR PDB; 4Y81; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4Y82; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4Y84; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4Y8G; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4Y8H; X-ray; 2.50 A; I/W=1-205.
DR PDB; 4Y8I; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4Y8J; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4Y8K; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4Y8L; X-ray; 2.40 A; I/W=1-205.
DR PDB; 4Y8M; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4Y8N; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4Y8O; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4Y8P; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4Y8Q; X-ray; 2.60 A; I/W=1-205.
DR PDB; 4Y8R; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4Y8S; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4Y8T; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4Y8U; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4Y9Y; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4Y9Z; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4YA0; X-ray; 2.80 A; I/W=1-205.
DR PDB; 4YA1; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4YA2; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4YA3; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4YA4; X-ray; 2.90 A; I/W=1-205.
DR PDB; 4YA5; X-ray; 2.50 A; I/W=1-205.
DR PDB; 4YA7; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4YA9; X-ray; 2.70 A; I/W=1-205.
DR PDB; 4Z1L; X-ray; 3.00 A; I/W=1-205.
DR PDB; 5A5B; EM; 9.50 A; 3=1-205.
DR PDB; 5AHJ; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5BOU; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5BXL; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5BXN; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5CGF; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5CGG; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5CGH; X-ray; 2.50 A; I/W=1-205.
DR PDB; 5CGI; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5CZ4; X-ray; 2.30 A; I/W=1-205.
DR PDB; 5CZ5; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5CZ6; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5CZ7; X-ray; 2.50 A; I/W=1-205.
DR PDB; 5CZ8; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5CZ9; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5CZA; X-ray; 2.50 A; I/W=1-205.
DR PDB; 5D0S; X-ray; 2.50 A; I/W=1-205.
DR PDB; 5D0T; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5D0V; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5D0W; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5D0X; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5D0Z; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5DKI; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5DKJ; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5FG7; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5FG9; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5FGA; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5FGD; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5FGE; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5FGF; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5FGG; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5FGH; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5FGI; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5FHS; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5JHR; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5JHS; X-ray; 3.00 A; I/W=1-205.
DR PDB; 5L52; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5L54; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5L55; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5L5A; X-ray; 2.40 A; I/W=1-205.
DR PDB; 5L5B; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5L5D; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5L5E; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5L5F; X-ray; 2.50 A; I/W=1-205.
DR PDB; 5L5H; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5L5I; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5L5J; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5L5O; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5L5P; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5L5Q; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5L5R; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5L5S; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5L5T; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5L5U; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5L5V; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5L5W; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5L5X; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5L5Y; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5L5Z; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5L60; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5L61; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5L62; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5L63; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5L64; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5L65; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5L66; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5L67; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5L68; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5L69; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5L6A; X-ray; 2.80 A; I/W=1-205.
DR PDB; 5L6B; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5L6C; X-ray; 2.60 A; I/W=1-205.
DR PDB; 5LAI; X-ray; 2.50 A; I/W=1-205.
DR PDB; 5LAJ; X-ray; 2.90 A; I/W=1-205.
DR PDB; 5LTT; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5M2B; X-ray; 2.70 A; I/W=1-205.
DR PDB; 5MP9; EM; 4.10 A; 3/j=1-205.
DR PDB; 5MPA; EM; 4.50 A; 3/j=1-205.
DR PDB; 5MPB; EM; 7.80 A; 3/j=1-205.
DR PDB; 5MPC; EM; 7.70 A; 3/j=1-205.
DR PDB; 5NIF; X-ray; 3.00 A; J/X=1-205.
DR PDB; 5WVI; EM; 6.30 A; 3/h=1-205.
DR PDB; 5WVK; EM; 4.20 A; 3/h=1-205.
DR PDB; 6EF3; EM; 4.17 A; 3=1-205.
DR PDB; 6FVT; EM; 4.10 A; 3/j=2-205.
DR PDB; 6FVU; EM; 4.50 A; 3/j=2-205.
DR PDB; 6FVV; EM; 5.40 A; 3/j=2-205.
DR PDB; 6FVW; EM; 4.50 A; 3/j=2-205.
DR PDB; 6FVX; EM; 4.90 A; 3/j=2-205.
DR PDB; 6FVY; EM; 6.10 A; 3/j=2-205.
DR PDB; 6G7F; X-ray; 2.70 A; I/W=1-205.
DR PDB; 6G8M; X-ray; 2.70 A; I/W=1-205.
DR PDB; 6G8N; X-ray; 3.00 A; I/W=1-205.
DR PDB; 6GOP; X-ray; 2.90 A; I/W=1-205.
DR PDB; 6H39; X-ray; 2.50 A; I/W=1-205.
DR PDB; 6HTB; X-ray; 2.70 A; I/W=1-205.
DR PDB; 6HTC; X-ray; 2.80 A; I/W=1-205.
DR PDB; 6HTD; X-ray; 3.00 A; I/W=1-205.
DR PDB; 6HTP; X-ray; 3.00 A; I/W=1-205.
DR PDB; 6HTR; X-ray; 2.60 A; I/W=1-205.
DR PDB; 6HUB; X-ray; 2.90 A; I/W=1-205.
DR PDB; 6HUC; X-ray; 3.00 A; I/W=1-205.
DR PDB; 6HUQ; X-ray; 3.00 A; I/W=1-205.
DR PDB; 6HUU; X-ray; 2.80 A; I/W=1-205.
DR PDB; 6HUV; X-ray; 3.10 A; I/W=1-205.
DR PDB; 6HV3; X-ray; 2.70 A; I/W=1-205.
DR PDB; 6HV4; X-ray; 3.00 A; I/W=1-205.
DR PDB; 6HV5; X-ray; 3.00 A; I/W=1-205.
DR PDB; 6HV7; X-ray; 3.40 A; I/W=1-205.
DR PDB; 6HVA; X-ray; 2.90 A; I/W=1-205.
DR PDB; 6HVR; X-ray; 2.70 A; I/W=1-205.
DR PDB; 6HVS; X-ray; 3.10 A; I/W=1-205.
DR PDB; 6HVT; X-ray; 2.90 A; I/W=1-205.
DR PDB; 6HVU; X-ray; 2.90 A; I/W=1-205.
DR PDB; 6HVV; X-ray; 2.70 A; I/W=1-205.
DR PDB; 6HVW; X-ray; 3.00 A; I/W=1-205.
DR PDB; 6HVX; X-ray; 2.80 A; I/W=1-205.
DR PDB; 6HVY; X-ray; 2.70 A; I/W=1-205.
DR PDB; 6HW0; X-ray; 2.80 A; I/W=1-205.
DR PDB; 6HW3; X-ray; 2.60 A; I/W=1-205.
DR PDB; 6HW4; X-ray; 2.90 A; I/W=1-205.
DR PDB; 6HW5; X-ray; 2.90 A; I/W=1-205.
DR PDB; 6HW6; X-ray; 2.70 A; I/W=1-205.
DR PDB; 6HW7; X-ray; 2.70 A; I/W=1-205.
DR PDB; 6HW8; X-ray; 2.80 A; I/W=1-205.
DR PDB; 6HW9; X-ray; 2.80 A; I/W=1-205.
DR PDB; 6HWA; X-ray; 2.80 A; I/W=1-205.
DR PDB; 6HWB; X-ray; 2.60 A; I/W=1-205.
DR PDB; 6HWC; X-ray; 2.80 A; I/W=1-205.
DR PDB; 6HWD; X-ray; 2.80 A; I/W=1-205.
DR PDB; 6HWE; X-ray; 2.30 A; I/W=1-205.
DR PDB; 6HWF; X-ray; 2.50 A; I/W=1-205.
DR PDB; 6J2C; EM; 7.00 A; 3/h=1-205.
DR PDB; 6J2N; EM; 7.50 A; 3/h=1-205.
DR PDB; 6J2Q; EM; 3.80 A; 3/h=1-205.
DR PDB; 6J2X; EM; 3.80 A; 3/h=1-205.
DR PDB; 6J30; EM; 4.50 A; 3/h=1-205.
DR PDB; 6ZOU; X-ray; 2.90 A; I/W=1-205.
DR PDB; 6ZP6; X-ray; 2.80 A; I/W=1-205.
DR PDB; 6ZP8; X-ray; 3.00 A; I/W=1-205.
DR PDB; 7LS5; EM; 2.74 A; J/X=1-205.
DR PDB; 7LS6; EM; 3.17 A; J=1-205.
DR PDB; 7LSX; EM; 3.61 A; J=1-205.
DR PDB; 7QO3; EM; 6.10 A; 3/j=1-205.
DR PDB; 7QO5; EM; 6.00 A; 3/j=1-205.
DR PDBsum; 1FNT; -.
DR PDBsum; 1G0U; -.
DR PDBsum; 1G65; -.
DR PDBsum; 1JD2; -.
DR PDBsum; 1RYP; -.
DR PDBsum; 1Z7Q; -.
DR PDBsum; 2F16; -.
DR PDBsum; 2FAK; -.
DR PDBsum; 2GPL; -.
DR PDBsum; 2ZCY; -.
DR PDBsum; 3BDM; -.
DR PDBsum; 3D29; -.
DR PDBsum; 3DY3; -.
DR PDBsum; 3DY4; -.
DR PDBsum; 3E47; -.
DR PDBsum; 3GPJ; -.
DR PDBsum; 3GPT; -.
DR PDBsum; 3GPW; -.
DR PDBsum; 3HYE; -.
DR PDBsum; 3JCO; -.
DR PDBsum; 3JCP; -.
DR PDBsum; 3MG0; -.
DR PDBsum; 3MG4; -.
DR PDBsum; 3MG6; -.
DR PDBsum; 3MG7; -.
DR PDBsum; 3MG8; -.
DR PDBsum; 3NZJ; -.
DR PDBsum; 3NZW; -.
DR PDBsum; 3NZX; -.
DR PDBsum; 3OEU; -.
DR PDBsum; 3OEV; -.
DR PDBsum; 3OKJ; -.
DR PDBsum; 3SDI; -.
DR PDBsum; 3SDK; -.
DR PDBsum; 3SHJ; -.
DR PDBsum; 3TDD; -.
DR PDBsum; 3UN4; -.
DR PDBsum; 3UN8; -.
DR PDBsum; 3WXR; -.
DR PDBsum; 4CR2; -.
DR PDBsum; 4CR3; -.
DR PDBsum; 4CR4; -.
DR PDBsum; 4EU2; -.
DR PDBsum; 4FZC; -.
DR PDBsum; 4FZG; -.
DR PDBsum; 4G4S; -.
DR PDBsum; 4GK7; -.
DR PDBsum; 4HNP; -.
DR PDBsum; 4HRC; -.
DR PDBsum; 4HRD; -.
DR PDBsum; 4INR; -.
DR PDBsum; 4INT; -.
DR PDBsum; 4INU; -.
DR PDBsum; 4J70; -.
DR PDBsum; 4JSQ; -.
DR PDBsum; 4JSU; -.
DR PDBsum; 4JT0; -.
DR PDBsum; 4LQI; -.
DR PDBsum; 4LTC; -.
DR PDBsum; 4NNN; -.
DR PDBsum; 4NNW; -.
DR PDBsum; 4NO1; -.
DR PDBsum; 4NO6; -.
DR PDBsum; 4NO8; -.
DR PDBsum; 4NO9; -.
DR PDBsum; 4Q1S; -.
DR PDBsum; 4QBY; -.
DR PDBsum; 4QLQ; -.
DR PDBsum; 4QLS; -.
DR PDBsum; 4QLT; -.
DR PDBsum; 4QLU; -.
DR PDBsum; 4QLV; -.
DR PDBsum; 4QUX; -.
DR PDBsum; 4QUY; -.
DR PDBsum; 4QV0; -.
DR PDBsum; 4QV1; -.
DR PDBsum; 4QV3; -.
DR PDBsum; 4QV4; -.
DR PDBsum; 4QV5; -.
DR PDBsum; 4QV6; -.
DR PDBsum; 4QV7; -.
DR PDBsum; 4QV8; -.
DR PDBsum; 4QV9; -.
DR PDBsum; 4QVL; -.
DR PDBsum; 4QVM; -.
DR PDBsum; 4QVN; -.
DR PDBsum; 4QVP; -.
DR PDBsum; 4QVQ; -.
DR PDBsum; 4QVV; -.
DR PDBsum; 4QVW; -.
DR PDBsum; 4QVY; -.
DR PDBsum; 4QW0; -.
DR PDBsum; 4QW1; -.
DR PDBsum; 4QW3; -.
DR PDBsum; 4QW4; -.
DR PDBsum; 4QW5; -.
DR PDBsum; 4QW6; -.
DR PDBsum; 4QW7; -.
DR PDBsum; 4QWF; -.
DR PDBsum; 4QWG; -.
DR PDBsum; 4QWI; -.
DR PDBsum; 4QWJ; -.
DR PDBsum; 4QWK; -.
DR PDBsum; 4QWL; -.
DR PDBsum; 4QWR; -.
DR PDBsum; 4QWS; -.
DR PDBsum; 4QWU; -.
DR PDBsum; 4QWX; -.
DR PDBsum; 4QXJ; -.
DR PDBsum; 4QZ0; -.
DR PDBsum; 4QZ1; -.
DR PDBsum; 4QZ2; -.
DR PDBsum; 4QZ3; -.
DR PDBsum; 4QZ4; -.
DR PDBsum; 4QZ5; -.
DR PDBsum; 4QZ6; -.
DR PDBsum; 4QZ7; -.
DR PDBsum; 4QZW; -.
DR PDBsum; 4QZX; -.
DR PDBsum; 4QZZ; -.
DR PDBsum; 4R00; -.
DR PDBsum; 4R02; -.
DR PDBsum; 4R17; -.
DR PDBsum; 4R18; -.
DR PDBsum; 4RUR; -.
DR PDBsum; 4V7O; -.
DR PDBsum; 4X6Z; -.
DR PDBsum; 4Y69; -.
DR PDBsum; 4Y6A; -.
DR PDBsum; 4Y6V; -.
DR PDBsum; 4Y6Z; -.
DR PDBsum; 4Y70; -.
DR PDBsum; 4Y74; -.
DR PDBsum; 4Y75; -.
DR PDBsum; 4Y77; -.
DR PDBsum; 4Y78; -.
DR PDBsum; 4Y7W; -.
DR PDBsum; 4Y7X; -.
DR PDBsum; 4Y7Y; -.
DR PDBsum; 4Y80; -.
DR PDBsum; 4Y81; -.
DR PDBsum; 4Y82; -.
DR PDBsum; 4Y84; -.
DR PDBsum; 4Y8G; -.
DR PDBsum; 4Y8H; -.
DR PDBsum; 4Y8I; -.
DR PDBsum; 4Y8J; -.
DR PDBsum; 4Y8K; -.
DR PDBsum; 4Y8L; -.
DR PDBsum; 4Y8M; -.
DR PDBsum; 4Y8N; -.
DR PDBsum; 4Y8O; -.
DR PDBsum; 4Y8P; -.
DR PDBsum; 4Y8Q; -.
DR PDBsum; 4Y8R; -.
DR PDBsum; 4Y8S; -.
DR PDBsum; 4Y8T; -.
DR PDBsum; 4Y8U; -.
DR PDBsum; 4Y9Y; -.
DR PDBsum; 4Y9Z; -.
DR PDBsum; 4YA0; -.
DR PDBsum; 4YA1; -.
DR PDBsum; 4YA2; -.
DR PDBsum; 4YA3; -.
DR PDBsum; 4YA4; -.
DR PDBsum; 4YA5; -.
DR PDBsum; 4YA7; -.
DR PDBsum; 4YA9; -.
DR PDBsum; 4Z1L; -.
DR PDBsum; 5A5B; -.
DR PDBsum; 5AHJ; -.
DR PDBsum; 5BOU; -.
DR PDBsum; 5BXL; -.
DR PDBsum; 5BXN; -.
DR PDBsum; 5CGF; -.
DR PDBsum; 5CGG; -.
DR PDBsum; 5CGH; -.
DR PDBsum; 5CGI; -.
DR PDBsum; 5CZ4; -.
DR PDBsum; 5CZ5; -.
DR PDBsum; 5CZ6; -.
DR PDBsum; 5CZ7; -.
DR PDBsum; 5CZ8; -.
DR PDBsum; 5CZ9; -.
DR PDBsum; 5CZA; -.
DR PDBsum; 5D0S; -.
DR PDBsum; 5D0T; -.
DR PDBsum; 5D0V; -.
DR PDBsum; 5D0W; -.
DR PDBsum; 5D0X; -.
DR PDBsum; 5D0Z; -.
DR PDBsum; 5DKI; -.
DR PDBsum; 5DKJ; -.
DR PDBsum; 5FG7; -.
DR PDBsum; 5FG9; -.
DR PDBsum; 5FGA; -.
DR PDBsum; 5FGD; -.
DR PDBsum; 5FGE; -.
DR PDBsum; 5FGF; -.
DR PDBsum; 5FGG; -.
DR PDBsum; 5FGH; -.
DR PDBsum; 5FGI; -.
DR PDBsum; 5FHS; -.
DR PDBsum; 5JHR; -.
DR PDBsum; 5JHS; -.
DR PDBsum; 5L52; -.
DR PDBsum; 5L54; -.
DR PDBsum; 5L55; -.
DR PDBsum; 5L5A; -.
DR PDBsum; 5L5B; -.
DR PDBsum; 5L5D; -.
DR PDBsum; 5L5E; -.
DR PDBsum; 5L5F; -.
DR PDBsum; 5L5H; -.
DR PDBsum; 5L5I; -.
DR PDBsum; 5L5J; -.
DR PDBsum; 5L5O; -.
DR PDBsum; 5L5P; -.
DR PDBsum; 5L5Q; -.
DR PDBsum; 5L5R; -.
DR PDBsum; 5L5S; -.
DR PDBsum; 5L5T; -.
DR PDBsum; 5L5U; -.
DR PDBsum; 5L5V; -.
DR PDBsum; 5L5W; -.
DR PDBsum; 5L5X; -.
DR PDBsum; 5L5Y; -.
DR PDBsum; 5L5Z; -.
DR PDBsum; 5L60; -.
DR PDBsum; 5L61; -.
DR PDBsum; 5L62; -.
DR PDBsum; 5L63; -.
DR PDBsum; 5L64; -.
DR PDBsum; 5L65; -.
DR PDBsum; 5L66; -.
DR PDBsum; 5L67; -.
DR PDBsum; 5L68; -.
DR PDBsum; 5L69; -.
DR PDBsum; 5L6A; -.
DR PDBsum; 5L6B; -.
DR PDBsum; 5L6C; -.
DR PDBsum; 5LAI; -.
DR PDBsum; 5LAJ; -.
DR PDBsum; 5LTT; -.
DR PDBsum; 5M2B; -.
DR PDBsum; 5MP9; -.
DR PDBsum; 5MPA; -.
DR PDBsum; 5MPB; -.
DR PDBsum; 5MPC; -.
DR PDBsum; 5NIF; -.
DR PDBsum; 5WVI; -.
DR PDBsum; 5WVK; -.
DR PDBsum; 6EF3; -.
DR PDBsum; 6FVT; -.
DR PDBsum; 6FVU; -.
DR PDBsum; 6FVV; -.
DR PDBsum; 6FVW; -.
DR PDBsum; 6FVX; -.
DR PDBsum; 6FVY; -.
DR PDBsum; 6G7F; -.
DR PDBsum; 6G8M; -.
DR PDBsum; 6G8N; -.
DR PDBsum; 6GOP; -.
DR PDBsum; 6H39; -.
DR PDBsum; 6HTB; -.
DR PDBsum; 6HTC; -.
DR PDBsum; 6HTD; -.
DR PDBsum; 6HTP; -.
DR PDBsum; 6HTR; -.
DR PDBsum; 6HUB; -.
DR PDBsum; 6HUC; -.
DR PDBsum; 6HUQ; -.
DR PDBsum; 6HUU; -.
DR PDBsum; 6HUV; -.
DR PDBsum; 6HV3; -.
DR PDBsum; 6HV4; -.
DR PDBsum; 6HV5; -.
DR PDBsum; 6HV7; -.
DR PDBsum; 6HVA; -.
DR PDBsum; 6HVR; -.
DR PDBsum; 6HVS; -.
DR PDBsum; 6HVT; -.
DR PDBsum; 6HVU; -.
DR PDBsum; 6HVV; -.
DR PDBsum; 6HVW; -.
DR PDBsum; 6HVX; -.
DR PDBsum; 6HVY; -.
DR PDBsum; 6HW0; -.
DR PDBsum; 6HW3; -.
DR PDBsum; 6HW4; -.
DR PDBsum; 6HW5; -.
DR PDBsum; 6HW6; -.
DR PDBsum; 6HW7; -.
DR PDBsum; 6HW8; -.
DR PDBsum; 6HW9; -.
DR PDBsum; 6HWA; -.
DR PDBsum; 6HWB; -.
DR PDBsum; 6HWC; -.
DR PDBsum; 6HWD; -.
DR PDBsum; 6HWE; -.
DR PDBsum; 6HWF; -.
DR PDBsum; 6J2C; -.
DR PDBsum; 6J2N; -.
DR PDBsum; 6J2Q; -.
DR PDBsum; 6J2X; -.
DR PDBsum; 6J30; -.
DR PDBsum; 6ZOU; -.
DR PDBsum; 6ZP6; -.
DR PDBsum; 6ZP8; -.
DR PDBsum; 7LS5; -.
DR PDBsum; 7LS6; -.
DR PDBsum; 7LSX; -.
DR PDBsum; 7QO3; -.
DR PDBsum; 7QO5; -.
DR AlphaFoldDB; P25451; -.
DR SMR; P25451; -.
DR BioGRID; 36840; 430.
DR ComplexPortal; CPX-2262; 26S Proteasome complex.
DR DIP; DIP-2039N; -.
DR IntAct; P25451; 13.
DR MINT; P25451; -.
DR STRING; 4932.YER094C; -.
DR iPTMnet; P25451; -.
DR MaxQB; P25451; -.
DR PaxDb; P25451; -.
DR PRIDE; P25451; -.
DR EnsemblFungi; YER094C_mRNA; YER094C; YER094C.
DR GeneID; 856830; -.
DR KEGG; sce:YER094C; -.
DR SGD; S000000896; PUP3.
DR VEuPathDB; FungiDB:YER094C; -.
DR eggNOG; KOG0180; Eukaryota.
DR GeneTree; ENSGT00550000074820; -.
DR HOGENOM; CLU_035750_10_0_1; -.
DR InParanoid; P25451; -.
DR OMA; GWGAIVH; -.
DR BioCyc; YEAST:G3O-30261-MON; -.
DR Reactome; R-SCE-1236978; Cross-presentation of soluble exogenous antigens (endosomes).
DR Reactome; R-SCE-382556; ABC-family proteins mediated transport.
DR Reactome; R-SCE-5668541; TNFR2 non-canonical NF-kB pathway.
DR Reactome; R-SCE-5687128; MAPK6/MAPK4 signaling.
DR Reactome; R-SCE-5689880; Ub-specific processing proteases.
DR Reactome; R-SCE-68949; Orc1 removal from chromatin.
DR Reactome; R-SCE-69017; CDK-mediated phosphorylation and removal of Cdc6.
DR Reactome; R-SCE-69601; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
DR Reactome; R-SCE-75815; Ubiquitin-dependent degradation of Cyclin D.
DR Reactome; R-SCE-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis.
DR Reactome; R-SCE-8948751; Regulation of PTEN stability and activity.
DR Reactome; R-SCE-8951664; Neddylation.
DR Reactome; R-SCE-9755511; KEAP1-NFE2L2 pathway.
DR Reactome; R-SCE-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR EvolutionaryTrace; P25451; -.
DR PRO; PR:P25451; -.
DR Proteomes; UP000002311; Chromosome V.
DR RNAct; P25451; protein.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IC:SGD.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
DR GO; GO:0000502; C:proteasome complex; IPI:ComplexPortal.
DR GO; GO:0005839; C:proteasome core complex; IBA:GO_Central.
DR GO; GO:0019774; C:proteasome core complex, beta-subunit complex; IDA:SGD.
DR GO; GO:0034515; C:proteasome storage granule; IC:SGD.
DR GO; GO:0061133; F:endopeptidase activator activity; IGI:SGD.
DR GO; GO:0010498; P:proteasomal protein catabolic process; IBA:GO_Central.
DR GO; GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:SGD.
DR CDD; cd03759; proteasome_beta_type_3; 1.
DR Gene3D; 3.60.20.10; -; 1.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR InterPro; IPR033811; Proteasome_beta_3.
DR InterPro; IPR016050; Proteasome_bsu_CS.
DR InterPro; IPR001353; Proteasome_sua/b.
DR InterPro; IPR023333; Proteasome_suB-type.
DR PANTHER; PTHR11599:SF62; PTHR11599:SF62; 1.
DR Pfam; PF00227; Proteasome; 1.
DR SUPFAM; SSF56235; SSF56235; 1.
DR PROSITE; PS00854; PROTEASOME_BETA_1; 1.
DR PROSITE; PS51476; PROTEASOME_BETA_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Isopeptide bond; Nucleus; Phosphoprotein;
KW Proteasome; Reference proteome; Ubl conjugation.
FT CHAIN 1..205
FT /note="Proteasome subunit beta type-3"
FT /id="PRO_0000148070"
FT MOD_RES 31
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18407956"
FT CROSSLNK 70
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in ubiquitin)"
FT /evidence="ECO:0007744|PubMed:22106047"
FT HELIX 4..6
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 11..16
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 18..26
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 29..31
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 34..38
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 43..46
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 49..55
FT /evidence="ECO:0007829|PDB:1RYP"
FT HELIX 57..78
FT /evidence="ECO:0007829|PDB:1RYP"
FT HELIX 84..96
FT /evidence="ECO:0007829|PDB:1RYP"
FT TURN 97..100
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 105..112
FT /evidence="ECO:0007829|PDB:1RYP"
FT TURN 114..116
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 119..124
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 130..132
FT /evidence="ECO:0007829|PDB:1G65"
FT STRAND 134..140
FT /evidence="ECO:0007829|PDB:1RYP"
FT HELIX 143..153
FT /evidence="ECO:0007829|PDB:1RYP"
FT HELIX 160..175
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 178..181
FT /evidence="ECO:0007829|PDB:4NNN"
FT STRAND 185..193
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 195..200
FT /evidence="ECO:0007829|PDB:1RYP"
SQ SEQUENCE 205 AA; 22605 MW; 5AA92D746454BCB7 CRC64;
MSDPSSINGG IVVAMTGKDC VAIACDLRLG SQSLGVSNKF EKIFHYGHVF LGITGLATDV
TTLNEMFRYK TNLYKLKEER AIEPETFTQL VSSSLYERRF GPYFVGPVVA GINSKSGKPF
IAGFDLIGCI DEAKDFIVSG TASDQLFGMC ESLYEPNLEP EDLFETISQA LLNAADRDAL
SGWGAVVYII KKDEVVKRYL KMRQD
