PSB7_YEAST
ID PSB7_YEAST Reviewed; 266 AA.
AC P30657; D6VTT3; E9P8Z8;
DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1993, sequence version 1.
DT 03-AUG-2022, entry version 217.
DE RecName: Full=Proteasome subunit beta type-7;
DE AltName: Full=Macropain subunit PRE4;
DE AltName: Full=Multicatalytic endopeptidase complex subunit PRE4;
DE AltName: Full=Proteasome component PRE4;
DE AltName: Full=Proteinase YSCE subunit PRE4;
DE Flags: Precursor;
GN Name=PRE4; OrderedLocusNames=YFR050C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, CATALYTIC ACTIVITY, AND
RP SUBUNIT.
RX PubMed=8381431; DOI=10.1016/s0021-9258(18)53719-4;
RA Hilt W., Enenkel C., Gruhler A., Singer T., Wolf D.H.;
RT "The PRE4 gene codes for a subunit of the yeast proteasome necessary for
RT peptidylglutamyl-peptide-hydrolyzing activity. Mutations link the
RT proteasome to stress- and ubiquitin-dependent proteolysis.";
RL J. Biol. Chem. 268:3479-3486(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204511 / S288c / AB972;
RX PubMed=8686379;
RX DOI=10.1002/(sici)1097-0061(199602)12:2<149::aid-yea893>3.0.co;2-g;
RA Eki T., Naitou M., Hagiwara H., Ozawa M., Sasanuma S., Sasanuma M.,
RA Tsuchiya Y., Shibata T., Hanaoka F., Murakami Y.;
RT "Analysis of a 36.2 kb DNA sequence including the right telomere of
RT chromosome VI from Saccharomyces cerevisiae.";
RL Yeast 12:149-167(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7670463; DOI=10.1038/ng0795-261;
RA Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S.,
RA Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H.,
RA Eki T.;
RT "Analysis of the nucleotide sequence of chromosome VI from Saccharomyces
RT cerevisiae.";
RL Nat. Genet. 10:261-268(1995).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [6]
RP INTERACTION WITH CIC1.
RX PubMed=11500370; DOI=10.1093/emboj/20.16.4423;
RA Jaeger S., Strayle J., Heinemeyer W., Wolf D.H.;
RT "Cic1, an adaptor protein specifically linking the 26S proteasome to its
RT substrate, the SCF component Cdc4.";
RL EMBO J. 20:4423-4431(2001).
RN [7]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [8]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [9]
RP X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 34-266 OF COMPLEX WITH THE 20S
RP PROTEASOME, AND PROTEOLYTIC PROCESSING.
RX PubMed=9087403; DOI=10.1038/386463a0;
RA Groll M., Ditzel L., Loewe J., Stock D., Bochtler M., Bartunik H.D.,
RA Huber R.;
RT "Structure of 20S proteasome from yeast at 2.4-A resolution.";
RL Nature 386:463-471(1997).
RN [10]
RP X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF 34-266 OF COMPLEX WITH THE 20S
RP PROTEASOME AND A 11S REGULATORY COMPLEX.
RX PubMed=11081519; DOI=10.1038/35040607;
RA Whitby F.G., Masters E.I., Kramer L., Knowlton J.R., Yao Y., Wang C.C.,
RA Hill C.P.;
RT "Structural basis for the activation of 20S proteasomes by 11S
RT regulators.";
RL Nature 408:115-120(2000).
RN [11]
RP X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF COMPLEX WITH THE 20S PROTEASOME.
RX PubMed=11062564; DOI=10.1038/80992;
RA Groll M., Bajorek M., Koehler A., Moroder L., Rubin D.M., Huber R.,
RA Glickman M.H., Finley D.;
RT "A gated channel into the proteasome core particle.";
RL Nat. Struct. Biol. 7:1062-1067(2000).
RN [12]
RP X-RAY CRYSTALLOGRAPHY (2.81 ANGSTROMS) OF 34-266 OF COMPLEX WITH THE 20S
RP PROTEASOME AND A TMC-95-BASED INHIBITOR.
RX PubMed=16793518; DOI=10.1016/j.chembiol.2006.04.005;
RA Groll M., Goetz M., Kaiser M., Weyher E., Moroder L.;
RT "TMC-95-based inhibitor design provides evidence for the catalytic
RT versatility of the proteasome.";
RL Chem. Biol. 13:607-614(2006).
RN [13]
RP X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 34-266 OF COMPLEX WITH THE 20S
RP PROTEASOME AND SALINOSPORAMIDE.
RX PubMed=16608349; DOI=10.1021/ja058320b;
RA Groll M., Huber R., Potts B.C.M.;
RT "Crystal structures of salinosporamide A (NPI-0052) and B (NPI-0047) in
RT complex with the 20S proteasome reveal important consequences of beta-
RT lactone ring opening and a mechanism for irreversible binding.";
RL J. Am. Chem. Soc. 128:5136-5141(2006).
RN [14]
RP X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 34-266 OF COMPLEX WITH THE 20S
RP PROTEASOME AND BORTEZOMIB.
RX PubMed=16531229; DOI=10.1016/j.str.2005.11.019;
RA Groll M., Berkers C.R., Ploegh H.L., Ovaa H.;
RT "Crystal structure of the boronic acid-based proteasome inhibitor
RT bortezomib in complex with the yeast 20S proteasome.";
RL Structure 14:451-456(2006).
RN [15]
RP X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 34-266 IN COMPLEX WITH THE
RP PROTEASOME.
RX PubMed=20227375; DOI=10.1016/j.molcel.2010.02.002;
RA Sadre-Bazzaz K., Whitby F.G., Robinson H., Formosa T., Hill C.P.;
RT "Structure of a Blm10 complex reveals common mechanisms for proteasome
RT binding and gate opening.";
RL Mol. Cell 37:728-735(2010).
RN [16]
RP STRUCTURE BY ELECTRON MICROSCOPY (7.4 ANGSTROMS) OF THE 26S PROTEASOME.
RX PubMed=22927375; DOI=10.1073/pnas.1213333109;
RA Beck F., Unverdorben P., Bohn S., Schweitzer A., Pfeifer G., Sakata E.,
RA Nickell S., Plitzko J.M., Villa E., Baumeister W., Forster F.;
RT "Near-atomic resolution structural model of the yeast 26S proteasome.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:14870-14875(2012).
CC -!- FUNCTION: Non-catalytic component of the proteasome which degrades
CC poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is
CC essential for the regulated turnover of proteins and for the removal of
CC misfolded proteins. The proteasome is a multicatalytic proteinase
CC complex that is characterized by its ability to cleave peptides with
CC Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or
CC slightly basic pH. It has an ATP-dependent proteolytic activity. PRE3
CC and PRE4 are necessary for the peptidyl-glutamyl-peptide-hydrolyzing
CC activity. {ECO:0000269|PubMed:8381431}.
CC -!- SUBUNIT: The 26S proteasome consists of a 20S proteasome core and two
CC 19S regulatory subunits. The 20S proteasome core is composed of 28
CC subunits that are arranged in four stacked rings, resulting in a
CC barrel-shaped structure. The two end rings are each formed by seven
CC alpha subunits, and the two central rings are each formed by seven beta
CC subunits. The catalytic chamber with the active sites is on the inside
CC of the barrel. Interacts with CIC1. {ECO:0000269|PubMed:11500370,
CC ECO:0000269|PubMed:20227375, ECO:0000269|PubMed:8381431}.
CC -!- INTERACTION:
CC P30657; P30656: PRE2; NbExp=2; IntAct=EBI-13997, EBI-14001;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|PROSITE-ProRule:PRU00809,
CC ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 16900 molecules/cell in log phase SD
CC medium. {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the peptidase T1B family. {ECO:0000255|PROSITE-
CC ProRule:PRU00809}.
CC -!- CAUTION: It is uncertain whether Met-1 or Met-31 is the initiator.
CC {ECO:0000305}.
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DR EMBL; X68663; CAA48629.1; -; Genomic_DNA.
DR EMBL; D50617; BAA09289.1; -; Genomic_DNA.
DR EMBL; AY692947; AAT92966.1; -; Genomic_DNA.
DR EMBL; BK006940; DAA12493.1; -; Genomic_DNA.
DR PIR; A46610; A46610.
DR RefSeq; NP_116708.1; NM_001180015.1.
DR PDB; 1FNT; X-ray; 3.20 A; N/b=34-265.
DR PDB; 1G0U; X-ray; 2.40 A; 1/M=1-266.
DR PDB; 1G65; X-ray; 2.25 A; 1/M=34-266.
DR PDB; 1JD2; X-ray; 3.00 A; M/T=34-266.
DR PDB; 1RYP; X-ray; 1.90 A; 2/N=34-266.
DR PDB; 1Z7Q; X-ray; 3.22 A; N/b=34-266.
DR PDB; 2F16; X-ray; 2.80 A; 1/M=34-266.
DR PDB; 2FAK; X-ray; 2.80 A; 1/M=34-266.
DR PDB; 2GPL; X-ray; 2.81 A; 1/M=34-266.
DR PDB; 2ZCY; X-ray; 2.90 A; 0/M=1-266.
DR PDB; 3BDM; X-ray; 2.70 A; 0/M=1-266.
DR PDB; 3D29; X-ray; 2.60 A; 1/M=34-266.
DR PDB; 3DY3; X-ray; 2.81 A; 1/M=34-266.
DR PDB; 3DY4; X-ray; 2.80 A; 1/M=34-266.
DR PDB; 3E47; X-ray; 3.00 A; 1/M=34-266.
DR PDB; 3GPJ; X-ray; 2.70 A; 1/M=34-266.
DR PDB; 3GPT; X-ray; 2.41 A; 1/M=34-266.
DR PDB; 3GPW; X-ray; 2.50 A; 1/M=34-266.
DR PDB; 3HYE; X-ray; 2.50 A; 1/M=34-266.
DR PDB; 3JCO; EM; 4.80 A; 2/9=1-266.
DR PDB; 3JCP; EM; 4.60 A; 2/9=1-266.
DR PDB; 3MG0; X-ray; 2.68 A; 1/M=34-266.
DR PDB; 3MG4; X-ray; 3.11 A; 1/M=34-266.
DR PDB; 3MG6; X-ray; 2.60 A; 1/M=1-266.
DR PDB; 3MG7; X-ray; 2.78 A; 1/M=1-266.
DR PDB; 3MG8; X-ray; 2.59 A; 1/M=1-266.
DR PDB; 3NZJ; X-ray; 2.40 A; 1/M=1-266.
DR PDB; 3NZW; X-ray; 2.50 A; 1/M=1-266.
DR PDB; 3NZX; X-ray; 2.70 A; 1/M=1-266.
DR PDB; 3OEU; X-ray; 2.60 A; 1/M=34-266.
DR PDB; 3OEV; X-ray; 2.85 A; 1/M=34-266.
DR PDB; 3OKJ; X-ray; 2.70 A; 1/M=34-266.
DR PDB; 3SDI; X-ray; 2.65 A; 1/M=34-253.
DR PDB; 3SDK; X-ray; 2.70 A; 1/M=34-266.
DR PDB; 3SHJ; X-ray; 2.80 A; 1/M=34-266.
DR PDB; 3TDD; X-ray; 2.70 A; 1/M=34-266.
DR PDB; 3UN4; X-ray; 3.40 A; M/a=34-266.
DR PDB; 3UN8; X-ray; 2.70 A; M/a=34-266.
DR PDB; 3WXR; X-ray; 3.15 A; 2/N=1-266.
DR PDB; 4CR2; EM; 7.70 A; 7=1-266.
DR PDB; 4CR3; EM; 9.30 A; 7=1-266.
DR PDB; 4CR4; EM; 8.80 A; 7=1-266.
DR PDB; 4EU2; X-ray; 2.51 A; 2/N=34-266.
DR PDB; 4FZC; X-ray; 2.80 A; M/a=34-266.
DR PDB; 4FZG; X-ray; 3.00 A; M/a=34-266.
DR PDB; 4G4S; X-ray; 2.49 A; N=34-266.
DR PDB; 4GK7; X-ray; 2.80 A; M/a=34-266.
DR PDB; 4HNP; X-ray; 2.80 A; M/a=34-266.
DR PDB; 4HRC; X-ray; 2.80 A; M/a=34-266.
DR PDB; 4HRD; X-ray; 2.80 A; M/a=34-266.
DR PDB; 4INR; X-ray; 2.70 A; M/a=34-266.
DR PDB; 4INT; X-ray; 2.90 A; M/a=34-266.
DR PDB; 4INU; X-ray; 3.10 A; M/a=34-266.
DR PDB; 4J70; X-ray; 2.80 A; M/a=34-266.
DR PDB; 4JSQ; X-ray; 2.80 A; M/a=34-266.
DR PDB; 4JSU; X-ray; 2.90 A; M/a=34-266.
DR PDB; 4JT0; X-ray; 3.10 A; M/a=34-266.
DR PDB; 4LQI; X-ray; 2.70 A; M/a=34-266.
DR PDB; 4LTC; X-ray; 2.50 A; M/a=34-266.
DR PDB; 4NNN; X-ray; 2.50 A; M/a=21-266.
DR PDB; 4NNW; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4NO1; X-ray; 2.50 A; M/a=21-266.
DR PDB; 4NO6; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4NO8; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4NO9; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4Q1S; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4QBY; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QLQ; X-ray; 2.40 A; M/a=21-266.
DR PDB; 4QLS; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QLT; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QLU; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QLV; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4QUX; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QUY; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QV0; X-ray; 3.10 A; M/a=21-266.
DR PDB; 4QV1; X-ray; 2.50 A; M/a=21-266.
DR PDB; 4QV3; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QV4; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4QV5; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4QV6; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QV7; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4QV8; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4QV9; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4QVL; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QVM; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QVN; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4QVP; X-ray; 2.30 A; M/a=21-266.
DR PDB; 4QVQ; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4QVV; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QVW; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QVY; X-ray; 2.51 A; M/a=21-266.
DR PDB; 4QW0; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4QW1; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4QW3; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4QW4; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QW5; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QW6; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4QW7; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4QWF; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QWG; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4QWI; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4QWJ; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4QWK; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QWL; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4QWR; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4QWS; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QWU; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QWX; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4QXJ; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QZ0; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QZ1; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QZ2; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4QZ3; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QZ4; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QZ5; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QZ6; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4QZ7; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4QZW; X-ray; 3.00 A; M/a=21-266.
DR PDB; 4QZX; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4QZZ; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4R00; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4R02; X-ray; 2.50 A; M/a=21-266.
DR PDB; 4R17; X-ray; 2.10 A; M/a=21-266.
DR PDB; 4R18; X-ray; 2.40 A; M/a=21-266.
DR PDB; 4RUR; X-ray; 2.50 A; M/a=21-266.
DR PDB; 4V7O; X-ray; 3.00 A; A4/AR/B2/BN=34-266.
DR PDB; 4X6Z; X-ray; 2.70 A; 2/N=1-266.
DR PDB; 4Y69; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4Y6A; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4Y6V; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4Y6Z; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4Y70; X-ray; 2.40 A; M/a=21-266.
DR PDB; 4Y74; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4Y75; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4Y77; X-ray; 2.50 A; M/a=21-266.
DR PDB; 4Y78; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4Y7W; X-ray; 2.50 A; M/a=21-266.
DR PDB; 4Y7X; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4Y7Y; X-ray; 2.40 A; M/a=21-266.
DR PDB; 4Y80; X-ray; 2.50 A; M/a=21-266.
DR PDB; 4Y81; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4Y82; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4Y84; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4Y8G; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4Y8H; X-ray; 2.50 A; M/a=21-266.
DR PDB; 4Y8I; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4Y8J; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4Y8K; X-ray; 2.60 A; M/a=21-266.
DR PDB; 4Y8L; X-ray; 2.40 A; M/a=21-266.
DR PDB; 4Y8M; X-ray; 2.80 A; M/a=21-259.
DR PDB; 4Y8N; X-ray; 2.60 A; M/a=21-259.
DR PDB; 4Y8O; X-ray; 2.70 A; M/a=21-259.
DR PDB; 4Y8P; X-ray; 2.80 A; M/a=21-259.
DR PDB; 4Y8Q; X-ray; 2.60 A; M/a=21-259.
DR PDB; 4Y8R; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4Y8S; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4Y8T; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4Y8U; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4Y9Y; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4Y9Z; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4YA0; X-ray; 2.80 A; M/a=21-266.
DR PDB; 4YA1; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4YA2; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4YA3; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4YA4; X-ray; 2.90 A; M/a=21-266.
DR PDB; 4YA5; X-ray; 2.50 A; M/a=21-266.
DR PDB; 4YA7; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4YA9; X-ray; 2.70 A; M/a=21-266.
DR PDB; 4Z1L; X-ray; 3.00 A; M/a=21-266.
DR PDB; 5A5B; EM; 9.50 A; 7=1-266.
DR PDB; 5AHJ; X-ray; 2.80 A; M/a=34-266.
DR PDB; 5BOU; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5BXL; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5BXN; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5CGF; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5CGG; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5CGH; X-ray; 2.50 A; M/a=21-266.
DR PDB; 5CGI; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5CZ4; X-ray; 2.30 A; M/a=21-266.
DR PDB; 5CZ5; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5CZ6; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5CZ7; X-ray; 2.50 A; M/a=21-266.
DR PDB; 5CZ8; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5CZ9; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5CZA; X-ray; 2.50 A; M/a=21-266.
DR PDB; 5D0S; X-ray; 2.50 A; M/a=21-266.
DR PDB; 5D0T; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5D0V; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5D0W; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5D0X; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5D0Z; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5DKI; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5DKJ; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5FG7; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5FG9; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5FGA; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5FGD; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5FGE; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5FGF; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5FGG; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5FGH; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5FGI; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5FHS; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5JHR; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5JHS; X-ray; 3.00 A; M/a=21-266.
DR PDB; 5L52; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5L54; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5L55; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5L5A; X-ray; 2.40 A; M/a=21-266.
DR PDB; 5L5B; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5L5D; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5L5E; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5L5F; X-ray; 2.50 A; M/a=21-266.
DR PDB; 5L5H; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5L5I; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5L5J; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5L5O; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5L5P; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5L5Q; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5L5R; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5L5S; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5L5T; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5L5U; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5L5V; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5L5W; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5L5X; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5L5Y; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5L5Z; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5L60; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5L61; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5L62; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5L63; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5L64; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5L65; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5L66; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5L67; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5L68; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5L69; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5L6A; X-ray; 2.80 A; M/a=21-266.
DR PDB; 5L6B; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5L6C; X-ray; 2.60 A; M/a=21-266.
DR PDB; 5LAI; X-ray; 2.50 A; M/a=21-266.
DR PDB; 5LAJ; X-ray; 2.90 A; M/a=21-266.
DR PDB; 5LTT; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5M2B; X-ray; 2.70 A; M/a=21-266.
DR PDB; 5MP9; EM; 4.10 A; 7/n=1-266.
DR PDB; 5MPA; EM; 4.50 A; 7/n=1-266.
DR PDB; 5MPB; EM; 7.80 A; 7/n=1-266.
DR PDB; 5MPC; EM; 7.70 A; 7/n=1-266.
DR PDB; 5NIF; X-ray; 3.00 A; 2/N=1-266.
DR PDB; 5WVI; EM; 6.30 A; 7/a=1-266.
DR PDB; 5WVK; EM; 4.20 A; 7/a=1-266.
DR PDB; 6EF3; EM; 4.17 A; 7=1-266.
DR PDB; 6FVT; EM; 4.10 A; 7/n=34-265.
DR PDB; 6FVU; EM; 4.50 A; 7/n=34-265.
DR PDB; 6FVV; EM; 5.40 A; 7/n=34-265.
DR PDB; 6FVW; EM; 4.50 A; 7/n=34-265.
DR PDB; 6FVX; EM; 4.90 A; 7/n=34-265.
DR PDB; 6FVY; EM; 6.10 A; 7/n=34-265.
DR PDB; 6G7F; X-ray; 2.70 A; M/a=21-266.
DR PDB; 6G8M; X-ray; 2.70 A; M/a=21-266.
DR PDB; 6G8N; X-ray; 3.00 A; M/a=21-266.
DR PDB; 6GOP; X-ray; 2.90 A; M/a=21-266.
DR PDB; 6H39; X-ray; 2.50 A; M/a=21-266.
DR PDB; 6HTB; X-ray; 2.70 A; M/a=21-266.
DR PDB; 6HTC; X-ray; 2.80 A; M/a=21-266.
DR PDB; 6HTD; X-ray; 3.00 A; M/a=21-266.
DR PDB; 6HTP; X-ray; 3.00 A; M/a=21-266.
DR PDB; 6HTR; X-ray; 2.60 A; M/a=21-266.
DR PDB; 6HUB; X-ray; 2.90 A; M/a=21-266.
DR PDB; 6HUC; X-ray; 3.00 A; M/a=21-266.
DR PDB; 6HUQ; X-ray; 3.00 A; M/a=21-266.
DR PDB; 6HUU; X-ray; 2.80 A; M/a=21-266.
DR PDB; 6HUV; X-ray; 3.10 A; M/a=21-266.
DR PDB; 6HV3; X-ray; 2.70 A; M/a=21-266.
DR PDB; 6HV4; X-ray; 3.00 A; M/a=21-266.
DR PDB; 6HV5; X-ray; 3.00 A; M/a=21-266.
DR PDB; 6HV7; X-ray; 3.40 A; M/a=21-266.
DR PDB; 6HVA; X-ray; 2.90 A; M/a=21-266.
DR PDB; 6HVR; X-ray; 2.70 A; M/a=21-266.
DR PDB; 6HVS; X-ray; 3.10 A; M/a=21-266.
DR PDB; 6HVT; X-ray; 2.90 A; M/a=21-266.
DR PDB; 6HVU; X-ray; 2.90 A; M/a=21-266.
DR PDB; 6HVV; X-ray; 2.70 A; M/a=21-266.
DR PDB; 6HVW; X-ray; 3.00 A; M/a=21-266.
DR PDB; 6HVX; X-ray; 2.80 A; M/a=21-266.
DR PDB; 6HVY; X-ray; 2.70 A; M/a=21-266.
DR PDB; 6HW0; X-ray; 2.80 A; M/a=21-266.
DR PDB; 6HW3; X-ray; 2.60 A; M/a=21-266.
DR PDB; 6HW4; X-ray; 2.90 A; M/a=21-266.
DR PDB; 6HW5; X-ray; 2.90 A; M/a=21-266.
DR PDB; 6HW6; X-ray; 2.70 A; M/a=21-266.
DR PDB; 6HW7; X-ray; 2.70 A; M/a=21-266.
DR PDB; 6HW8; X-ray; 2.80 A; M/a=21-266.
DR PDB; 6HW9; X-ray; 2.80 A; M/a=21-266.
DR PDB; 6HWA; X-ray; 2.80 A; M/a=21-266.
DR PDB; 6HWB; X-ray; 2.60 A; M/a=21-266.
DR PDB; 6HWC; X-ray; 2.80 A; M/a=21-266.
DR PDB; 6HWD; X-ray; 2.80 A; M/a=21-266.
DR PDB; 6HWE; X-ray; 2.30 A; M/a=21-266.
DR PDB; 6HWF; X-ray; 2.50 A; M/a=21-266.
DR PDB; 6J2C; EM; 7.00 A; 7/a=1-266.
DR PDB; 6J2N; EM; 7.50 A; 7/a=1-266.
DR PDB; 6J2Q; EM; 3.80 A; 7/a=1-266.
DR PDB; 6J2X; EM; 3.80 A; 7/a=1-266.
DR PDB; 6J30; EM; 4.50 A; 7/a=1-266.
DR PDB; 6ZOU; X-ray; 2.90 A; M/a=21-266.
DR PDB; 6ZP6; X-ray; 2.80 A; M/a=21-266.
DR PDB; 6ZP8; X-ray; 3.00 A; M/a=21-266.
DR PDB; 7LS5; EM; 2.74 A; 2/N=1-266.
DR PDB; 7O2L; X-ray; 3.00 A; M/a=21-266.
DR PDB; 7QO3; EM; 6.10 A; 7/n=1-266.
DR PDB; 7QO5; EM; 6.00 A; 7/n=1-266.
DR PDBsum; 1FNT; -.
DR PDBsum; 1G0U; -.
DR PDBsum; 1G65; -.
DR PDBsum; 1JD2; -.
DR PDBsum; 1RYP; -.
DR PDBsum; 1Z7Q; -.
DR PDBsum; 2F16; -.
DR PDBsum; 2FAK; -.
DR PDBsum; 2GPL; -.
DR PDBsum; 2ZCY; -.
DR PDBsum; 3BDM; -.
DR PDBsum; 3D29; -.
DR PDBsum; 3DY3; -.
DR PDBsum; 3DY4; -.
DR PDBsum; 3E47; -.
DR PDBsum; 3GPJ; -.
DR PDBsum; 3GPT; -.
DR PDBsum; 3GPW; -.
DR PDBsum; 3HYE; -.
DR PDBsum; 3JCO; -.
DR PDBsum; 3JCP; -.
DR PDBsum; 3MG0; -.
DR PDBsum; 3MG4; -.
DR PDBsum; 3MG6; -.
DR PDBsum; 3MG7; -.
DR PDBsum; 3MG8; -.
DR PDBsum; 3NZJ; -.
DR PDBsum; 3NZW; -.
DR PDBsum; 3NZX; -.
DR PDBsum; 3OEU; -.
DR PDBsum; 3OEV; -.
DR PDBsum; 3OKJ; -.
DR PDBsum; 3SDI; -.
DR PDBsum; 3SDK; -.
DR PDBsum; 3SHJ; -.
DR PDBsum; 3TDD; -.
DR PDBsum; 3UN4; -.
DR PDBsum; 3UN8; -.
DR PDBsum; 3WXR; -.
DR PDBsum; 4CR2; -.
DR PDBsum; 4CR3; -.
DR PDBsum; 4CR4; -.
DR PDBsum; 4EU2; -.
DR PDBsum; 4FZC; -.
DR PDBsum; 4FZG; -.
DR PDBsum; 4G4S; -.
DR PDBsum; 4GK7; -.
DR PDBsum; 4HNP; -.
DR PDBsum; 4HRC; -.
DR PDBsum; 4HRD; -.
DR PDBsum; 4INR; -.
DR PDBsum; 4INT; -.
DR PDBsum; 4INU; -.
DR PDBsum; 4J70; -.
DR PDBsum; 4JSQ; -.
DR PDBsum; 4JSU; -.
DR PDBsum; 4JT0; -.
DR PDBsum; 4LQI; -.
DR PDBsum; 4LTC; -.
DR PDBsum; 4NNN; -.
DR PDBsum; 4NNW; -.
DR PDBsum; 4NO1; -.
DR PDBsum; 4NO6; -.
DR PDBsum; 4NO8; -.
DR PDBsum; 4NO9; -.
DR PDBsum; 4Q1S; -.
DR PDBsum; 4QBY; -.
DR PDBsum; 4QLQ; -.
DR PDBsum; 4QLS; -.
DR PDBsum; 4QLT; -.
DR PDBsum; 4QLU; -.
DR PDBsum; 4QLV; -.
DR PDBsum; 4QUX; -.
DR PDBsum; 4QUY; -.
DR PDBsum; 4QV0; -.
DR PDBsum; 4QV1; -.
DR PDBsum; 4QV3; -.
DR PDBsum; 4QV4; -.
DR PDBsum; 4QV5; -.
DR PDBsum; 4QV6; -.
DR PDBsum; 4QV7; -.
DR PDBsum; 4QV8; -.
DR PDBsum; 4QV9; -.
DR PDBsum; 4QVL; -.
DR PDBsum; 4QVM; -.
DR PDBsum; 4QVN; -.
DR PDBsum; 4QVP; -.
DR PDBsum; 4QVQ; -.
DR PDBsum; 4QVV; -.
DR PDBsum; 4QVW; -.
DR PDBsum; 4QVY; -.
DR PDBsum; 4QW0; -.
DR PDBsum; 4QW1; -.
DR PDBsum; 4QW3; -.
DR PDBsum; 4QW4; -.
DR PDBsum; 4QW5; -.
DR PDBsum; 4QW6; -.
DR PDBsum; 4QW7; -.
DR PDBsum; 4QWF; -.
DR PDBsum; 4QWG; -.
DR PDBsum; 4QWI; -.
DR PDBsum; 4QWJ; -.
DR PDBsum; 4QWK; -.
DR PDBsum; 4QWL; -.
DR PDBsum; 4QWR; -.
DR PDBsum; 4QWS; -.
DR PDBsum; 4QWU; -.
DR PDBsum; 4QWX; -.
DR PDBsum; 4QXJ; -.
DR PDBsum; 4QZ0; -.
DR PDBsum; 4QZ1; -.
DR PDBsum; 4QZ2; -.
DR PDBsum; 4QZ3; -.
DR PDBsum; 4QZ4; -.
DR PDBsum; 4QZ5; -.
DR PDBsum; 4QZ6; -.
DR PDBsum; 4QZ7; -.
DR PDBsum; 4QZW; -.
DR PDBsum; 4QZX; -.
DR PDBsum; 4QZZ; -.
DR PDBsum; 4R00; -.
DR PDBsum; 4R02; -.
DR PDBsum; 4R17; -.
DR PDBsum; 4R18; -.
DR PDBsum; 4RUR; -.
DR PDBsum; 4V7O; -.
DR PDBsum; 4X6Z; -.
DR PDBsum; 4Y69; -.
DR PDBsum; 4Y6A; -.
DR PDBsum; 4Y6V; -.
DR PDBsum; 4Y6Z; -.
DR PDBsum; 4Y70; -.
DR PDBsum; 4Y74; -.
DR PDBsum; 4Y75; -.
DR PDBsum; 4Y77; -.
DR PDBsum; 4Y78; -.
DR PDBsum; 4Y7W; -.
DR PDBsum; 4Y7X; -.
DR PDBsum; 4Y7Y; -.
DR PDBsum; 4Y80; -.
DR PDBsum; 4Y81; -.
DR PDBsum; 4Y82; -.
DR PDBsum; 4Y84; -.
DR PDBsum; 4Y8G; -.
DR PDBsum; 4Y8H; -.
DR PDBsum; 4Y8I; -.
DR PDBsum; 4Y8J; -.
DR PDBsum; 4Y8K; -.
DR PDBsum; 4Y8L; -.
DR PDBsum; 4Y8M; -.
DR PDBsum; 4Y8N; -.
DR PDBsum; 4Y8O; -.
DR PDBsum; 4Y8P; -.
DR PDBsum; 4Y8Q; -.
DR PDBsum; 4Y8R; -.
DR PDBsum; 4Y8S; -.
DR PDBsum; 4Y8T; -.
DR PDBsum; 4Y8U; -.
DR PDBsum; 4Y9Y; -.
DR PDBsum; 4Y9Z; -.
DR PDBsum; 4YA0; -.
DR PDBsum; 4YA1; -.
DR PDBsum; 4YA2; -.
DR PDBsum; 4YA3; -.
DR PDBsum; 4YA4; -.
DR PDBsum; 4YA5; -.
DR PDBsum; 4YA7; -.
DR PDBsum; 4YA9; -.
DR PDBsum; 4Z1L; -.
DR PDBsum; 5A5B; -.
DR PDBsum; 5AHJ; -.
DR PDBsum; 5BOU; -.
DR PDBsum; 5BXL; -.
DR PDBsum; 5BXN; -.
DR PDBsum; 5CGF; -.
DR PDBsum; 5CGG; -.
DR PDBsum; 5CGH; -.
DR PDBsum; 5CGI; -.
DR PDBsum; 5CZ4; -.
DR PDBsum; 5CZ5; -.
DR PDBsum; 5CZ6; -.
DR PDBsum; 5CZ7; -.
DR PDBsum; 5CZ8; -.
DR PDBsum; 5CZ9; -.
DR PDBsum; 5CZA; -.
DR PDBsum; 5D0S; -.
DR PDBsum; 5D0T; -.
DR PDBsum; 5D0V; -.
DR PDBsum; 5D0W; -.
DR PDBsum; 5D0X; -.
DR PDBsum; 5D0Z; -.
DR PDBsum; 5DKI; -.
DR PDBsum; 5DKJ; -.
DR PDBsum; 5FG7; -.
DR PDBsum; 5FG9; -.
DR PDBsum; 5FGA; -.
DR PDBsum; 5FGD; -.
DR PDBsum; 5FGE; -.
DR PDBsum; 5FGF; -.
DR PDBsum; 5FGG; -.
DR PDBsum; 5FGH; -.
DR PDBsum; 5FGI; -.
DR PDBsum; 5FHS; -.
DR PDBsum; 5JHR; -.
DR PDBsum; 5JHS; -.
DR PDBsum; 5L52; -.
DR PDBsum; 5L54; -.
DR PDBsum; 5L55; -.
DR PDBsum; 5L5A; -.
DR PDBsum; 5L5B; -.
DR PDBsum; 5L5D; -.
DR PDBsum; 5L5E; -.
DR PDBsum; 5L5F; -.
DR PDBsum; 5L5H; -.
DR PDBsum; 5L5I; -.
DR PDBsum; 5L5J; -.
DR PDBsum; 5L5O; -.
DR PDBsum; 5L5P; -.
DR PDBsum; 5L5Q; -.
DR PDBsum; 5L5R; -.
DR PDBsum; 5L5S; -.
DR PDBsum; 5L5T; -.
DR PDBsum; 5L5U; -.
DR PDBsum; 5L5V; -.
DR PDBsum; 5L5W; -.
DR PDBsum; 5L5X; -.
DR PDBsum; 5L5Y; -.
DR PDBsum; 5L5Z; -.
DR PDBsum; 5L60; -.
DR PDBsum; 5L61; -.
DR PDBsum; 5L62; -.
DR PDBsum; 5L63; -.
DR PDBsum; 5L64; -.
DR PDBsum; 5L65; -.
DR PDBsum; 5L66; -.
DR PDBsum; 5L67; -.
DR PDBsum; 5L68; -.
DR PDBsum; 5L69; -.
DR PDBsum; 5L6A; -.
DR PDBsum; 5L6B; -.
DR PDBsum; 5L6C; -.
DR PDBsum; 5LAI; -.
DR PDBsum; 5LAJ; -.
DR PDBsum; 5LTT; -.
DR PDBsum; 5M2B; -.
DR PDBsum; 5MP9; -.
DR PDBsum; 5MPA; -.
DR PDBsum; 5MPB; -.
DR PDBsum; 5MPC; -.
DR PDBsum; 5NIF; -.
DR PDBsum; 5WVI; -.
DR PDBsum; 5WVK; -.
DR PDBsum; 6EF3; -.
DR PDBsum; 6FVT; -.
DR PDBsum; 6FVU; -.
DR PDBsum; 6FVV; -.
DR PDBsum; 6FVW; -.
DR PDBsum; 6FVX; -.
DR PDBsum; 6FVY; -.
DR PDBsum; 6G7F; -.
DR PDBsum; 6G8M; -.
DR PDBsum; 6G8N; -.
DR PDBsum; 6GOP; -.
DR PDBsum; 6H39; -.
DR PDBsum; 6HTB; -.
DR PDBsum; 6HTC; -.
DR PDBsum; 6HTD; -.
DR PDBsum; 6HTP; -.
DR PDBsum; 6HTR; -.
DR PDBsum; 6HUB; -.
DR PDBsum; 6HUC; -.
DR PDBsum; 6HUQ; -.
DR PDBsum; 6HUU; -.
DR PDBsum; 6HUV; -.
DR PDBsum; 6HV3; -.
DR PDBsum; 6HV4; -.
DR PDBsum; 6HV5; -.
DR PDBsum; 6HV7; -.
DR PDBsum; 6HVA; -.
DR PDBsum; 6HVR; -.
DR PDBsum; 6HVS; -.
DR PDBsum; 6HVT; -.
DR PDBsum; 6HVU; -.
DR PDBsum; 6HVV; -.
DR PDBsum; 6HVW; -.
DR PDBsum; 6HVX; -.
DR PDBsum; 6HVY; -.
DR PDBsum; 6HW0; -.
DR PDBsum; 6HW3; -.
DR PDBsum; 6HW4; -.
DR PDBsum; 6HW5; -.
DR PDBsum; 6HW6; -.
DR PDBsum; 6HW7; -.
DR PDBsum; 6HW8; -.
DR PDBsum; 6HW9; -.
DR PDBsum; 6HWA; -.
DR PDBsum; 6HWB; -.
DR PDBsum; 6HWC; -.
DR PDBsum; 6HWD; -.
DR PDBsum; 6HWE; -.
DR PDBsum; 6HWF; -.
DR PDBsum; 6J2C; -.
DR PDBsum; 6J2N; -.
DR PDBsum; 6J2Q; -.
DR PDBsum; 6J2X; -.
DR PDBsum; 6J30; -.
DR PDBsum; 6ZOU; -.
DR PDBsum; 6ZP6; -.
DR PDBsum; 6ZP8; -.
DR PDBsum; 7LS5; -.
DR PDBsum; 7O2L; -.
DR PDBsum; 7QO3; -.
DR PDBsum; 7QO5; -.
DR AlphaFoldDB; P30657; -.
DR SMR; P30657; -.
DR BioGRID; 31208; 427.
DR ComplexPortal; CPX-2262; 26S Proteasome complex.
DR DIP; DIP-2807N; -.
DR IntAct; P30657; 20.
DR MINT; P30657; -.
DR STRING; 4932.YFR050C; -.
DR MEROPS; T01.A13; -.
DR iPTMnet; P30657; -.
DR MaxQB; P30657; -.
DR PaxDb; P30657; -.
DR PRIDE; P30657; -.
DR EnsemblFungi; YFR050C_mRNA; YFR050C; YFR050C.
DR GeneID; 850611; -.
DR KEGG; sce:YFR050C; -.
DR SGD; S000001946; PRE4.
DR VEuPathDB; FungiDB:YFR050C; -.
DR eggNOG; KOG0185; Eukaryota.
DR GeneTree; ENSGT00390000000698; -.
DR HOGENOM; CLU_072435_0_1_1; -.
DR InParanoid; P30657; -.
DR OMA; KGYGTQT; -.
DR BioCyc; YEAST:G3O-30496-MON; -.
DR Reactome; R-SCE-1236978; Cross-presentation of soluble exogenous antigens (endosomes).
DR Reactome; R-SCE-382556; ABC-family proteins mediated transport.
DR Reactome; R-SCE-5668541; TNFR2 non-canonical NF-kB pathway.
DR Reactome; R-SCE-5687128; MAPK6/MAPK4 signaling.
DR Reactome; R-SCE-5689880; Ub-specific processing proteases.
DR Reactome; R-SCE-68949; Orc1 removal from chromatin.
DR Reactome; R-SCE-69017; CDK-mediated phosphorylation and removal of Cdc6.
DR Reactome; R-SCE-69601; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
DR Reactome; R-SCE-75815; Ubiquitin-dependent degradation of Cyclin D.
DR Reactome; R-SCE-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis.
DR Reactome; R-SCE-8948751; Regulation of PTEN stability and activity.
DR Reactome; R-SCE-8951664; Neddylation.
DR Reactome; R-SCE-9755511; KEAP1-NFE2L2 pathway.
DR Reactome; R-SCE-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR EvolutionaryTrace; P30657; -.
DR PRO; PR:P30657; -.
DR Proteomes; UP000002311; Chromosome VI.
DR RNAct; P30657; protein.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IC:SGD.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
DR GO; GO:0000502; C:proteasome complex; IPI:ComplexPortal.
DR GO; GO:0005839; C:proteasome core complex; IBA:GO_Central.
DR GO; GO:0019774; C:proteasome core complex, beta-subunit complex; IDA:SGD.
DR GO; GO:0034515; C:proteasome storage granule; IDA:SGD.
DR GO; GO:0010498; P:proteasomal protein catabolic process; IBA:GO_Central.
DR GO; GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
DR GO; GO:0043248; P:proteasome assembly; IGI:SGD.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IDA:SGD.
DR CDD; cd03760; proteasome_beta_type_4; 1.
DR Gene3D; 3.60.20.10; -; 1.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR InterPro; IPR016295; Proteasome_beta4.
DR InterPro; IPR016050; Proteasome_bsu_CS.
DR InterPro; IPR001353; Proteasome_sua/b.
DR InterPro; IPR023333; Proteasome_suB-type.
DR PANTHER; PTHR11599:SF5; PTHR11599:SF5; 1.
DR Pfam; PF00227; Proteasome; 1.
DR PIRSF; PIRSF001213; Psome_endopept_beta; 1.
DR SUPFAM; SSF56235; SSF56235; 1.
DR PROSITE; PS00854; PROTEASOME_BETA_1; 1.
DR PROSITE; PS51476; PROTEASOME_BETA_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Nucleus; Proteasome; Reference proteome.
FT PROPEP 1..33
FT /id="PRO_0000331490"
FT CHAIN 34..266
FT /note="Proteasome subunit beta type-7"
FT /id="PRO_0000148073"
FT CONFLICT 188
FT /note="L -> V (in Ref. 5; AAT92966)"
FT /evidence="ECO:0000305"
FT STRAND 39..41
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 44..49
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 52..58
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 61..63
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 66..70
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 75..78
FT /evidence="ECO:0007829|PDB:1RYP"
FT TURN 79..81
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 82..89
FT /evidence="ECO:0007829|PDB:1RYP"
FT HELIX 90..108
FT /evidence="ECO:0007829|PDB:1RYP"
FT TURN 112..118
FT /evidence="ECO:0007829|PDB:1RYP"
FT HELIX 122..138
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 145..152
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 158..164
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 169..171
FT /evidence="ECO:0007829|PDB:4QVP"
FT STRAND 173..176
FT /evidence="ECO:0007829|PDB:1RYP"
FT HELIX 179..188
FT /evidence="ECO:0007829|PDB:1RYP"
FT TURN 189..191
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 192..194
FT /evidence="ECO:0007829|PDB:3GPJ"
FT HELIX 195..200
FT /evidence="ECO:0007829|PDB:1RYP"
FT HELIX 203..220
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 226..234
FT /evidence="ECO:0007829|PDB:1RYP"
FT TURN 235..237
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 238..246
FT /evidence="ECO:0007829|PDB:1RYP"
FT HELIX 253..257
FT /evidence="ECO:0007829|PDB:1RYP"
FT STRAND 260..263
FT /evidence="ECO:0007829|PDB:1RYP"
SQ SEQUENCE 266 AA; 29443 MW; E585BB3B5D0C8E2C CRC64;
MNHDPFSWGR PADSTYGAYN TQIANAGASP MVNTQQPIVT GTSVISMKYD NGVIIAADNL
GSYGSLLRFN GVERLIPVGD NTVVGISGDI SDMQHIERLL KDLVTENAYD NPLADAEEAL
EPSYIFEYLA TVMYQRRSKM NPLWNAIIVA GVQSNGDQFL RYVNLLGVTY SSPTLATGFG
AHMANPLLRK VVDRESDIPK TTVQVAEEAI VNAMRVLYYR DARSSRNFSL AIIDKNTGLT
FKKNLQVENM KWDFAKDIKG YGTQKI
