ATG8L_DICDI
ID ATG8L_DICDI Reviewed; 126 AA.
AC Q54G11;
DT 24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Autophagy-related protein 8-like protein DDB_G0290491;
DE Flags: Precursor;
GN ORFNames=DDB_G0290491;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Lipid-anchor
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ATG8 family. {ECO:0000305}.
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DR EMBL; AAFI02000164; EAL62106.1; -; Genomic_DNA.
DR RefSeq; XP_635606.1; XM_630514.1.
DR AlphaFoldDB; Q54G11; -.
DR SMR; Q54G11; -.
DR STRING; 44689.DDB0238851; -.
DR PaxDb; Q54G11; -.
DR EnsemblProtists; EAL62106; EAL62106; DDB_G0290491.
DR GeneID; 8627678; -.
DR KEGG; ddi:DDB_G0290491; -.
DR dictyBase; DDB_G0290491; atg8b.
DR eggNOG; KOG1654; Eukaryota.
DR HOGENOM; CLU_119276_0_1_1; -.
DR InParanoid; Q54G11; -.
DR OMA; AKMKWMF; -.
DR PhylomeDB; Q54G11; -.
DR Reactome; R-DDI-1632852; Macroautophagy.
DR Reactome; R-DDI-8854214; TBC/RABGAPs.
DR Reactome; R-DDI-8934903; Receptor Mediated Mitophagy.
DR Reactome; R-DDI-9664873; Pexophagy.
DR Reactome; R-DDI-9755511; KEAP1-NFE2L2 pathway.
DR PRO; PR:Q54G11; -.
DR Proteomes; UP000002195; Chromosome 5.
DR GO; GO:0005776; C:autophagosome; IDA:dictyBase.
DR GO; GO:0000421; C:autophagosome membrane; IDA:dictyBase.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0097352; P:autophagosome maturation; IMP:dictyBase.
DR GO; GO:0006995; P:cellular response to nitrogen starvation; IBA:GO_Central.
DR GO; GO:0016236; P:macroautophagy; IBA:GO_Central.
DR GO; GO:0009617; P:response to bacterium; HEP:dictyBase.
DR InterPro; IPR004241; Atg8-like.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR10969; PTHR10969; 1.
DR Pfam; PF02991; ATG8; 1.
DR SUPFAM; SSF54236; SSF54236; 1.
PE 3: Inferred from homology;
KW Lipoprotein; Membrane; Reference proteome.
FT CHAIN 1..123
FT /note="Autophagy-related protein 8-like protein
FT DDB_G0290491"
FT /id="PRO_0000388778"
FT PROPEP 124..126
FT /note="Removed in mature form"
FT /evidence="ECO:0000250"
FT /id="PRO_0000388779"
FT LIPID 123
FT /note="Phosphatidylethanolamine amidated glycine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 126 AA; 14573 MW; DAEBAB47172512B1 CRC64;
MALLSKSFKQ EYSLEKRKLI SSKIRNRYKD RLPIIVERAA NSDVPDINKK KFLAPSNMVI
TNFIMEIRKH LDDSDHNEQK AIFLFVNKNN LPPSSQLLSS IYDAHKDEDG FLYICYSGEN
TFGSDI