ID   ATGA1_DANRE             Reviewed;         218 AA.
AC   Q3B736;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Autophagy-related protein 101;
GN   Name=atg101; ORFNames=zgc:123177;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Autophagy factor required for autophagosome formation.
CC       {ECO:0000250|UniProtKB:Q9BSB4}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9BSB4}.
CC       Preautophagosomal structure {ECO:0000250|UniProtKB:Q9BSB4}. Note=Under
CC       starvation conditions, it is localized to puncate structures primarily
CC       representing the isolation membrane; the isolation membrane sequesters
CC       a portion of the cytoplasm resulting in autophagosome formation.
CC       {ECO:0000250|UniProtKB:Q9BSB4}.
CC   -!- SIMILARITY: Belongs to the ATG101 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC107836; AAI07837.1; -; mRNA.
DR   RefSeq; NP_001032316.1; NM_001037239.1.
DR   AlphaFoldDB; Q3B736; -.
DR   SMR; Q3B736; -.
DR   STRING; 7955.ENSDARP00000063543; -.
DR   PaxDb; Q3B736; -.
DR   Ensembl; ENSDART00000063544; ENSDARP00000063543; ENSDARG00000043287.
DR   Ensembl; ENSDART00000126727; ENSDARP00000106121; ENSDARG00000043287.
DR   Ensembl; ENSDART00000141013; ENSDARP00000122195; ENSDARG00000043287.
DR   GeneID; 567680; -.
DR   KEGG; dre:567680; -.
DR   CTD; 60673; -.
DR   ZFIN; ZDB-GENE-051030-36; atg101.
DR   eggNOG; KOG4493; Eukaryota.
DR   GeneTree; ENSGT00390000016511; -.
DR   HOGENOM; CLU_110397_0_0_1; -.
DR   InParanoid; Q3B736; -.
DR   OrthoDB; 1539728at2759; -.
DR   PhylomeDB; Q3B736; -.
DR   TreeFam; TF320996; -.
DR   Reactome; R-DRE-1632852; Macroautophagy.
DR   PRO; PR:Q3B736; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 10.
DR   Bgee; ENSDARG00000043287; Expressed in mature ovarian follicle and 27 other tissues.
DR   GO; GO:0000407; C:phagophore assembly site; IBA:GO_Central.
DR   GO; GO:0000045; P:autophagosome assembly; IBA:GO_Central.
DR   InterPro; IPR012445; ATG101.
DR   PANTHER; PTHR13292; PTHR13292; 1.
DR   Pfam; PF07855; ATG101; 1.
PE   2: Evidence at transcript level;
KW   Autophagy; Cytoplasm; Reference proteome.
FT   CHAIN           1..218
FT                   /note="Autophagy-related protein 101"
FT                   /id="PRO_0000294325"
SQ   SEQUENCE   218 AA;  24906 MW;  5925DC292F50FD4C CRC64;
     MNCRSEVLEV SVEGRQVDEA MLGLLHTILL HRSTGKFHYK KEGTYSIGTV GTQDVDCDFI
     DFTFVRVSSD ELDRVIRKAV AEFKDALGNS GSDGMGQISL EFYQKKKSRW PFSDECIPWE
     VWSIKVNVVN LANEQERQIC REKVGEKLGE KVINIVEVIN RHEYLPKMPT QSEVDNVFDT
     SLKDVQPYLY KITYQITDSL GTSVSTTMRR LIKDTLAL