ID   ATGA1_XENLA             Reviewed;         218 AA.
AC   Q6DE58;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Autophagy-related protein 101;
GN   Name=atg101;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Autophagy factor required for autophagosome formation.
CC       {ECO:0000250|UniProtKB:Q9BSB4}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9BSB4}.
CC       Preautophagosomal structure {ECO:0000250|UniProtKB:Q9BSB4}. Note=Under
CC       starvation conditions, it is localized to puncate structures primarily
CC       representing the isolation membrane; the isolation membrane sequesters
CC       a portion of the cytoplasm resulting in autophagosome formation.
CC       {ECO:0000250|UniProtKB:Q9BSB4}.
CC   -!- SIMILARITY: Belongs to the ATG101 family. {ECO:0000305}.
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DR   EMBL; BC077284; AAH77284.1; -; mRNA.
DR   RefSeq; NP_001086669.1; NM_001093200.1.
DR   AlphaFoldDB; Q6DE58; -.
DR   SMR; Q6DE58; -.
DR   DNASU; 446504; -.
DR   GeneID; 446504; -.
DR   KEGG; xla:446504; -.
DR   CTD; 446504; -.
DR   Xenbase; XB-GENE-5873876; atg101.L.
DR   OMA; PWEVWNL; -.
DR   OrthoDB; 1539728at2759; -.
DR   Proteomes; UP000186698; Chromosome 2L.
DR   Bgee; 446504; Expressed in muscle tissue and 19 other tissues.
DR   GO; GO:0000407; C:phagophore assembly site; IEA:UniProtKB-SubCell.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   InterPro; IPR012445; ATG101.
DR   PANTHER; PTHR13292; PTHR13292; 1.
DR   Pfam; PF07855; ATG101; 1.
PE   2: Evidence at transcript level;
KW   Autophagy; Cytoplasm; Reference proteome.
FT   CHAIN           1..218
FT                   /note="Autophagy-related protein 101"
FT                   /id="PRO_0000294326"
SQ   SEQUENCE   218 AA;  25048 MW;  1B3EFB14D699D4BE CRC64;
     MNCRSEILEV SVEGRQVEEA MLAVLHTILL HRSTGKFHYK KEGTYSIGTV GTQDIDCDFI
     EFTYVRVSSE ELDRALHKAV SEFKDALRNS GSDGIGQVSL EFYQKKKSRW PFSDECIPWE
     VWTIKVNVVS LANEQERQIC REKVGEKLGE KIINIVEVMN RHEYLPKMPT QSEVDNVFDT
     SLKDVQPYLY KISYQITDSL GTSVTTTMRR LIKDTLAL