ID   ATGA1_XENTR             Reviewed;         218 AA.
AC   A4IH75;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=Autophagy-related protein 101;
GN   Name=atg101;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Autophagy factor required for autophagosome formation.
CC       {ECO:0000250|UniProtKB:Q9BSB4}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9BSB4}.
CC       Preautophagosomal structure {ECO:0000250|UniProtKB:Q9BSB4}. Note=Under
CC       starvation conditions, it is localized to puncate structures primarily
CC       representing the isolation membrane; the isolation membrane sequesters
CC       a portion of the cytoplasm resulting in autophagosome formation.
CC       {ECO:0000250|UniProtKB:Q9BSB4}.
CC   -!- SIMILARITY: Belongs to the ATG101 family. {ECO:0000305}.
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DR   EMBL; BC135403; AAI35404.1; -; mRNA.
DR   RefSeq; NP_001016820.1; NM_001016820.2.
DR   AlphaFoldDB; A4IH75; -.
DR   SMR; A4IH75; -.
DR   DNASU; 549574; -.
DR   GeneID; 549574; -.
DR   KEGG; xtr:549574; -.
DR   CTD; 60673; -.
DR   Xenbase; XB-GENE-5873849; atg101.
DR   InParanoid; A4IH75; -.
DR   OrthoDB; 1539728at2759; -.
DR   Reactome; R-XTR-1632852; Macroautophagy.
DR   Proteomes; UP000008143; Chromosome 2.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0000407; C:phagophore assembly site; IBA:GO_Central.
DR   GO; GO:0000045; P:autophagosome assembly; IBA:GO_Central.
DR   InterPro; IPR012445; ATG101.
DR   PANTHER; PTHR13292; PTHR13292; 1.
DR   Pfam; PF07855; ATG101; 1.
PE   2: Evidence at transcript level;
KW   Autophagy; Cytoplasm; Reference proteome.
FT   CHAIN           1..218
FT                   /note="Autophagy-related protein 101"
FT                   /id="PRO_0000294327"
SQ   SEQUENCE   218 AA;  25001 MW;  D096214AAF7C7421 CRC64;
     MNCRSEVLEV SVEGRQVEEA VLAVLHTILL HRSTGKFHYK KEGTYSIGTV GTQDIDCDFI
     EFTYVRVSSE ELDRALHKAV SEFKDALRNS GSDGIGQVSL EFYQKKKSRW PFSDECIPWE
     VWTIKVNVVS LANEQERQIC REKVGEKLGE KIINIVEVMN RHEYLPKMPT QSEVDNVFDT
     SLKDVQPYLY KISYQITDSL GTSVTTTMRR LIKDTLAL