ID   ATI2_PSHV1              Reviewed;         607 AA.
AC   Q6UDL7;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   23-FEB-2022, entry version 43.
DE   RecName: Full=Alpha trans-inducing factor;
DE   AltName: Full=Tegument protein UL46;
DE   AltName: Full=Tegument protein VP11/12;
GN   Name=UL46;
OS   Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1)
OS   (Pacheco's disease virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Iltovirus.
OX   NCBI_TaxID=670426;
OH   NCBI_TaxID=152276; Amazona oratrix (yellow-headed parrot).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16873243; DOI=10.1128/jvi.00134-06;
RA   Thureen D.R., Keeler C.L. Jr.;
RT   "Psittacid herpesvirus 1 and infectious laryngotracheitis virus:
RT   Comparative genome sequence analysis of two avian alphaherpesviruses.";
RL   J. Virol. 80:7863-7872(2006).
CC   -!- FUNCTION: Abundant tegument protein. Trans-activates the immediate
CC       early genes (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250}. Host cell membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae HHV-1 VP11/12 protein family.
CC       {ECO:0000305}.
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DR   EMBL; AY372243; AAQ73693.1; -; Genomic_DNA.
DR   Proteomes; UP000006840; Genome.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR005051; Herpes_UL46.
DR   Pfam; PF03387; Herpes_UL46; 1.
PE   3: Inferred from homology;
KW   Activator; Host cell membrane; Host membrane; Membrane; Reference proteome;
KW   Transcription; Transcription regulation; Virion; Virion tegument.
FT   CHAIN           1..607
FT                   /note="Alpha trans-inducing factor"
FT                   /id="PRO_0000406856"
FT   REGION          473..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          557..607
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        484..499
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        501..521
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        523..540
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   607 AA;  67233 MW;  8D7663E4A5AD144E CRC64;
     MSTKSSPARG TVYIPGHAMT LRSVELKKIP IKVLKTVFEN AQKISPVWSL EQASLNSLAA
     TAETMLPGPI LGPSRAEHFN GPDPTIPDKM VVRMVEGDHK MLFRATLDDT YHILVTRIRV
     REKFVQRLAR AMYTRRASML MDVELPFKDK MEGVYAAADL EAICKMHYWV FPHTVPAPNM
     KSPDDKAYLT SVAQFARSTK FIESYMYYMR PHDPEVNSTD TGNRVAAMLI YIHGMQCKLA
     SLFDALDAAI LRSKFNAGSR GHSLSGIYGF TRNGKGTMMA AKSSGNVVEQ IRRTCPFGSD
     AMVECLISAL DRMTYLVARW ELMSVDKRDD AKAAIAAGMG LAWLLNGHLS YLTNMIMTVY
     VLWLPEHYLN PRLILTISSR VLLGQLLCTS HTTFRENATC PKMLLAQNAV EWKKQERGTA
     AWLDYVCARA WLRASRENRK PANITAMNNT LEEISAHVLK ILEEAPQPAA SAPSSLCATN
     YCPDSPPSRP PPPPPVQKRA KDPGRFSRIM AGDDRRASVQ SREDGSGYMT CEHTASTSTK
     LRGRVLSAPL IRHRRKSAEG LQGAAKLRGG SLRLPDNGGR AALPSEPPPS SESTDTSPEA
     RPETDHK