ID   ATIF2_CAEBR             Reviewed;         109 AA.
AC   A8XZB0;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=ATPase inhibitor mai-2, mitochondrial {ECO:0000305};
DE   AltName: Full=ATP synthase F1 subunit epsilon {ECO:0000250|UniProtKB:Q9UII2};
DE   Flags: Precursor;
GN   Name=mai-2 {ECO:0000312|EMBL:CAP37977.1}; ORFNames=CBG21048;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1] {ECO:0000312|EMBL:CAP37977.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000312|EMBL:CAP37977.1};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Thought to be a regulatory component of the ATP-synthesizing
CC       complex in the mitochondria. {ECO:0000250|UniProtKB:O44441}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the ATPase inhibitor family. {ECO:0000255}.
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DR   EMBL; HE601035; CAP37977.1; -; Genomic_DNA.
DR   RefSeq; XP_002634729.1; XM_002634683.1.
DR   AlphaFoldDB; A8XZB0; -.
DR   SMR; A8XZB0; -.
DR   STRING; 6238.CBG21048; -.
DR   EnsemblMetazoa; CBG21048.1; CBG21048.1; WBGene00039929.
DR   GeneID; 8576722; -.
DR   KEGG; cbr:CBG_21048; -.
DR   CTD; 8576722; -.
DR   WormBase; CBG21048; CBP05003; WBGene00039929; Cbr-mai-2.
DR   eggNOG; ENOG502S8MH; Eukaryota.
DR   HOGENOM; CLU_147479_1_2_1; -.
DR   InParanoid; A8XZB0; -.
DR   OMA; QEVDHHK; -.
DR   OrthoDB; 1596356at2759; -.
DR   Proteomes; UP000008549; Chromosome IV.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0051117; F:ATPase binding; IBA:GO_Central.
DR   GO; GO:0042030; F:ATPase inhibitor activity; IBA:GO_Central.
DR   GO; GO:0006783; P:heme biosynthetic process; IBA:GO_Central.
DR   GO; GO:0032780; P:negative regulation of ATP-dependent activity; IBA:GO_Central.
DR   InterPro; IPR007648; ATPase_inhibitor_mt.
DR   Pfam; PF04568; IATP; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250|UniProtKB:O44441"
FT   CHAIN           ?..109
FT                   /note="ATPase inhibitor mai-2, mitochondrial"
FT                   /id="PRO_0000351212"
FT   REGION          17..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          73..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          45..109
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   109 AA;  12045 MW;  24792563C7D17AE8 CRC64;
     MLSVSRVASR MTGVVARFST GGHGDGAGRG GGSGGSIRDA GGAFGKMEAA REDEYFYKKQ
     KAQLEELRKH IQQEVDHHKS QLENHQKVLD RHQKRISEIE AEERALGKE