ID   ATIF_SCHPO              Reviewed;          90 AA.
AC   O74523;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 121.
DE   RecName: Full=Putative ATPase inhibitor, mitochondrial {ECO:0000305};
DE   AltName: Full=ATP synthase F1 subunit epsilon {ECO:0000250|UniProtKB:Q9UII2};
DE   Flags: Precursor;
GN   Name=inh1; ORFNames=SPCC70.02c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Forms a one-to-one complex with ATPase to inhibit the enzyme
CC       activity completely. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATPase inhibitor family. {ECO:0000305}.
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DR   EMBL; CU329672; CAA19352.1; -; Genomic_DNA.
DR   PIR; T41548; T41548.
DR   RefSeq; NP_588536.1; NM_001023524.2.
DR   AlphaFoldDB; O74523; -.
DR   SMR; O74523; -.
DR   BioGRID; 276086; 4.
DR   STRING; 4896.SPCC70.02c.1; -.
DR   MaxQB; O74523; -.
DR   PaxDb; O74523; -.
DR   EnsemblFungi; SPCC70.02c.1; SPCC70.02c.1:pep; SPCC70.02c.
DR   GeneID; 2539524; -.
DR   KEGG; spo:SPCC70.02c; -.
DR   PomBase; SPCC70.02c; inh1.
DR   VEuPathDB; FungiDB:SPCC70.02c; -.
DR   HOGENOM; CLU_2442132_0_0_1; -.
DR   InParanoid; O74523; -.
DR   OMA; KENQFIH; -.
DR   PhylomeDB; O74523; -.
DR   PRO; PR:O74523; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005739; C:mitochondrion; ISO:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0042030; F:ATPase inhibitor activity; ISO:PomBase.
DR   GO; GO:0032780; P:negative regulation of ATP-dependent activity; IEA:InterPro.
DR   GO; GO:1905707; P:negative regulation of mitochondrial ATP synthesis coupled proton transport; ISO:PomBase.
DR   InterPro; IPR007648; ATPase_inhibitor_mt.
DR   Pfam; PF04568; IATP; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT   CHAIN           ?..90
FT                   /note="Putative ATPase inhibitor, mitochondrial"
FT                   /id="PRO_0000002553"
FT   COILED          42..89
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   90 AA;  10674 MW;  F4C4DF852E3E6909 CRC64;
     MYKYCFRKPA CISYRGIRFM SKASDTDPTL ANASSAKRSA FESREKAKED FFVHQHEIEQ
     LRKLKESLKL HREELDELES RVDKKMKSNE