ATL28_ARATH
ID ATL28_ARATH Reviewed; 254 AA.
AC Q6NKR1; O82298;
DT 05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=RING-H2 finger protein ATL28;
DE EC=2.3.2.27 {ECO:0000305};
DE AltName: Full=RING-type E3 ubiquitin transferase ATL28 {ECO:0000305};
GN Name=ATL28; OrderedLocusNames=At2g35420; ORFNames=T32F12.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Carninci P., Hayashizaki Y.,
RA Ishida J., Kamiya A., Kawai J., Narusaka M., Sakurai T., Satou M., Seki M.,
RA Shinozaki K., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY ORGANIZATION.
RX PubMed=11983057; DOI=10.1186/gb-2002-3-4-research0016;
RA Kosarev P., Mayer K.F.X., Hardtke C.S.;
RT "Evaluation and classification of RING-finger domains encoded by the
RT Arabidopsis genome.";
RL Genome Biol. 3:RESEARCH0016.1-RESEARCH0016.12(2002).
RN [5]
RP NOMENCLATURE, AND GENE FAMILY ORGANIZATION.
RX PubMed=16557337; DOI=10.1007/s00239-005-0038-y;
RA Serrano M., Parra S., Alcaraz L.D., Guzman P.;
RT "The ATL gene family from Arabidopsis thaliana and Oryza sativa comprises a
RT large number of putative ubiquitin ligases of the RING-H2 type.";
RL J. Mol. Evol. 62:434-445(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000305};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- DOMAIN: The RING-type zinc finger domain mediates binding to an E2
CC ubiquitin-conjugating enzyme. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RING-type zinc finger family. ATL subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC36179.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AC005314; AAC36179.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002685; AEC09107.1; -; Genomic_DNA.
DR EMBL; BT012632; AAT06451.1; -; mRNA.
DR PIR; D84768; D84768.
DR RefSeq; NP_181085.2; NM_129094.2.
DR AlphaFoldDB; Q6NKR1; -.
DR SMR; Q6NKR1; -.
DR PaxDb; Q6NKR1; -.
DR PRIDE; Q6NKR1; -.
DR EnsemblPlants; AT2G35420.1; AT2G35420.1; AT2G35420.
DR GeneID; 818108; -.
DR Gramene; AT2G35420.1; AT2G35420.1; AT2G35420.
DR KEGG; ath:AT2G35420; -.
DR Araport; AT2G35420; -.
DR TAIR; locus:2062502; AT2G35420.
DR eggNOG; KOG0800; Eukaryota.
DR HOGENOM; CLU_035191_3_1_1; -.
DR InParanoid; Q6NKR1; -.
DR OMA; SNCIDLW; -.
DR OrthoDB; 784082at2759; -.
DR PhylomeDB; Q6NKR1; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q6NKR1; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q6NKR1; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Membrane; Metal-binding; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix; Ubl conjugation pathway; Zinc; Zinc-finger.
FT CHAIN 1..254
FT /note="RING-H2 finger protein ATL28"
FT /id="PRO_0000055780"
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ZN_FING 103..145
FT /note="RING-type; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
SQ SEQUENCE 254 AA; 28623 MW; 03B8B8A332496358 CRC64;
MSSTTSIDSI PATAVFPSVS MPVTVVLTGV LLFVIFAGFF SLFLWQFLLN RLFTTWNLQR
TPYGDLIHVA TPPENTGLDP FIIRSFPVFH YSSATKKNHG TECAICLSEF SDEDTVRLIT
VCRHPFHSNC IDLWFELHKT CPVCRCELDP GMIGSGRLES FHNTVTITIQ DINHDEENPP
TAGSSKRLIE ASAWRFSRSH STGHFMVKTT DANVKSKRRH YQTGSCVSFD ELTRYEGAGW
QWLGDSSHIS RIEV
