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ATL38_ARATH
ID   ATL38_ARATH             Reviewed;         302 AA.
AC   O64762; Q4PSR9;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=RING-H2 finger protein ATL38;
DE            EC=2.3.2.27 {ECO:0000305};
DE   AltName: Full=RING-type E3 ubiquitin transferase ATL38 {ECO:0000305};
GN   Name=ATL38; OrderedLocusNames=At2g34990; ORFNames=F19I3.22;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA   Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   GENE FAMILY ORGANIZATION.
RX   PubMed=11983057; DOI=10.1186/gb-2002-3-4-research0016;
RA   Kosarev P., Mayer K.F.X., Hardtke C.S.;
RT   "Evaluation and classification of RING-finger domains encoded by the
RT   Arabidopsis genome.";
RL   Genome Biol. 3:RESEARCH0016.1-RESEARCH0016.12(2002).
RN   [5]
RP   NOMENCLATURE, AND GENE FAMILY ORGANIZATION.
RX   PubMed=16557337; DOI=10.1007/s00239-005-0038-y;
RA   Serrano M., Parra S., Alcaraz L.D., Guzman P.;
RT   "The ATL gene family from Arabidopsis thaliana and Oryza sativa comprises a
RT   large number of putative ubiquitin ligases of the RING-H2 type.";
RL   J. Mol. Evol. 62:434-445(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27; Evidence={ECO:0000305};
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DOMAIN: The RING-type zinc finger domain mediates binding to an E2
CC       ubiquitin-conjugating enzyme. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RING-type zinc finger family. ATL subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AC004238; AAC12838.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC09046.1; -; Genomic_DNA.
DR   EMBL; DQ056567; AAY78717.1; -; mRNA.
DR   PIR; T00480; T00480.
DR   RefSeq; NP_181044.1; NM_129051.2.
DR   AlphaFoldDB; O64762; -.
DR   SMR; O64762; -.
DR   STRING; 3702.AT2G34990.1; -.
DR   PaxDb; O64762; -.
DR   PRIDE; O64762; -.
DR   EnsemblPlants; AT2G34990.1; AT2G34990.1; AT2G34990.
DR   GeneID; 818063; -.
DR   Gramene; AT2G34990.1; AT2G34990.1; AT2G34990.
DR   KEGG; ath:AT2G34990; -.
DR   Araport; AT2G34990; -.
DR   TAIR; locus:2044742; AT2G34990.
DR   eggNOG; KOG0800; Eukaryota.
DR   HOGENOM; CLU_035191_1_0_1; -.
DR   InParanoid; O64762; -.
DR   PhylomeDB; O64762; -.
DR   UniPathway; UPA00143; -.
DR   PRO; PR:O64762; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; O64762; baseline and differential.
DR   Genevisible; O64762; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Metal-binding; Reference proteome; Transferase; Transmembrane;
KW   Transmembrane helix; Ubl conjugation pathway; Zinc; Zinc-finger.
FT   CHAIN           1..302
FT                   /note="RING-H2 finger protein ATL38"
FT                   /id="PRO_0000055779"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   ZN_FING         96..138
FT                   /note="RING-type; atypical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          279..302
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   302 AA;  34171 MW;  AE4F64FF0C252A2C CRC64;
     MVQPGTEIKA SDLTLLVITI ILFAIFIVGL ASVCFRWTSR QFYSQESINP FTDSDVESRT
     SITAVRGLDE AIINSFPTFL YSEVKERRIG IGGVECAVCI CEFEDHETLR LMPECCHVFH
     ADCVSVWLSD HSTCPLCRVD LCLQPGERSY LNPEPDLVES TNSHLFDGVT WTNRNRPSRS
     WSTRLSQCRV SQILISRSHS TGHSVVQPLD NLDRFTLRLP EEVRRQLTKK TVDNVAFSQA
     RSSRRGYRSR SAGSERSVFS YQRRMHSFSD CAWSTSCGGE AVAPSKDSRR ISVEQSQLDD
     RV
 
 
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