ATL43_ARATH
ID ATL43_ARATH Reviewed; 407 AA.
AC Q5EAE9; F4K0U7; Q9FFJ7;
DT 05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2005, sequence version 2.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=RING-H2 finger protein ATL43;
DE EC=2.3.2.27 {ECO:0000305};
DE AltName: Full=RING-type E3 ubiquitin transferase ATL43 {ECO:0000305};
DE Flags: Precursor;
GN Name=ATL43; OrderedLocusNames=At5g05810; ORFNames=MJJ3.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT features of the 1.6 Mb regions covered by twenty physically assigned P1
RT clones.";
RL DNA Res. 4:215-230(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 21-407.
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 55-407.
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY ORGANIZATION.
RX PubMed=11983057; DOI=10.1186/gb-2002-3-4-research0016;
RA Kosarev P., Mayer K.F.X., Hardtke C.S.;
RT "Evaluation and classification of RING-finger domains encoded by the
RT Arabidopsis genome.";
RL Genome Biol. 3:RESEARCH0016.1-RESEARCH0016.12(2002).
RN [6]
RP NOMENCLATURE, AND GENE FAMILY ORGANIZATION.
RX PubMed=16557337; DOI=10.1007/s00239-005-0038-y;
RA Serrano M., Parra S., Alcaraz L.D., Guzman P.;
RT "The ATL gene family from Arabidopsis thaliana and Oryza sativa comprises a
RT large number of putative ubiquitin ligases of the RING-H2 type.";
RL J. Mol. Evol. 62:434-445(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000305};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- DOMAIN: The RING-type zinc finger domain mediates binding to an E2
CC ubiquitin-conjugating enzyme. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RING-type zinc finger family. ATL subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAW81728.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AB005237; BAB09675.1; -; Genomic_DNA.
DR EMBL; CP002688; AED90928.2; -; Genomic_DNA.
DR EMBL; BT020620; AAW81728.1; ALT_INIT; mRNA.
DR EMBL; BT021932; AAX49381.1; -; mRNA.
DR RefSeq; NP_196200.3; NM_120663.3.
DR AlphaFoldDB; Q5EAE9; -.
DR SMR; Q5EAE9; -.
DR STRING; 3702.AT5G05810.1; -.
DR PaxDb; Q5EAE9; -.
DR PRIDE; Q5EAE9; -.
DR EnsemblPlants; AT5G05810.1; AT5G05810.1; AT5G05810.
DR GeneID; 830466; -.
DR Gramene; AT5G05810.1; AT5G05810.1; AT5G05810.
DR KEGG; ath:AT5G05810; -.
DR Araport; AT5G05810; -.
DR eggNOG; KOG0800; Eukaryota.
DR HOGENOM; CLU_046350_1_0_1; -.
DR InParanoid; Q5EAE9; -.
DR OMA; GCFDRPR; -.
DR OrthoDB; 1376310at2759; -.
DR PhylomeDB; Q5EAE9; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q5EAE9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q5EAE9; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Membrane; Metal-binding; Reference proteome; Signal; Transferase;
KW Transmembrane; Transmembrane helix; Ubl conjugation pathway; Zinc;
KW Zinc-finger.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..407
FT /note="RING-H2 finger protein ATL43"
FT /id="PRO_0000030715"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ZN_FING 146..188
FT /note="RING-type; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
SQ SEQUENCE 407 AA; 45269 MW; 7DEC986700D90A42 CRC64;
MSSSSLILLF STLSLFLNVS LADNHTAVVI TTSDTPPPLP PPSPPPRHNF TSSLMPGIAV
VIAVLTAFFS LTFLLLLYVK HCKRRNGSVY VNHPQRFAIT RYGGGYYNGG GVVGGRKNSG
IDRSVIESLP VFRFGALSGH KDGLECAVCL ARFEPTEVLR LLPKCKHAFH VECVDTWLDA
HSTCPLCRYR VDPEDILLIG DCNSWFELQF SKDESNSVNN NPPGLTRFIP VSRISGRHSS
AGERASRLNE IRTSSSYKSN PMSFRRSLDS SLKVNDAGEE KSESVAVNCL DRLQRKDGLL
LIPNRESFEG RFEHRIIISG GNRDDQRWSE VRPSDLLYLR SEMILSDCRK LAAAEGGRDV
INGRSVSELT GIERRRRWGG EPRQRQATAV ISRWLAWSHR ASASSIV
