ATL73_ARATH
ID ATL73_ARATH Reviewed; 176 AA.
AC Q9FLC6;
DT 05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=RING-H2 finger protein ATL73;
DE EC=2.3.2.27 {ECO:0000305};
DE AltName: Full=RING-type E3 ubiquitin transferase ATL73 {ECO:0000305};
DE Flags: Precursor;
GN Name=ATL73; OrderedLocusNames=At5g05280; ORFNames=K18I23.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT features of the regions of 1,381,565 bp covered by twenty one physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:131-145(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP GENE FAMILY ORGANIZATION.
RX PubMed=11983057; DOI=10.1186/gb-2002-3-4-research0016;
RA Kosarev P., Mayer K.F.X., Hardtke C.S.;
RT "Evaluation and classification of RING-finger domains encoded by the
RT Arabidopsis genome.";
RL Genome Biol. 3:RESEARCH0016.1-RESEARCH0016.12(2002).
RN [5]
RP NOMENCLATURE, AND GENE FAMILY ORGANIZATION.
RX PubMed=16557337; DOI=10.1007/s00239-005-0038-y;
RA Serrano M., Parra S., Alcaraz L.D., Guzman P.;
RT "The ATL gene family from Arabidopsis thaliana and Oryza sativa comprises a
RT large number of putative ubiquitin ligases of the RING-H2 type.";
RL J. Mol. Evol. 62:434-445(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000305};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- DOMAIN: The RING-type zinc finger domain mediates binding to an E2
CC ubiquitin-conjugating enzyme. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RING-type zinc finger family. ATL subfamily.
CC {ECO:0000305}.
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DR EMBL; AB010692; BAB09971.1; -; Genomic_DNA.
DR EMBL; CP002688; AED90850.1; -; Genomic_DNA.
DR EMBL; BX830198; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_196147.1; NM_120610.2.
DR AlphaFoldDB; Q9FLC6; -.
DR SMR; Q9FLC6; -.
DR STRING; 3702.AT5G05280.1; -.
DR PaxDb; Q9FLC6; -.
DR PRIDE; Q9FLC6; -.
DR EnsemblPlants; AT5G05280.1; AT5G05280.1; AT5G05280.
DR GeneID; 830410; -.
DR Gramene; AT5G05280.1; AT5G05280.1; AT5G05280.
DR KEGG; ath:AT5G05280; -.
DR Araport; AT5G05280; -.
DR TAIR; locus:2153554; AT5G05280.
DR eggNOG; KOG0800; Eukaryota.
DR HOGENOM; CLU_013137_9_3_1; -.
DR InParanoid; Q9FLC6; -.
DR OMA; RLIIRWA; -.
DR OrthoDB; 1352099at2759; -.
DR PhylomeDB; Q9FLC6; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9FLC6; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FLC6; baseline and differential.
DR Genevisible; Q9FLC6; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IDA:TAIR.
DR GO; GO:0009901; P:anther dehiscence; IMP:TAIR.
DR GO; GO:0009555; P:pollen development; IMP:TAIR.
DR GO; GO:0016567; P:protein ubiquitination; IDA:TAIR.
DR GO; GO:0080141; P:regulation of jasmonic acid biosynthetic process; IMP:TAIR.
DR GO; GO:0048443; P:stamen development; IMP:TAIR.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Membrane; Metal-binding; Reference proteome; Signal; Transferase;
KW Transmembrane; Transmembrane helix; Ubl conjugation pathway; Zinc;
KW Zinc-finger.
FT SIGNAL 1..16
FT /evidence="ECO:0000255"
FT CHAIN 17..176
FT /note="RING-H2 finger protein ATL73"
FT /id="PRO_0000030714"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ZN_FING 113..155
FT /note="RING-type; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
SQ SEQUENCE 176 AA; 19120 MW; 5E9D8A14BA0172E7 CRC64;
MARFLLATQA TPTISATDAN PRTLGDSVSN NKNIASMDTH MVIILAALLC ALICALGINS
VLRCVLRCTR RFTPNEDPVD TNANVAKGIK KRALKVIPVD SYSPELKMKA TECLICLGDF
VEGETVRVLP KCNHGFHVKC IDTWLLSHSS CPTCRQSLLE HQTPANGSRR GDDVAT
