ID   PSD_AZOVI               Reviewed;          48 AA.
AC   Q44558;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Phosphatidylserine decarboxylase proenzyme;
DE            EC=4.1.1.65;
DE   Contains:
DE     RecName: Full=Phosphatidylserine decarboxylase beta chain;
DE   Flags: Fragment;
GN   Name=psd;
OS   Azotobacter vinelandii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Azotobacter.
OX   NCBI_TaxID=354;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=OP / UW136;
RX   PubMed=8617271; DOI=10.1111/j.1432-1033.1996.00240.x;
RA   Colnaghi R., Pagani S., Kennedy C., Drummond M.;
RT   "Cloning, sequence analysis and overexpression of the rhodanese gene of
RT   Azotobacter vinelandii.";
RL   Eur. J. Biochem. 236:240-248(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-
CC         diacyl-sn-glycero-3-phosphoethanolamine + CO2; Xref=Rhea:RHEA:20828,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:57262,
CC         ChEBI:CHEBI:64612; EC=4.1.1.65;
CC   -!- COFACTOR:
CC       Name=pyruvate; Xref=ChEBI:CHEBI:15361; Evidence={ECO:0000250};
CC       Note=Binds 1 pyruvoyl group covalently per subunit. {ECO:0000250};
CC   -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC       biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step
CC       2/2.
CC   -!- SIMILARITY: Belongs to the phosphatidylserine decarboxylase family.
CC       Type 1 subfamily. {ECO:0000305}.
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DR   EMBL; L42346; AAB03238.1; -; Genomic_DNA.
DR   PIR; S62189; S62189.
DR   AlphaFoldDB; Q44558; -.
DR   SMR; Q44558; -.
DR   UniPathway; UPA00558; UER00616.
DR   GO; GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
PE   3: Inferred from homology;
KW   Decarboxylase; Lipid biosynthesis; Lipid metabolism; Lyase;
KW   Phospholipid biosynthesis; Phospholipid metabolism; Pyruvate.
FT   CHAIN           1..>48
FT                   /note="Phosphatidylserine decarboxylase beta chain"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000029618"
FT   NON_TER         48
SQ   SEQUENCE   48 AA;  5591 MW;  366CC6E30EC3F689 CRC64;
     MKDRLFLLGQ HLLPHHLLSR AAGRLAECRV PWVKNSLIKA FARHFQVD