PSF1_ASHGO
ID PSF1_ASHGO Reviewed; 203 AA.
AC Q75E92;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=DNA replication complex GINS protein PSF1;
GN Name=PSF1; OrderedLocusNames=AAR188W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. {ECO:0000250}.
CC -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GINS1/PSF1 family. {ECO:0000305}.
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DR EMBL; AE016814; AAS50555.1; -; Genomic_DNA.
DR RefSeq; NP_982731.1; NM_208084.1.
DR AlphaFoldDB; Q75E92; -.
DR SMR; Q75E92; -.
DR STRING; 33169.AAS50555; -.
DR EnsemblFungi; AAS50555; AAS50555; AGOS_AAR188W.
DR GeneID; 4618769; -.
DR KEGG; ago:AGOS_AAR188W; -.
DR eggNOG; KOG3303; Eukaryota.
DR HOGENOM; CLU_079191_0_0_1; -.
DR InParanoid; Q75E92; -.
DR OMA; NHLCMRR; -.
DR Proteomes; UP000000591; Chromosome I.
DR GO; GO:0071162; C:CMG complex; IEA:EnsemblFungi.
DR GO; GO:0000811; C:GINS complex; IBA:GO_Central.
DR GO; GO:0031298; C:replication fork protection complex; IEA:EnsemblFungi.
DR GO; GO:1902983; P:DNA strand elongation involved in mitotic DNA replication; IBA:GO_Central.
DR GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:EnsemblFungi.
DR GO; GO:0000727; P:double-strand break repair via break-induced replication; IEA:EnsemblFungi.
DR GO; GO:1902975; P:mitotic DNA replication initiation; IEA:EnsemblFungi.
DR CDD; cd11710; GINS_A_psf1; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR005339; GINS_Psf1.
DR PANTHER; PTHR12914; PTHR12914; 1.
DR Pfam; PF05916; Sld5; 1.
DR SUPFAM; SSF158573; SSF158573; 1.
PE 3: Inferred from homology;
KW DNA replication; Nucleus; Reference proteome.
FT CHAIN 1..203
FT /note="DNA replication complex GINS protein PSF1"
FT /id="PRO_0000278392"
SQ SEQUENCE 203 AA; 23184 MW; A5C9906DCC4BF4E1 CRC64;
MYGDVANKLV LEAKRTDHLA NGSATLQLPM FQDEMVRVIL KEVSQLQRNA EYLKLQEDSG
KLSKCQYFVT MLCMERNKRC LLAYQKTRSE ILDAIAWENN GLDTMDLLSN KGHDSGNLSP
YEQEYLREYS QLISDLTAGE LMDIDLAGSL TPPSDVFIDV RVLKDAGEIQ TEYGVFNLIK
DSQFFVRQAD VERLIQQGYL QKL