ID   PSF1_CAEEL              Reviewed;         201 AA.
AC   Q22019;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 2.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=Probable DNA replication complex GINS protein PSF1;
DE   AltName: Full=GINS complex subunit 1;
GN   Name=psf-1 {ECO:0000312|WormBase:R53.6};
GN   ORFNames=R53.6 {ECO:0000312|WormBase:R53.6};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       gins1, gins2, gins3 and gins4. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GINS1/PSF1 family. {ECO:0000305}.
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DR   EMBL; Z66515; CAA91348.2; -; Genomic_DNA.
DR   PIR; T24245; T24245.
DR   RefSeq; NP_496153.2; NM_063752.4.
DR   AlphaFoldDB; Q22019; -.
DR   SMR; Q22019; -.
DR   BioGRID; 52563; 35.
DR   STRING; 6239.R53.6.2; -.
DR   EPD; Q22019; -.
DR   PaxDb; Q22019; -.
DR   PeptideAtlas; Q22019; -.
DR   EnsemblMetazoa; R53.6.1; R53.6.1; WBGene00011275.
DR   GeneID; 187885; -.
DR   KEGG; cel:CELE_R53.6; -.
DR   UCSC; R53.6; c. elegans.
DR   CTD; 187885; -.
DR   WormBase; R53.6; CE35902; WBGene00011275; psf-1.
DR   eggNOG; KOG3303; Eukaryota.
DR   GeneTree; ENSGT00390000013968; -.
DR   HOGENOM; CLU_079191_1_0_1; -.
DR   InParanoid; Q22019; -.
DR   OMA; AMCHIRR; -.
DR   OrthoDB; 1249159at2759; -.
DR   PhylomeDB; Q22019; -.
DR   Reactome; R-CEL-176974; Unwinding of DNA.
DR   PRO; PR:Q22019; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00011275; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0000811; C:GINS complex; IBA:GO_Central.
DR   GO; GO:1902983; P:DNA strand elongation involved in mitotic DNA replication; IBA:GO_Central.
DR   CDD; cd11710; GINS_A_psf1; 1.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR005339; GINS_Psf1.
DR   PANTHER; PTHR12914; PTHR12914; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   SUPFAM; SSF158573; SSF158573; 1.
PE   3: Inferred from homology;
KW   DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..201
FT                   /note="Probable DNA replication complex GINS protein PSF1"
FT                   /id="PRO_0000219038"
SQ   SEQUENCE   201 AA;  22736 MW;  6306E80D7309D3AC CRC64;
     MSSGDQNRGG VADKALQLVL EMKRNPDVLP PYNTELVRQC YQKIDELFQK NAAVVEKIRA
     GLPHDSTLLQ PRLAAMCHIR RCMMAYVNER KNRIRSFRWK YGGALPASVR NALCDAEIQF
     FNEYSSTLAR FQSNLGEGGV NLLLHSAPPK SLFVQVRALE DYGEFETSDG TQVQLSKDSL
     HSLPRQDCEM LIRQGVLELV H