PSF1_CANAL
ID PSF1_CANAL Reviewed; 236 AA.
AC Q59S42; A0A1D8PQS4; Q3MPL0;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=DNA replication complex GINS protein PSF1;
GN Name=PSF1; OrderedLocusNames=CAALFM_C701300CA;
GN ORFNames=CaJ7.0144, CaO19.6910;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15937140; DOI=10.1534/genetics.104.034652;
RA Chibana H., Oka N., Nakayama H., Aoyama T., Magee B.B., Magee P.T.,
RA Mikami Y.;
RT "Sequence finishing and gene mapping for Candida albicans chromosome 7 and
RT syntenic analysis against the Saccharomyces cerevisiae genome.";
RL Genetics 170:1525-1537(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. {ECO:0000250}.
CC -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GINS1/PSF1 family. {ECO:0000305}.
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DR EMBL; AP006852; BAE44650.1; -; Genomic_DNA.
DR EMBL; CP017629; AOW30498.1; -; Genomic_DNA.
DR RefSeq; XP_712482.1; XM_707389.1.
DR AlphaFoldDB; Q59S42; -.
DR SMR; Q59S42; -.
DR STRING; 237561.Q59S42; -.
DR PRIDE; Q59S42; -.
DR GeneID; 3645894; -.
DR KEGG; cal:CAALFM_C701300CA; -.
DR CGD; CAL0000199213; PSF1.
DR VEuPathDB; FungiDB:C7_01300C_A; -.
DR eggNOG; KOG3303; Eukaryota.
DR HOGENOM; CLU_079191_0_0_1; -.
DR InParanoid; Q59S42; -.
DR OMA; NHLCMRR; -.
DR OrthoDB; 1249159at2759; -.
DR Proteomes; UP000000559; Chromosome 7.
DR GO; GO:0000811; C:GINS complex; IBA:GO_Central.
DR GO; GO:1902983; P:DNA strand elongation involved in mitotic DNA replication; IBA:GO_Central.
DR GO; GO:1902975; P:mitotic DNA replication initiation; IEA:EnsemblFungi.
DR CDD; cd11710; GINS_A_psf1; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR005339; GINS_Psf1.
DR PANTHER; PTHR12914; PTHR12914; 1.
DR Pfam; PF05916; Sld5; 1.
DR SUPFAM; SSF158573; SSF158573; 1.
PE 3: Inferred from homology;
KW DNA replication; Nucleus; Reference proteome.
FT CHAIN 1..236
FT /note="DNA replication complex GINS protein PSF1"
FT /id="PRO_0000278395"
FT REGION 109..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 236 AA; 27078 MW; 21F7C0198DC63903 CRC64;
MFGDTANKLI LDAKRSSNLS AIPIYQSDLV KSIVRETNDL NKDAEYLVEE QEQLQETQDQ
ENSKINQCQL FVTHLSMRRN KRCLLAYEKS RADKITEFCW LNIDPIETST SSSTTSTNTN
SNVNQSSSNN AVNPLTKNLS NYTTSLDMNN LNHHEQDFFK QYQDLIMEFK SSFEDIDLSG
DLNPPTNIFI DVRVLKDGGE VTTEYGSFNL IKDSQFFVRK SDVERLIQQG YLEEII