ID   PSF1_CANGA              Reviewed;         222 AA.
AC   Q6FVY5;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=DNA replication complex GINS protein PSF1;
GN   Name=PSF1; OrderedLocusNames=CAGL0D04466g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GINS1/PSF1 family. {ECO:0000305}.
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DR   EMBL; CR380950; CAG58520.1; -; Genomic_DNA.
DR   RefSeq; XP_445609.1; XM_445609.1.
DR   AlphaFoldDB; Q6FVY5; -.
DR   SMR; Q6FVY5; -.
DR   STRING; 5478.XP_445609.1; -.
DR   EnsemblFungi; CAG58520; CAG58520; CAGL0D04466g.
DR   GeneID; 2887234; -.
DR   KEGG; cgr:CAGL0D04466g; -.
DR   CGD; CAL0128289; CAGL0D04466g.
DR   VEuPathDB; FungiDB:CAGL0D04466g; -.
DR   eggNOG; KOG3303; Eukaryota.
DR   HOGENOM; CLU_079191_0_0_1; -.
DR   InParanoid; Q6FVY5; -.
DR   OMA; EAHRSQQ; -.
DR   Proteomes; UP000002428; Chromosome D.
DR   GO; GO:0071162; C:CMG complex; IEA:EnsemblFungi.
DR   GO; GO:0000811; C:GINS complex; IEA:EnsemblFungi.
DR   GO; GO:0031298; C:replication fork protection complex; IEA:EnsemblFungi.
DR   GO; GO:1902983; P:DNA strand elongation involved in mitotic DNA replication; IEA:EnsemblFungi.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:EnsemblFungi.
DR   GO; GO:0000727; P:double-strand break repair via break-induced replication; IEA:EnsemblFungi.
DR   GO; GO:1902975; P:mitotic DNA replication initiation; IEA:EnsemblFungi.
DR   CDD; cd11710; GINS_A_psf1; 1.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR005339; GINS_Psf1.
DR   PANTHER; PTHR12914; PTHR12914; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   SUPFAM; SSF158573; SSF158573; 1.
PE   3: Inferred from homology;
KW   DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..222
FT                   /note="DNA replication complex GINS protein PSF1"
FT                   /id="PRO_0000278396"
SQ   SEQUENCE   222 AA;  25662 MW;  AD1ED923EC050873 CRC64;
     MYGDLANKLI LEAKRTQQLN QRRVNEDLQS GGGVNLLSRL PIYHDELVRN ILNEVDQLRR
     NAEFLRNNGN AEEFAHLDEK IVKCQYFVTL LCMERNKRCL LAYQKLRTDI LDNIAWCNNG
     TGIELYSGSN EDETNSLSHY EQEYLKEYGE LITELKSESM ADIDLSGSLE PPSDVFIDVR
     VLKDAGEIQT EYGVFNLIKD SQFFVRQSDV ERLIQQGYLQ KI