ID   PSF1_SCHPO              Reviewed;         202 AA.
AC   Q9P7X6;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 124.
DE   RecName: Full=DNA replication complex GINS protein psf1;
GN   Name=psf1; ORFNames=SPBP23A10.09;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       sld5, psf1, psf2 and psf3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the GINS1/PSF1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU329671; CAB66437.1; -; Genomic_DNA.
DR   PIR; T50396; T50396.
DR   RefSeq; NP_595821.1; NM_001021725.2.
DR   AlphaFoldDB; Q9P7X6; -.
DR   SMR; Q9P7X6; -.
DR   BioGRID; 277836; 9.
DR   IntAct; Q9P7X6; 1.
DR   MINT; Q9P7X6; -.
DR   STRING; 4896.SPBP23A10.09.1; -.
DR   MaxQB; Q9P7X6; -.
DR   PaxDb; Q9P7X6; -.
DR   EnsemblFungi; SPBP23A10.09.1; SPBP23A10.09.1:pep; SPBP23A10.09.
DR   GeneID; 2541324; -.
DR   KEGG; spo:SPBP23A10.09; -.
DR   PomBase; SPBP23A10.09; psf1.
DR   VEuPathDB; FungiDB:SPBP23A10.09; -.
DR   eggNOG; KOG3303; Eukaryota.
DR   HOGENOM; CLU_079191_0_0_1; -.
DR   InParanoid; Q9P7X6; -.
DR   OMA; AMCHIRR; -.
DR   PhylomeDB; Q9P7X6; -.
DR   Reactome; R-SPO-176974; Unwinding of DNA.
DR   PRO; PR:Q9P7X6; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0000811; C:GINS complex; ISS:PomBase.
DR   GO; GO:0043596; C:nuclear replication fork; IC:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:1902983; P:DNA strand elongation involved in mitotic DNA replication; IMP:PomBase.
DR   GO; GO:1902975; P:mitotic DNA replication initiation; IMP:PomBase.
DR   CDD; cd11710; GINS_A_psf1; 1.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR005339; GINS_Psf1.
DR   PANTHER; PTHR12914; PTHR12914; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   SUPFAM; SSF158573; SSF158573; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..202
FT                   /note="DNA replication complex GINS protein psf1"
FT                   /id="PRO_0000219039"
SQ   SEQUENCE   202 AA;  23075 MW;  B1B75F0B23555105 CRC64;
     MENGLGNRSN KLIRDSKRTQ YLDYLPPYQA DTVNDVVNEI RAADRESLGI LQNVTHEASQ
     PFQPQDHPSE AAALLMFHSS SIYNKRCLMA YHNLRLQRLR QYCWSGGKRM ESCLDTSLST
     YERDYLTRYS ELLAAYKGAW SELDLTGSLV PPKNLFIDVR VLKDVGDIET EYGTINLTKN
     SQLHVRATDV ERLIAQGFLA KL