PSF1_YARLI
ID PSF1_YARLI Reviewed; 186 AA.
AC Q6CHE4;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=DNA replication complex GINS protein PSF1;
GN Name=PSF1; OrderedLocusNames=YALI0A09746g;
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. {ECO:0000250}.
CC -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GINS1/PSF1 family. {ECO:0000305}.
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DR EMBL; CR382127; CAG83844.1; -; Genomic_DNA.
DR RefSeq; XP_499917.1; XM_499917.1.
DR AlphaFoldDB; Q6CHE4; -.
DR SMR; Q6CHE4; -.
DR STRING; 4952.CAG83844; -.
DR EnsemblFungi; CAG83844; CAG83844; YALI0_A09746g.
DR GeneID; 2905800; -.
DR KEGG; yli:YALI0A09746g; -.
DR VEuPathDB; FungiDB:YALI0_A09746g; -.
DR HOGENOM; CLU_079191_0_0_1; -.
DR InParanoid; Q6CHE4; -.
DR OMA; NHLCMRR; -.
DR Proteomes; UP000001300; Chromosome A.
DR GO; GO:0000811; C:GINS complex; IBA:GO_Central.
DR GO; GO:1902983; P:DNA strand elongation involved in mitotic DNA replication; IBA:GO_Central.
DR GO; GO:1902975; P:mitotic DNA replication initiation; IEA:EnsemblFungi.
DR CDD; cd11710; GINS_A_psf1; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR005339; GINS_Psf1.
DR PANTHER; PTHR12914; PTHR12914; 1.
DR Pfam; PF05916; Sld5; 1.
DR SUPFAM; SSF158573; SSF158573; 1.
PE 3: Inferred from homology;
KW DNA replication; Nucleus; Reference proteome.
FT CHAIN 1..186
FT /note="DNA replication complex GINS protein PSF1"
FT /id="PRO_0000278406"
SQ SEQUENCE 186 AA; 21477 MW; E91BB73E3EB1B362 CRC64;
MLGDTALKLV HDSRRTAALD LLPAYQEELV RGVCREIRQL DASINKTQDE PGYDPQDRVA
HCNLLVQHLA MRRDKRCLLA YQFTRARRMN EAAWKQTEEP NLNGNEQEYM KAYEDLIVDI
KGPYTDIDLT GSLEPPNDVF IDVRVLQSVG EVQTEYGVFN LEKDSQFFVR RSDVQTLLLQ
GYLKEI