PSF2_ARATH
ID PSF2_ARATH Reviewed; 210 AA.
AC Q9C7A8; Q5EAG9; Q9LHF6;
DT 24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 24-OCT-2003, sequence version 2.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=DNA replication complex GINS protein PSF2;
GN Name=GINS2; OrderedLocusNames=At3g12530; ORFNames=MQC3.35, T2E22.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. {ECO:0000250}.
CC -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC GINS1, GINS2, GINS3 and GINS4. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9C7A8-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the GINS2/PSF2 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG51015.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=BAB03160.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP002047; BAB03160.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP002055; BAB03160.1; JOINED; Genomic_DNA.
DR EMBL; AC069474; AAG51015.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002686; AEE75207.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM64291.1; -; Genomic_DNA.
DR EMBL; BT010931; AAR24709.1; -; mRNA.
DR EMBL; BT020600; AAW80873.1; -; mRNA.
DR RefSeq; NP_001030680.1; NM_001035603.1.
DR RefSeq; NP_001319531.1; NM_001337995.1. [Q9C7A8-1]
DR RefSeq; NP_187859.2; NM_112088.3. [Q9C7A8-1]
DR AlphaFoldDB; Q9C7A8; -.
DR SMR; Q9C7A8; -.
DR BioGRID; 5766; 1.
DR IntAct; Q9C7A8; 1.
DR STRING; 3702.AT3G12530.1; -.
DR PaxDb; Q9C7A8; -.
DR PRIDE; Q9C7A8; -.
DR DNASU; 820432; -.
DR EnsemblPlants; AT3G12530.1; AT3G12530.1; AT3G12530. [Q9C7A8-1]
DR EnsemblPlants; AT3G12530.3; AT3G12530.3; AT3G12530. [Q9C7A8-1]
DR GeneID; 820432; -.
DR Gramene; AT3G12530.1; AT3G12530.1; AT3G12530. [Q9C7A8-1]
DR Gramene; AT3G12530.3; AT3G12530.3; AT3G12530. [Q9C7A8-1]
DR KEGG; ath:AT3G12530; -.
DR Araport; AT3G12530; -.
DR TAIR; locus:2101247; AT3G12530.
DR eggNOG; KOG4071; Eukaryota.
DR HOGENOM; CLU_078274_2_2_1; -.
DR InParanoid; Q9C7A8; -.
DR OMA; PYHWLEL; -.
DR PhylomeDB; Q9C7A8; -.
DR PRO; PR:Q9C7A8; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9C7A8; baseline and differential.
DR Genevisible; Q9C7A8; AT.
DR GO; GO:0000811; C:GINS complex; IBA:GO_Central.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR GO; GO:0000727; P:double-strand break repair via break-induced replication; IBA:GO_Central.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR007257; GINS_Psf2.
DR PANTHER; PTHR12772; PTHR12772; 1.
DR Pfam; PF05916; Sld5; 1.
DR PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR SUPFAM; SSF158573; SSF158573; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA replication; Nucleus; Reference proteome.
FT CHAIN 1..210
FT /note="DNA replication complex GINS protein PSF2"
FT /id="PRO_0000194819"
FT REGION 182..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 210 AA; 24291 MW; EA04994417110588 CRC64;
MAGQTDPHIS LFSPQEVEFM AEDELVEIVP NMNMEQLNFI SGDFGRFIPQ IPTKVPLWLA
VALKRRGKCT FRPPGWMSVD NLTQILEAER ESQSTFQALP FSYVEIARLL FDHARDDIPD
MYMVRSLVED IRDVRLHKLE TNLGSFQGTS AVKISNVSAM EVNIVRPFVI RALEAFYKHD
KPEADVDRDT RSSRQQRETN NEPRRPLRQR
