ID   PSF2_BRUMA              Reviewed;         190 AA.
AC   Q8IHI1;
DT   24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Probable DNA replication complex GINS protein PSF2;
DE   AltName: Full=GINS complex subunit 2;
GN   ORFNames=BMBAC01P19.06;
OS   Brugia malayi (Filarial nematode worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX   NCBI_TaxID=6279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Gulliano D.B., Hall N., Jones S.J.M., Clark L.N., Corton C.H.,
RA   Barrell B.G., Blaxter M.L.;
RT   "Conservation of long-range and micro-synteny between the genomes of two
RT   distantly related nematodes.";
RL   Genome Biol. 3:RESEARCH0057.1-RESEARCH0057.14(2002).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       gins1, gins2, gins3 and gins4. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GINS2/PSF2 family. {ECO:0000305}.
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DR   EMBL; AL606837; CAC70161.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8IHI1; -.
DR   SMR; Q8IHI1; -.
DR   STRING; 6279.Q8IHI1; -.
DR   WormBase; Bm3720; BM03790; WBGene00223981; Bma-psf-2.
DR   Proteomes; UP000006672; Unassembled WGS sequence.
DR   GO; GO:0000228; C:nuclear chromosome; IEA:UniProt.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR007257; GINS_Psf2.
DR   PANTHER; PTHR12772; PTHR12772; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR   SUPFAM; SSF158573; SSF158573; 1.
PE   3: Inferred from homology;
KW   DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..190
FT                   /note="Probable DNA replication complex GINS protein PSF2"
FT                   /id="PRO_0000194817"
SQ   SEQUENCE   190 AA;  21893 MW;  DFB28FC76AF14566 CRC64;
     MTPEQCEFIA GNEWIQINPQ FNLDELHLIC GDIGPFEAGM PIWVPLWIAV TLRKRRKCTI
     IPPQWLCVEE LKKLVIAESG TNAFGQVPRF YLEIAHMFVQ YAKEDLPDSD MIRVYVQDLW
     DKRSAKLNNS STKFLGQVES CHARMDNITL MEVAYIKRSL ITASREIEAL NKSFHELSSQ
     NSSDQRYVIA