ID   PSF2_CAEEL              Reviewed;         180 AA.
AC   O62193;
DT   24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Probable DNA replication complex GINS protein PSF2;
DE   AltName: Full=GINS complex subunit 2;
GN   Name=psf-2; ORFNames=F31C3.5;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       gins1, gins2, gins3 and gins4. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GINS2/PSF2 family. {ECO:0000305}.
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DR   EMBL; Z92784; CAB07195.1; -; Genomic_DNA.
DR   PIR; T21590; T21590.
DR   RefSeq; NP_493627.1; NM_061226.1.
DR   AlphaFoldDB; O62193; -.
DR   SMR; O62193; -.
DR   BioGRID; 49923; 3.
DR   IntAct; O62193; 1.
DR   STRING; 6239.F31C3.5; -.
DR   EPD; O62193; -.
DR   PaxDb; O62193; -.
DR   PeptideAtlas; O62193; -.
DR   EnsemblMetazoa; F31C3.5.1; F31C3.5.1; WBGene00009287.
DR   GeneID; 185146; -.
DR   KEGG; cel:CELE_F31C3.5; -.
DR   UCSC; F31C3.5; c. elegans.
DR   CTD; 185146; -.
DR   WormBase; F31C3.5; CE17734; WBGene00009287; psf-2.
DR   eggNOG; KOG4071; Eukaryota.
DR   GeneTree; ENSGT00390000007838; -.
DR   HOGENOM; CLU_078274_2_0_1; -.
DR   InParanoid; O62193; -.
DR   OMA; PYHWLEL; -.
DR   OrthoDB; 1382842at2759; -.
DR   PhylomeDB; O62193; -.
DR   Reactome; R-CEL-176974; Unwinding of DNA.
DR   PRO; PR:O62193; -.
DR   Proteomes; UP000001940; Chromosome I.
DR   Bgee; WBGene00009287; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0000811; C:GINS complex; IBA:GO_Central.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0000727; P:double-strand break repair via break-induced replication; IBA:GO_Central.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR007257; GINS_Psf2.
DR   PANTHER; PTHR12772; PTHR12772; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR   SUPFAM; SSF158573; SSF158573; 1.
PE   3: Inferred from homology;
KW   DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..180
FT                   /note="Probable DNA replication complex GINS protein PSF2"
FT                   /id="PRO_0000194818"
SQ   SEQUENCE   180 AA;  20321 MW;  B5D0600838B67E35 CRC64;
     MNAERCEFIA GNSLIEVIPS ISDDRPIHLI SGDIGPFEAG VPCRIPVWTA ILMKRKHNCK
     VVAPQWMDVD ELKKILTSET ESQGLAKLPD HFFEISHMLV RDAREDIFEV EAVKSLVQDI
     YDRRDAKLRS SAIEFLRQNQ TCHAQLDNVQ LIEASSARAT LEACRQMGAV VRNKHESTPL