ID   PSF2_CANAL              Reviewed;         203 AA.
AC   Q59MA3; A0A1D8PDF3;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2017, sequence version 2.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=DNA replication complex GINS protein PSF2;
GN   Name=PSF2; OrderedLocusNames=CAALFM_C105030CA;
GN   ORFNames=CaO19.57, CaO19.7718;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. Has a role in chromosome segregation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GINS2/PSF2 family. {ECO:0000305}.
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DR   EMBL; CP017623; AOW26175.1; -; Genomic_DNA.
DR   RefSeq; XP_019330647.1; XM_019475102.1.
DR   AlphaFoldDB; Q59MA3; -.
DR   SMR; Q59MA3; -.
DR   STRING; 237561.Q59MA3; -.
DR   GeneID; 3647534; -.
DR   KEGG; cal:CAALFM_C105030CA; -.
DR   CGD; CAL0000196709; PSF2.
DR   VEuPathDB; FungiDB:C1_05030C_A; -.
DR   eggNOG; KOG4071; Eukaryota.
DR   HOGENOM; CLU_078274_1_1_1; -.
DR   InParanoid; Q59MA3; -.
DR   OrthoDB; 1382842at2759; -.
DR   PRO; PR:Q59MA3; -.
DR   Proteomes; UP000000559; Chromosome 1.
DR   GO; GO:0000785; C:chromatin; IEA:EnsemblFungi.
DR   GO; GO:0071162; C:CMG complex; IEA:EnsemblFungi.
DR   GO; GO:0000811; C:GINS complex; IBA:GO_Central.
DR   GO; GO:0031298; C:replication fork protection complex; IEA:EnsemblFungi.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:EnsemblFungi.
DR   GO; GO:0000727; P:double-strand break repair via break-induced replication; IBA:GO_Central.
DR   GO; GO:1902969; P:mitotic DNA replication; IEA:EnsemblFungi.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR007257; GINS_Psf2.
DR   PANTHER; PTHR12772; PTHR12772; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR   SUPFAM; SSF158573; SSF158573; 1.
PE   3: Inferred from homology;
KW   Chromosome partition; DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..203
FT                   /note="DNA replication complex GINS protein PSF2"
FT                   /id="PRO_0000255421"
SQ   SEQUENCE   203 AA;  23453 MW;  64566D04BFF1AC4F CRC64;
     MVLPKNLQGN LMPSEITFLA ENELITILPR YSIKKIDLIG TSIPNLRAMR RELVPLWVAL
     ILKSQDKCSI VPPKWLTVAY LKERYEDEIR KPLQFSDLPW NWLELSKILL EKAPDDLSDP
     VDQLRSVIQD LRETRLVKSK KGLKELNESN IQLNGLSLLE INELRPFVIP VMNKLRQLYD
     TTQSNTINAD DQDMEDASDD EDV