ID   PSF2_CANGA              Reviewed;         215 AA.
AC   Q6FS76;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=DNA replication complex GINS protein PSF2;
GN   Name=PSF2; OrderedLocusNames=CAGL0H02849g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. Has a role in chromosome segregation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GINS2/PSF2 family. {ECO:0000305}.
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DR   EMBL; CR380954; CAG59851.1; -; Genomic_DNA.
DR   RefSeq; XP_446918.1; XM_446918.1.
DR   AlphaFoldDB; Q6FS76; -.
DR   SMR; Q6FS76; -.
DR   STRING; 5478.XP_446918.1; -.
DR   EnsemblFungi; CAG59851; CAG59851; CAGL0H02849g.
DR   GeneID; 2888574; -.
DR   KEGG; cgr:CAGL0H02849g; -.
DR   CGD; CAL0131642; CAGL0H02849g.
DR   VEuPathDB; FungiDB:CAGL0H02849g; -.
DR   eggNOG; KOG4071; Eukaryota.
DR   HOGENOM; CLU_078274_1_1_1; -.
DR   InParanoid; Q6FS76; -.
DR   OMA; PYHWLEL; -.
DR   Proteomes; UP000002428; Chromosome H.
DR   GO; GO:0000785; C:chromatin; IEA:EnsemblFungi.
DR   GO; GO:0071162; C:CMG complex; IEA:EnsemblFungi.
DR   GO; GO:0000811; C:GINS complex; IEA:EnsemblFungi.
DR   GO; GO:0031298; C:replication fork protection complex; IEA:EnsemblFungi.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:EnsemblFungi.
DR   GO; GO:0000727; P:double-strand break repair via break-induced replication; IEA:EnsemblFungi.
DR   GO; GO:1902969; P:mitotic DNA replication; IEA:EnsemblFungi.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR007257; GINS_Psf2.
DR   PANTHER; PTHR12772; PTHR12772; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR   SUPFAM; SSF158573; SSF158573; 1.
PE   3: Inferred from homology;
KW   Chromosome partition; DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..215
FT                   /note="DNA replication complex GINS protein PSF2"
FT                   /id="PRO_0000255422"
SQ   SEQUENCE   215 AA;  24961 MW;  AFBB6EDA6F50D893 CRC64;
     MALPAHLQET FSPEEVQFLV EEETVKIFPR ITTRQKRRDK NRGAYGDVDT KWSMLTTEND
     NLNNMVAMRS TEVKLWIALL LKQQNKCSIV APSWLTLREL NRKIQQETNN SDRFCDLPWN
     WLVIANVLFA KAADDFHDPV HELRSKVQDL REIRQTKVLK GLKQLNASHL QLDNLSLLEI
     NELRPFIVRT MDKLREIHDS ANTDGGVVDG DEEEI