PSF2_DEBHA
ID PSF2_DEBHA Reviewed; 206 AA.
AC Q6BZ44;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 2.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=DNA replication complex GINS protein PSF2;
GN Name=PSF2; OrderedLocusNames=DEHA2A04686g;
OS Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX NCBI_TaxID=284592;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. Has a role in chromosome segregation (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GINS2/PSF2 family. {ECO:0000305}.
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DR EMBL; CR382133; CAG84480.2; -; Genomic_DNA.
DR RefSeq; XP_456525.2; XM_456525.2.
DR AlphaFoldDB; Q6BZ44; -.
DR SMR; Q6BZ44; -.
DR STRING; 4959.XP_456525.2; -.
DR PRIDE; Q6BZ44; -.
DR EnsemblFungi; CAG84480; CAG84480; DEHA2A04686g.
DR GeneID; 2899812; -.
DR KEGG; dha:DEHA2A04686g; -.
DR VEuPathDB; FungiDB:DEHA2A04686g; -.
DR eggNOG; KOG4071; Eukaryota.
DR HOGENOM; CLU_078274_1_1_1; -.
DR InParanoid; Q6BZ44; -.
DR OMA; MENTQYL; -.
DR OrthoDB; 1382842at2759; -.
DR Proteomes; UP000000599; Chromosome A.
DR GO; GO:0000228; C:nuclear chromosome; IEA:UniProt.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR007257; GINS_Psf2.
DR PANTHER; PTHR12772; PTHR12772; 1.
DR Pfam; PF05916; Sld5; 1.
DR PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR SUPFAM; SSF158573; SSF158573; 1.
PE 3: Inferred from homology;
KW Chromosome partition; DNA replication; Nucleus; Reference proteome.
FT CHAIN 1..206
FT /note="DNA replication complex GINS protein PSF2"
FT /id="PRO_0000255424"
FT REGION 182..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..206
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 206 AA; 24025 MW; E9BD4656A38E600A CRC64;
MVLPAHLQNS LMPSEVSFLA ENEYITILPR YSMKKLELIG TKVPTLRGMR REKIPIWIAV
ILKSQDKCNI VPPEWLNLIY LKEKYEEELK QPHKFSVLPW NWLEISKILL NKAADDLSDP
THQLRSIIQD LREIRLVKSR KGLKELNESN IQLDGLSLLE INELRPFVLT VMNKLRQLHE
SVNTKTDRGT GNDQDDDMYH DVSDNE
