PSF2_ENCCU
ID PSF2_ENCCU Reviewed; 175 AA.
AC Q8SV74;
DT 24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Probable DNA replication complex GINS protein PSF2;
GN OrderedLocusNames=ECU06_1410;
OS Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC Encephalitozoon.
OX NCBI_TaxID=284813;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GB-M1;
RX PubMed=11719806; DOI=10.1038/35106579;
RA Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA Vivares C.P.;
RT "Genome sequence and gene compaction of the eukaryote parasite
RT Encephalitozoon cuniculi.";
RL Nature 414:450-453(2001).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. {ECO:0000250}.
CC -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GINS2/PSF2 family. {ECO:0000305}.
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DR EMBL; AL590446; CAD25501.1; -; Genomic_DNA.
DR RefSeq; NP_585897.1; NM_001041519.1.
DR AlphaFoldDB; Q8SV74; -.
DR SMR; Q8SV74; -.
DR GeneID; 859324; -.
DR KEGG; ecu:ECU06_1410; -.
DR VEuPathDB; MicrosporidiaDB:ECU06_1410; -.
DR HOGENOM; CLU_078274_3_1_1; -.
DR InParanoid; Q8SV74; -.
DR OMA; PYHWLEL; -.
DR OrthoDB; 1382842at2759; -.
DR Proteomes; UP000000819; Chromosome VI.
DR GO; GO:0000228; C:nuclear chromosome; IEA:UniProt.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR007257; GINS_Psf2.
DR PANTHER; PTHR12772; PTHR12772; 1.
DR Pfam; PF05916; Sld5; 1.
DR PIRSF; PIRSF028998; GINS_Psf2_subgr; 1.
DR SUPFAM; SSF158573; SSF158573; 1.
PE 3: Inferred from homology;
KW DNA replication; Nucleus; Reference proteome.
FT CHAIN 1..175
FT /note="Probable DNA replication complex GINS protein PSF2"
FT /id="PRO_0000194820"
SQ SEQUENCE 175 AA; 20163 MW; 52DAE64E0B2D6DD2 CRC64;
MAISPEEILH IAYEELVEIE PMTSIPELRL LERTYPPLMP LDIARIPLYA ALLLKKSNMC
KIRLPSYLQL ESLKMSMDVE IEKADEYSCI HPYFFPLATE LLENCYNVES IEESKMIVEK
IKEIRLAKTL KGIKCLDGKA LNMNNITLFE FNEIKELILG SAEVGRRIED LAKDQ