ID   PSF3_ASHGO              Reviewed;         185 AA.
AC   Q74Z08;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=DNA replication complex GINS protein PSF3;
GN   Name=PSF3; OrderedLocusNames=AGR399C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GINS3/PSF3 family. {ECO:0000305}.
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DR   EMBL; AE016820; AAS54889.1; -; Genomic_DNA.
DR   RefSeq; NP_987065.1; NM_212127.2.
DR   AlphaFoldDB; Q74Z08; -.
DR   SMR; Q74Z08; -.
DR   STRING; 33169.AAS54889; -.
DR   EnsemblFungi; AAS54889; AAS54889; AGOS_AGR399C.
DR   GeneID; 4623369; -.
DR   KEGG; ago:AGOS_AGR399C; -.
DR   eggNOG; KOG1106; Eukaryota.
DR   HOGENOM; CLU_081646_0_1_1; -.
DR   InParanoid; Q74Z08; -.
DR   OMA; IYKEGWR; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0071162; C:CMG complex; IEA:EnsemblFungi.
DR   GO; GO:0000811; C:GINS complex; IBA:GO_Central.
DR   GO; GO:0031298; C:replication fork protection complex; IEA:EnsemblFungi.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:EnsemblFungi.
DR   GO; GO:0000727; P:double-strand break repair via break-induced replication; IEA:EnsemblFungi.
DR   GO; GO:1902975; P:mitotic DNA replication initiation; IBA:GO_Central.
DR   Gene3D; 1.20.58.2050; -; 1.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR010492; GINS_Psf3.
DR   InterPro; IPR038437; GINS_Psf3_sf.
DR   PANTHER; PTHR22768; PTHR22768; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   SUPFAM; SSF158573; SSF158573; 1.
PE   3: Inferred from homology;
KW   DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..185
FT                   /note="DNA replication complex GINS protein PSF3"
FT                   /id="PRO_0000278413"
SQ   SEQUENCE   185 AA;  20342 MW;  26DCD74D77025F62 CRC64;
     MGYYDLDDIL ADSSKFACRF NYELPGLGYL EGNPGKPVGK HSKVELPLWL ASVLATVTGE
     QEHVDEEALP FVEFLPPEMF SARVVNAIKA DAPTLDVHSI NGHFYALGTR WAALFSDAGL
     AGMLAGMVLE RALEVQRHAA SAAVEATAPT DATARMLQTL DEWERQLYRR AHAASRDAKL
     WAARR