PSF3_ASPFU
ID PSF3_ASPFU Reviewed; 178 AA.
AC Q4WQ54;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 29-MAY-2007, sequence version 2.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=DNA replication complex GINS protein psf3;
GN Name=psf3; ORFNames=AFUA_4G11620;
OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS A1100) (Aspergillus fumigatus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA Barrell B.G., Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. {ECO:0000250}.
CC -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC sld5, psf1, psf2 and psf3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GINS3/PSF3 family. {ECO:0000305}.
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DR EMBL; AAHF01000005; EAL89630.2; -; Genomic_DNA.
DR RefSeq; XP_751668.2; XM_746575.2.
DR AlphaFoldDB; Q4WQ54; -.
DR SMR; Q4WQ54; -.
DR STRING; 746128.CADAFUBP00006684; -.
DR EnsemblFungi; EAL89630; EAL89630; AFUA_4G11620.
DR GeneID; 3509726; -.
DR KEGG; afm:AFUA_4G11620; -.
DR VEuPathDB; FungiDB:Afu4g11620; -.
DR eggNOG; KOG1106; Eukaryota.
DR HOGENOM; CLU_081646_0_1_1; -.
DR InParanoid; Q4WQ54; -.
DR OMA; IYKEGWR; -.
DR OrthoDB; 1291729at2759; -.
DR Proteomes; UP000002530; Chromosome 4.
DR GO; GO:0000785; C:chromatin; IEA:EnsemblFungi.
DR GO; GO:0071162; C:CMG complex; IEA:EnsemblFungi.
DR GO; GO:0000811; C:GINS complex; IBA:GO_Central.
DR GO; GO:0031298; C:replication fork protection complex; IEA:EnsemblFungi.
DR GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:EnsemblFungi.
DR GO; GO:0000727; P:double-strand break repair via break-induced replication; IEA:EnsemblFungi.
DR GO; GO:1902975; P:mitotic DNA replication initiation; IBA:GO_Central.
DR Gene3D; 1.20.58.2050; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR010492; GINS_Psf3.
DR InterPro; IPR038437; GINS_Psf3_sf.
DR PANTHER; PTHR22768; PTHR22768; 1.
DR Pfam; PF05916; Sld5; 1.
DR SUPFAM; SSF158573; SSF158573; 1.
PE 3: Inferred from homology;
KW DNA replication; Nucleus; Reference proteome.
FT CHAIN 1..178
FT /note="DNA replication complex GINS protein psf3"
FT /id="PRO_0000278414"
SQ SEQUENCE 178 AA; 19744 MW; 5E26613E3A1D4F0C CRC64;
MSYYDVDSIL TDSQKLPCTF ELEVPGLGIL EGNPGEDIKA GTRIDLPLWL GVMLSIGARL
GTSRLVTLDL PSALSDRVVN ALKADPRTVD LRSLAPHFYS LSERVLDLFE EEEMVDVLIN
TFKKRAAEIA DHAHNPKGAL GEGADFLRGL DETERQLFRV AHDSARETRI WAGEAKKR