PSF3_CANAL
ID PSF3_CANAL Reviewed; 177 AA.
AC Q5AFK3; A0A1D8PQM6; Q3MPS7;
DT 20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=DNA replication complex GINS protein PSF3;
GN Name=PSF3; OrderedLocusNames=CAALFM_C700530CA;
GN ORFNames=CaJ7.0068, CaO19.7065;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15937140; DOI=10.1534/genetics.104.034652;
RA Chibana H., Oka N., Nakayama H., Aoyama T., Magee B.B., Magee P.T.,
RA Mikami Y.;
RT "Sequence finishing and gene mapping for Candida albicans chromosome 7 and
RT syntenic analysis against the Saccharomyces cerevisiae genome.";
RL Genetics 170:1525-1537(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC DNA replication. {ECO:0000250}.
CC -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the GINS3/PSF3 family. {ECO:0000305}.
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DR EMBL; AP006852; BAE44583.1; -; Genomic_DNA.
DR EMBL; CP017629; AOW30432.1; -; Genomic_DNA.
DR RefSeq; XP_720357.1; XM_715264.1.
DR AlphaFoldDB; Q5AFK3; -.
DR SMR; Q5AFK3; -.
DR STRING; 237561.Q5AFK3; -.
DR GeneID; 3637999; -.
DR KEGG; cal:CAALFM_C700530CA; -.
DR CGD; CAL0000201451; PSF3.
DR VEuPathDB; FungiDB:C7_00530C_A; -.
DR HOGENOM; CLU_081646_0_1_1; -.
DR InParanoid; Q5AFK3; -.
DR OMA; KFPCRFN; -.
DR OrthoDB; 1291729at2759; -.
DR Proteomes; UP000000559; Chromosome 7.
DR GO; GO:0000811; C:GINS complex; IBA:GO_Central.
DR GO; GO:1902975; P:mitotic DNA replication initiation; IBA:GO_Central.
DR Gene3D; 1.20.58.2050; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR010492; GINS_Psf3.
DR InterPro; IPR038437; GINS_Psf3_sf.
DR PANTHER; PTHR22768; PTHR22768; 1.
DR Pfam; PF05916; Sld5; 1.
DR SUPFAM; SSF158573; SSF158573; 1.
PE 3: Inferred from homology;
KW DNA replication; Nucleus; Reference proteome.
FT CHAIN 1..177
FT /note="DNA replication complex GINS protein PSF3"
FT /id="PRO_0000278416"
SQ SEQUENCE 177 AA; 20246 MW; EE2C13FF229F2BCA CRC64;
MTTDYYDLDD ILADSEKLTC KFNITVPGLG YLEGNPGKPI HEDTKLELPH WLSGILATVA
IDEDSNINFL DLADPDIIKE KVINAIKTDP LAVDLHKLTP YYYSLILKWG NLYTDKTLIA
NVMNCLKARS LEIYNFSNNA NKTLNNEFLY TLDEFERALF KSTSDSNKSM RKWLKTK