ID   PSF3_CANGA              Reviewed;         249 AA.
AC   Q6FW66;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=DNA replication complex GINS protein PSF3;
GN   Name=PSF3; OrderedLocusNames=CAGL0D02596g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GINS3/PSF3 family. {ECO:0000305}.
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DR   EMBL; CR380950; CAG58439.1; -; Genomic_DNA.
DR   RefSeq; XP_445528.1; XM_445528.1.
DR   AlphaFoldDB; Q6FW66; -.
DR   SMR; Q6FW66; -.
DR   STRING; 5478.XP_445528.1; -.
DR   EnsemblFungi; CAG58439; CAG58439; CAGL0D02596g.
DR   GeneID; 2887042; -.
DR   KEGG; cgr:CAGL0D02596g; -.
DR   CGD; CAL0128027; CAGL0D02596g.
DR   VEuPathDB; FungiDB:CAGL0D02596g; -.
DR   eggNOG; KOG1106; Eukaryota.
DR   HOGENOM; CLU_081646_0_1_1; -.
DR   InParanoid; Q6FW66; -.
DR   Proteomes; UP000002428; Chromosome D.
DR   GO; GO:0071162; C:CMG complex; IEA:EnsemblFungi.
DR   GO; GO:0000811; C:GINS complex; IEA:EnsemblFungi.
DR   GO; GO:0031298; C:replication fork protection complex; IEA:EnsemblFungi.
DR   GO; GO:0006268; P:DNA unwinding involved in DNA replication; IEA:EnsemblFungi.
DR   GO; GO:0000727; P:double-strand break repair via break-induced replication; IEA:EnsemblFungi.
DR   Gene3D; 1.20.58.2050; -; 1.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR010492; GINS_Psf3.
DR   InterPro; IPR038437; GINS_Psf3_sf.
DR   PANTHER; PTHR22768; PTHR22768; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   SUPFAM; SSF158573; SSF158573; 2.
PE   3: Inferred from homology;
KW   DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..249
FT                   /note="DNA replication complex GINS protein PSF3"
FT                   /id="PRO_0000278417"
FT   REGION          177..209
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   249 AA;  27775 MW;  19CA87664A5B4563 CRC64;
     MGYYDIDDIL VDSTEVPCKF NYEIPGLGYL ENNPGKPIRK NTKLSLPLWL ARVLAIVGAD
     SQEQEDMDPN AEEEDGGDAF VELLTPDMFS NKVINAIKTD PKSLDLHAIN PYFLDMALKW
     IALYSDKDLG EIVYELLLER AQQINNYASS VSIDTEYGNK YRSALLDALR LQQNSANEDR
     SGPLASINGT SSLTTRSANN SGIGSSVGTS QATNLAASTR FLLKLDEFER QLYKDTHDSY
     RDTKKWVSK