ID   PSF3_CRYNB              Reviewed;         189 AA.
AC   P0CQ33; Q55KV0; Q5KAM9;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=DNA replication complex GINS protein PSF3;
GN   Name=PSF3; OrderedLocusNames=CNBJ2330;
OS   Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
OS   (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=283643;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B-3501A;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       SLD5, PSF1, PSF2 and PSF3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GINS3/PSF3 family. {ECO:0000305}.
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DR   EMBL; AAEY01000050; EAL18310.1; -; Genomic_DNA.
DR   RefSeq; XP_772957.1; XM_767864.1.
DR   AlphaFoldDB; P0CQ33; -.
DR   SMR; P0CQ33; -.
DR   EnsemblFungi; ALO60904; ALO60904; CNJ01135.
DR   EnsemblFungi; EAL18310; EAL18310; CNBJ2330.
DR   GeneID; 4938576; -.
DR   KEGG; cnb:CNBJ2330; -.
DR   VEuPathDB; FungiDB:CNBJ2330; -.
DR   HOGENOM; CLU_081646_0_1_1; -.
DR   Proteomes; UP000001435; Chromosome 10.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.58.2050; -; 1.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR010492; GINS_Psf3.
DR   InterPro; IPR038437; GINS_Psf3_sf.
DR   PANTHER; PTHR22768; PTHR22768; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   SUPFAM; SSF158573; SSF158573; 1.
PE   3: Inferred from homology;
KW   DNA replication; Nucleus.
FT   CHAIN           1..189
FT                   /note="DNA replication complex GINS protein PSF3"
FT                   /id="PRO_0000410226"
SQ   SEQUENCE   189 AA;  21246 MW;  7C7A3E55F5FD9EE8 CRC64;
     MEDDYFSITS ILADNHKMSC TFALDAEGLG YLEGSTENDI HEGTKVELPF WLAQTLSVNQ
     FTTFTLPLPY SSRVQSALVA SPVSVKLSNL VGGNGWWYRW GKKLADMLED EQATNIRNML
     LRAFTGRLPT LQDLAAHHAS ADHTMPELST SKAEMFRDGM EGDERELFSI GQDSGRLFKA
     WYDRKKGSR