ID   PSF3_NEUCR              Reviewed;         218 AA.
AC   Q7S432;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=DNA replication complex GINS protein psf3;
DE   AltName: Full=DNA replication complex protein 3;
GN   Name=drc-3; Synonyms=psf3; ORFNames=NCU09561;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- FUNCTION: The GINS complex plays an essential role in the initiation of
CC       DNA replication. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the GINS complex which is a heterotetramer of
CC       div-26/sld5, drc-1/psf1, drc-2/psf2 and drc-3/psf3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GINS3/PSF3 family. {ECO:0000305}.
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DR   EMBL; CM002242; EAA30250.3; -; Genomic_DNA.
DR   RefSeq; XP_959486.3; XM_954393.3.
DR   AlphaFoldDB; Q7S432; -.
DR   SMR; Q7S432; -.
DR   STRING; 5141.EFNCRP00000009145; -.
DR   EnsemblFungi; EAA30250; EAA30250; NCU09561.
DR   GeneID; 3875633; -.
DR   KEGG; ncr:NCU09561; -.
DR   VEuPathDB; FungiDB:NCU09561; -.
DR   HOGENOM; CLU_081646_0_2_1; -.
DR   InParanoid; Q7S432; -.
DR   Proteomes; UP000001805; Chromosome 7, Linkage Group VII.
DR   GO; GO:0000811; C:GINS complex; IBA:GO_Central.
DR   GO; GO:1902975; P:mitotic DNA replication initiation; IBA:GO_Central.
DR   Gene3D; 1.20.58.2050; -; 1.
DR   InterPro; IPR021151; GINS_A.
DR   InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR   InterPro; IPR010492; GINS_Psf3.
DR   InterPro; IPR038437; GINS_Psf3_sf.
DR   PANTHER; PTHR22768; PTHR22768; 1.
DR   Pfam; PF05916; Sld5; 1.
DR   SUPFAM; SSF158573; SSF158573; 1.
PE   3: Inferred from homology;
KW   DNA replication; Nucleus; Reference proteome.
FT   CHAIN           1..218
FT                   /note="DNA replication complex GINS protein psf3"
FT                   /id="PRO_0000278425"
FT   REGION          147..182
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   218 AA;  23476 MW;  8B7F6A19E46C7C34 CRC64;
     MSYYDIDAIL TDAEKIPCTF QIDVPDLGYL DNQPGHTLKS GSRVALPIWL AEMLAIANTG
     AVDMDDPSQS SKSFITFDLP PALGNDVVQA LKADPRSVPL RDQSAHFYAL ATHMMELSEE
     PELSAVLRKT FVSRAAEIAL HARKVGGGGS SYHGRDGGGA GGKGKGKATK DDNASNLGVG
     GAGEDFLRGL DEWERKLFRS AHDGTKASKE WMENVKKR