ID   PSIO_DICDI              Reviewed;         750 AA.
AC   Q54VS4;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Protein psiO;
DE   Flags: Precursor;
GN   Name=psiO; ORFNames=DDB_G0280167;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the prespore-cell-inducing factor family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000035; EAL67310.1; -; Genomic_DNA.
DR   RefSeq; XP_641281.1; XM_636189.1.
DR   AlphaFoldDB; Q54VS4; -.
DR   PaxDb; Q54VS4; -.
DR   PRIDE; Q54VS4; -.
DR   EnsemblProtists; EAL67310; EAL67310; DDB_G0280167.
DR   GeneID; 8622413; -.
DR   KEGG; ddi:DDB_G0280167; -.
DR   dictyBase; DDB_G0280167; psiO.
DR   eggNOG; ENOG502REBK; Eukaryota.
DR   HOGENOM; CLU_024170_0_0_1; -.
DR   InParanoid; Q54VS4; -.
DR   OMA; THIPINC; -.
DR   PhylomeDB; Q54VS4; -.
DR   PRO; PR:Q54VS4; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR011874; Fibro_Slime.
DR   InterPro; IPR037524; PA14/GLEYA.
DR   InterPro; IPR011658; PA14_dom.
DR   Pfam; PF07691; PA14; 1.
DR   TIGRFAMs; TIGR02148; Fibro_Slime; 1.
DR   PROSITE; PS51820; PA14; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..750
FT                   /note="Protein psiO"
FT                   /id="PRO_0000327555"
FT   TOPO_DOM        23..688
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        689..709
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        710..750
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          140..286
FT                   /note="PA14"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01164"
FT   REGION          727..750
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        129
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        447
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        506
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        554
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        571
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        659
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   750 AA;  81772 MW;  D2879C6C25F08832 CRC64;
     MKEKIKLSLL ILTSIILAVA NSQTQPKTLA MTATVYDQHT FYNDNFENQG PAYLTKNMVV
     SKLDKTLKIP QLVSLDINVE GKTGVNYFGT MYNPKLFKYF FSENTNASPD DKNSGKNFPL
     LMDLILTLNE TSGAYEFSKQ EYFPINGKGF NDPSYKVPPK YKADSPNVDW FKMAGGGYSQ
     NNYNYCIKLN SKFTYFNKGE VFNFRGDDDV WVFIDNRLVV DLGGLHTAET ANIKLKDITN
     PPLQTNKIYD LDFFYCERRA TGSSIQLSTT LEIFCVDDYC GVCNGDGTSC CTSSTCEDNN
     ACTIDKCPKL GSVAPGKFTK DDCVYSEVVC PIESNQCLRP YCDPKEGCKT SPVECVNGNI
     DKCFEQFGSC DSSLGCQYNY KCNAYGKCNL GCSGGQCKVK TSEQCSEEFG NDPCYTYSCD
     VELGCVRTEK CSQEDAKLCT INTCLKNVTR EDDRCELVSI QEECNCCAGH TVDPCQLPGC
     GEPGECKPVD KIIDDNNLCT IDKCENGTIT HTPVKCGGCS ICDSKTGQCV INPPICDDDN
     VCTIDTCSLV ENPNGSIDGV CSNKIFDCAS NDTDLCNIWT CDANNGGCQS IKKVCDDPSP
     CLVSKCEPST GQCVDSPRTC DHGGAFCLIS ECDERLGCIV YNRQCASDNR KCQAGVCVNG
     TSSEEGHCTS VDYDPLPFGC NTAAVVSTAV IAGVTVAAVV GLGIFLYGGK KGYDYYQDNK
     SKGMTGANSN PLYKESGNAG QNPLYNDNNL