PSK1_ARATH
ID PSK1_ARATH Reviewed; 87 AA.
AC Q9LMY9; Q7PCB8; Q8W5R0;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 28-FEB-2003, sequence version 3.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Phytosulfokines 1;
DE Short=AtPSK1;
DE Contains:
DE RecName: Full=Phytosulfokine-alpha;
DE Short=PSK-alpha;
DE Short=Phytosulfokine-a;
DE Contains:
DE RecName: Full=Phytosulfokine-beta;
DE Short=PSK-beta;
DE Short=Phytosulfokine-b;
DE Flags: Precursor;
GN Name=PSK1; OrderedLocusNames=At1g13590; ORFNames=F21F23.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11706167; DOI=10.1104/pp.010452;
RA Yang H., Matsubayashi Y., Nakamura K., Sakagami Y.;
RT "Diversity of Arabidopsis genes encoding precursors for phytosulfokine, a
RT peptide growth factor.";
RL Plant Physiol. 127:842-851(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION.
RA Lorbiecke R., Sauter M.M.;
RT "Comparative analysis of PSK peptide growth factor precursor homologs.";
RL Plant Sci. 163:321-332(2002).
RN [6]
RP TISSUE SPECIFICITY.
RX PubMed=16829587; DOI=10.1104/pp.106.081109;
RA Matsubayashi Y., Ogawa M., Kihara H., Niwa M., Sakagami Y.;
RT "Disruption and overexpression of Arabidopsis phytosulfokine receptor gene
RT affects cellular longevity and potential for growth.";
RL Plant Physiol. 142:45-53(2006).
CC -!- FUNCTION: Promotes plant cell differentiation, organogenesis and
CC somatic embryogenesis as well as cell proliferation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed only in roots.
CC {ECO:0000269|PubMed:16829587}.
CC -!- PTM: Sulfation is important for activity and for the binding to a
CC putative membrane receptor. {ECO:0000250}.
CC -!- PTM: PSK-beta is produced from PSK-alpha by exopeptidase digestion.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the phytosulfokine family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF81285.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AB074572; BAB72176.2; -; Genomic_DNA.
DR EMBL; AC027656; AAF81285.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE29039.1; -; Genomic_DNA.
DR EMBL; AK176091; BAD43854.1; -; mRNA.
DR EMBL; BK000111; DAA00275.1; -; mRNA.
DR RefSeq; NP_172816.2; NM_101229.3.
DR AlphaFoldDB; Q9LMY9; -.
DR STRING; 3702.AT1G13590.1; -.
DR PaxDb; Q9LMY9; -.
DR PRIDE; Q9LMY9; -.
DR ProteomicsDB; 248755; -.
DR EnsemblPlants; AT1G13590.1; AT1G13590.1; AT1G13590.
DR GeneID; 837920; -.
DR Gramene; AT1G13590.1; AT1G13590.1; AT1G13590.
DR KEGG; ath:AT1G13590; -.
DR Araport; AT1G13590; -.
DR TAIR; locus:2009917; AT1G13590.
DR HOGENOM; CLU_165727_1_0_1; -.
DR InParanoid; Q9LMY9; -.
DR OMA; RDGVECK; -.
DR OrthoDB; 1612519at2759; -.
DR PhylomeDB; Q9LMY9; -.
DR PRO; PR:Q9LMY9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LMY9; baseline and differential.
DR Genevisible; Q9LMY9; AT.
DR GO; GO:0031012; C:extracellular matrix; ISS:TAIR.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008283; P:cell population proliferation; IEA:InterPro.
DR InterPro; IPR009438; Phytosulfokine.
DR PANTHER; PTHR33285; PTHR33285; 1.
DR Pfam; PF06404; PSK; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Differentiation; Growth factor; Reference proteome;
KW Secreted; Signal; Sulfation.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT PROPEP 25..76
FT /evidence="ECO:0000255"
FT /id="PRO_0000024081"
FT PEPTIDE 77..81
FT /note="Phytosulfokine-alpha"
FT /evidence="ECO:0000250"
FT /id="PRO_0000024082"
FT PEPTIDE 77..80
FT /note="Phytosulfokine-beta"
FT /evidence="ECO:0000250"
FT /id="PRO_0000024083"
FT PROPEP 82..87
FT /evidence="ECO:0000255"
FT /id="PRO_0000024084"
FT REGION 31..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 77
FT /note="Sulfotyrosine"
FT /evidence="ECO:0000250"
FT MOD_RES 79
FT /note="Sulfotyrosine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 87 AA; 9653 MW; 2EE440EB8BFCF842 CRC64;
MMKTKSEVLI FFFTLVLLLS MASSVILRED GFAPPKPSPT THEKASTKGD RDGVECKNSD
SEEECLVKKT VAAHTDYIYT QDLNLSP
