PSK2_ARATH
ID PSK2_ARATH Reviewed; 87 AA.
AC O81003; Q7PCC1;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Phytosulfokines 2;
DE Short=AtPSK2;
DE Contains:
DE RecName: Full=Phytosulfokine-alpha;
DE Short=PSK-alpha;
DE Short=Phytosulfokine-a;
DE Contains:
DE RecName: Full=Phytosulfokine-beta;
DE Short=PSK-beta;
DE Short=Phytosulfokine-b;
DE Flags: Precursor;
GN Name=PSK2; OrderedLocusNames=At2g22860; ORFNames=T20K9.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11706167; DOI=10.1104/pp.010452;
RA Yang H., Matsubayashi Y., Nakamura K., Sakagami Y.;
RT "Diversity of Arabidopsis genes encoding precursors for phytosulfokine, a
RT peptide growth factor.";
RL Plant Physiol. 127:842-851(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP IDENTIFICATION.
RA Lorbiecke R., Sauter M.M.;
RT "Comparative analysis of PSK peptide growth factor precursor homologs.";
RL Plant Sci. 163:321-332(2002).
RN [7]
RP TISSUE SPECIFICITY.
RX PubMed=16829587; DOI=10.1104/pp.106.081109;
RA Matsubayashi Y., Ogawa M., Kihara H., Niwa M., Sakagami Y.;
RT "Disruption and overexpression of Arabidopsis phytosulfokine receptor gene
RT affects cellular longevity and potential for growth.";
RL Plant Physiol. 142:45-53(2006).
RN [8]
RP INDUCTION BY FUNGAL INFECTION.
RX PubMed=20403122; DOI=10.1111/j.1399-3054.2010.01371.x;
RA Loivamaki M., Stuhrwohldt N., Deeken R., Steffens B., Roitsch T.,
RA Hedrich R., Sauter M.;
RT "A role for PSK signaling in wounding and microbial interactions in
RT Arabidopsis.";
RL Physiol. Plantarum 139:348-357(2010).
CC -!- FUNCTION: Promotes plant cell differentiation, organogenesis and
CC somatic embryogenesis as well as cell proliferation.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Expressed in stems, roots and leaves.
CC {ECO:0000269|PubMed:16829587}.
CC -!- INDUCTION: Up-regulated by fungal infection.
CC {ECO:0000269|PubMed:20403122}.
CC -!- PTM: Sulfation is important for activity and for the binding to a
CC putative membrane receptor. {ECO:0000250}.
CC -!- PTM: PSK-beta is an enzymatic derivative of PSK-alpha.
CC -!- SIMILARITY: Belongs to the phytosulfokine family. {ECO:0000305}.
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DR EMBL; AB029344; BAB72148.1; -; mRNA.
DR EMBL; AB052752; BAB72151.1; -; Genomic_DNA.
DR EMBL; AC004786; AAC32433.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07366.1; -; Genomic_DNA.
DR EMBL; AK118870; BAC43456.1; -; mRNA.
DR EMBL; BT004954; AAO50487.1; -; mRNA.
DR EMBL; BK000108; DAA00272.1; -; mRNA.
DR PIR; G84617; G84617.
DR RefSeq; NP_179871.1; NM_127851.5.
DR AlphaFoldDB; O81003; -.
DR STRING; 3702.AT2G22860.1; -.
DR PaxDb; O81003; -.
DR PRIDE; O81003; -.
DR EnsemblPlants; AT2G22860.1; AT2G22860.1; AT2G22860.
DR GeneID; 816817; -.
DR Gramene; AT2G22860.1; AT2G22860.1; AT2G22860.
DR KEGG; ath:AT2G22860; -.
DR Araport; AT2G22860; -.
DR TAIR; locus:2059216; AT2G22860.
DR eggNOG; ENOG502S6XU; Eukaryota.
DR HOGENOM; CLU_165727_0_1_1; -.
DR InParanoid; O81003; -.
DR OMA; NESCEGA; -.
DR OrthoDB; 1620923at2759; -.
DR PhylomeDB; O81003; -.
DR PRO; PR:O81003; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O81003; baseline and differential.
DR Genevisible; O81003; AT.
DR GO; GO:0031012; C:extracellular matrix; ISS:TAIR.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; ISS:TAIR.
DR GO; GO:0008283; P:cell population proliferation; IEA:InterPro.
DR InterPro; IPR009438; Phytosulfokine.
DR PANTHER; PTHR33285; PTHR33285; 1.
DR Pfam; PF06404; PSK; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Differentiation; Growth factor; Reference proteome;
KW Secreted; Signal; Sulfation.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT PROPEP 23..77
FT /id="PRO_0000024085"
FT PEPTIDE 78..82
FT /note="Phytosulfokine-alpha"
FT /id="PRO_0000024086"
FT PEPTIDE 78..81
FT /note="Phytosulfokine-beta"
FT /id="PRO_0000024087"
FT PROPEP 83..87
FT /id="PRO_0000024088"
FT MOD_RES 78
FT /note="Sulfotyrosine"
FT /evidence="ECO:0000250"
FT MOD_RES 80
FT /note="Sulfotyrosine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 87 AA; 9627 MW; 62D1D4908CA40CDF CRC64;
MANVSALLTI ALLLCSTLMC TARPEPAISI SITTAADPCN MEKKIEGKLD DMHMVDENCG
ADDEDCLMRR TLVAHTDYIY TQKKKHP
