PSK3_ARATH
ID PSK3_ARATH Reviewed; 79 AA.
AC Q9M2Y0; Q7PCC0; Q8VWK1;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 29-AUG-2001, sequence version 2.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Phytosulfokines 3;
DE Short=AtPSK3;
DE Contains:
DE RecName: Full=Phytosulfokine-alpha;
DE Short=PSK-alpha;
DE Short=Phytosulfokine-a;
DE Contains:
DE RecName: Full=Phytosulfokine-beta;
DE Short=PSK-beta;
DE Short=Phytosulfokine-b;
DE Flags: Precursor;
GN Name=PSK3; Synonyms=PSK4; OrderedLocusNames=At3g49780; ORFNames=T16K5.130;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11706167; DOI=10.1104/pp.010452;
RA Yang H., Matsubayashi Y., Nakamura K., Sakagami Y.;
RT "Diversity of Arabidopsis genes encoding precursors for phytosulfokine, a
RT peptide growth factor.";
RL Plant Physiol. 127:842-851(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP IDENTIFICATION.
RA Lorbiecke R., Sauter M.M.;
RT "Comparative analysis of PSK peptide growth factor precursor homologs.";
RL Plant Sci. 163:321-332(2002).
RN [7]
RP TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=16829587; DOI=10.1104/pp.106.081109;
RA Matsubayashi Y., Ogawa M., Kihara H., Niwa M., Sakagami Y.;
RT "Disruption and overexpression of Arabidopsis phytosulfokine receptor gene
RT affects cellular longevity and potential for growth.";
RL Plant Physiol. 142:45-53(2006).
RN [8]
RP INDUCTION BY WOUNDING.
RX PubMed=20403122; DOI=10.1111/j.1399-3054.2010.01371.x;
RA Loivamaki M., Stuhrwohldt N., Deeken R., Steffens B., Roitsch T.,
RA Hedrich R., Sauter M.;
RT "A role for PSK signaling in wounding and microbial interactions in
RT Arabidopsis.";
RL Physiol. Plantarum 139:348-357(2010).
CC -!- FUNCTION: Promotes plant cell differentiation, organogenesis and
CC somatic embryogenesis as well as cell proliferation.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Expressed in roots, mature leaves, stems, flowers
CC and siliques. Most abundant in vascular bundles.
CC {ECO:0000269|PubMed:16829587}.
CC -!- INDUCTION: Up-regulated by wounding. {ECO:0000269|PubMed:16829587,
CC ECO:0000269|PubMed:20403122}.
CC -!- PTM: Sulfation is important for activity and for the binding to a
CC putative membrane receptor. {ECO:0000250}.
CC -!- PTM: PSK-beta is an enzymatic derivative of PSK-alpha.
CC -!- SIMILARITY: Belongs to the phytosulfokine family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB66916.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB050627; BAB72150.1; -; Genomic_DNA.
DR EMBL; AB029820; BAB72149.1; -; mRNA.
DR EMBL; AL132965; CAB66916.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002686; AEE78589.1; -; Genomic_DNA.
DR EMBL; BT001985; AAN71996.1; -; mRNA.
DR EMBL; BT006496; AAP21304.1; -; mRNA.
DR EMBL; AY088006; AAM65552.1; -; mRNA.
DR EMBL; BK000109; DAA00273.1; -; mRNA.
DR PIR; T46044; T46044.
DR RefSeq; NP_566926.1; NM_114838.2.
DR AlphaFoldDB; Q9M2Y0; -.
DR STRING; 3702.AT3G49780.1; -.
DR PaxDb; Q9M2Y0; -.
DR PRIDE; Q9M2Y0; -.
DR ProteomicsDB; 249359; -.
DR EnsemblPlants; AT3G49780.1; AT3G49780.1; AT3G49780.
DR GeneID; 824140; -.
DR Gramene; AT3G49780.1; AT3G49780.1; AT3G49780.
DR KEGG; ath:AT3G49780; -.
DR Araport; AT3G49780; -.
DR TAIR; locus:2097345; AT3G49780.
DR eggNOG; ENOG502S6XU; Eukaryota.
DR HOGENOM; CLU_165727_0_1_1; -.
DR InParanoid; Q9M2Y0; -.
DR OMA; SCKGVKE; -.
DR PhylomeDB; Q9M2Y0; -.
DR PRO; PR:Q9M2Y0; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M2Y0; baseline and differential.
DR Genevisible; Q9M2Y0; AT.
DR GO; GO:0031012; C:extracellular matrix; IDA:TAIR.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; ISS:TAIR.
DR GO; GO:0008283; P:cell population proliferation; IEA:InterPro.
DR GO; GO:0071456; P:cellular response to hypoxia; HEP:TAIR.
DR InterPro; IPR009438; Phytosulfokine.
DR PANTHER; PTHR33285; PTHR33285; 1.
DR Pfam; PF06404; PSK; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Differentiation; Growth factor; Reference proteome;
KW Secreted; Signal; Sulfation.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT PROPEP 22..70
FT /id="PRO_0000024089"
FT PEPTIDE 71..75
FT /note="Phytosulfokine-alpha"
FT /id="PRO_0000024090"
FT PEPTIDE 71..74
FT /note="Phytosulfokine-beta"
FT /id="PRO_0000024091"
FT PROPEP 76..79
FT /id="PRO_0000024092"
FT MOD_RES 71
FT /note="Sulfotyrosine"
FT /evidence="ECO:0000250"
FT MOD_RES 73
FT /note="Sulfotyrosine"
FT /evidence="ECO:0000250"
FT VARIANT 66
FT /note="V -> L"
SQ SEQUENCE 79 AA; 8897 MW; 4AC71C25912F30CF CRC64;
MGKFTTIFIM ALLLCSTLTY AARLTPTTTT ALSRENSVKE IEGDKVEEES CNGIGEEECL
IRRSLVLHTD YIYTQNHKP
