PSK5_ARATH
ID PSK5_ARATH Reviewed; 77 AA.
AC Q9FEB4; Q7PCB7;
DT 29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Phytosulfokines 5;
DE Short=AtPSK5;
DE Contains:
DE RecName: Full=Phytosulfokine-alpha;
DE Short=PSK-alpha;
DE Short=Phytosulfokine-a;
DE Contains:
DE RecName: Full=Phytosulfokine-beta;
DE Short=PSK-beta;
DE Short=Phytosulfokine-b;
DE Flags: Precursor;
GN Name=PSK5; OrderedLocusNames=At5g65870; ORFNames=K14B20.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11706167; DOI=10.1104/pp.010452;
RA Yang H., Matsubayashi Y., Nakamura K., Sakagami Y.;
RT "Diversity of Arabidopsis genes encoding precursors for phytosulfokine, a
RT peptide growth factor.";
RL Plant Physiol. 127:842-851(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP IDENTIFICATION.
RA Lorbiecke R., Sauter M.M.;
RT "Comparative analysis of PSK peptide growth factor precursor homologs.";
RL Plant Sci. 163:321-332(2002).
RN [7]
RP TISSUE SPECIFICITY.
RX PubMed=16829587; DOI=10.1104/pp.106.081109;
RA Matsubayashi Y., Ogawa M., Kihara H., Niwa M., Sakagami Y.;
RT "Disruption and overexpression of Arabidopsis phytosulfokine receptor gene
RT affects cellular longevity and potential for growth.";
RL Plant Physiol. 142:45-53(2006).
RN [8]
RP INDUCTION BY FUNGAL INFECTION AND WOUNDING.
RX PubMed=20403122; DOI=10.1111/j.1399-3054.2010.01371.x;
RA Loivamaki M., Stuhrwohldt N., Deeken R., Steffens B., Roitsch T.,
RA Hedrich R., Sauter M.;
RT "A role for PSK signaling in wounding and microbial interactions in
RT Arabidopsis.";
RL Physiol. Plantarum 139:348-357(2010).
RN [9]
RP INDUCTION.
RX PubMed=24158907; DOI=10.1126/science.1240667;
RA Heyman J., Cools T., Vandenbussche F., Heyndrickx K.S., Van Leene J.,
RA Vercauteren I., Vanderauwera S., Vandepoele K., De Jaeger G.,
RA Van Der Straeten D., De Veylder L.;
RT "ERF115 controls root quiescent center cell division and stem cell
RT replenishment.";
RL Science 342:860-863(2013).
CC -!- FUNCTION: Promotes plant cell differentiation, organogenesis and
CC somatic embryogenesis as well as cell proliferation (By similarity).
CC May be involved in the low quiescent center cell proliferation.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in stems, roots, mature leaves and
CC flowers. Most abundant in vascular bundles.
CC {ECO:0000269|PubMed:16829587}.
CC -!- INDUCTION: Up-regulated by ERF115, by brassinosteroid treatment,
CC wounding and fungal infection. {ECO:0000269|PubMed:20403122,
CC ECO:0000269|PubMed:24158907}.
CC -!- PTM: Sulfation is important for activity and for the binding to a
CC putative membrane receptor. {ECO:0000250}.
CC -!- PTM: PSK-beta is an enzymatic derivative of PSK-alpha. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the phytosulfokine family. {ECO:0000305}.
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DR EMBL; AB074574; BAB72178.1; -; Genomic_DNA.
DR EMBL; AB018108; BAB11134.1; -; Genomic_DNA.
DR EMBL; CP002688; AED98117.1; -; Genomic_DNA.
DR EMBL; AF325020; AAG40372.1; -; mRNA.
DR EMBL; AY088723; AAM67041.1; -; mRNA.
DR EMBL; BK000112; DAA00276.1; -; mRNA.
DR RefSeq; NP_201388.1; NM_125984.4.
DR AlphaFoldDB; Q9FEB4; -.
DR STRING; 3702.AT5G65870.1; -.
DR PaxDb; Q9FEB4; -.
DR PRIDE; Q9FEB4; -.
DR ProteomicsDB; 248893; -.
DR EnsemblPlants; AT5G65870.1; AT5G65870.1; AT5G65870.
DR GeneID; 836716; -.
DR Gramene; AT5G65870.1; AT5G65870.1; AT5G65870.
DR KEGG; ath:AT5G65870; -.
DR Araport; AT5G65870; -.
DR TAIR; locus:2152084; AT5G65870.
DR HOGENOM; CLU_165727_0_1_1; -.
DR InParanoid; Q9FEB4; -.
DR OMA; VETHHTE; -.
DR OrthoDB; 1620923at2759; -.
DR PhylomeDB; Q9FEB4; -.
DR PRO; PR:Q9FEB4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FEB4; baseline and differential.
DR Genevisible; Q9FEB4; AT.
DR GO; GO:0031012; C:extracellular matrix; ISS:TAIR.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; ISS:TAIR.
DR GO; GO:0008283; P:cell population proliferation; IEA:InterPro.
DR InterPro; IPR009438; Phytosulfokine.
DR PANTHER; PTHR33285; PTHR33285; 1.
DR Pfam; PF06404; PSK; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Differentiation; Growth factor; Reference proteome;
KW Secreted; Signal; Sulfation.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT PROPEP 25..68
FT /evidence="ECO:0000255"
FT /id="PRO_0000024097"
FT PEPTIDE 69..73
FT /note="Phytosulfokine-alpha"
FT /evidence="ECO:0000250"
FT /id="PRO_0000024098"
FT PEPTIDE 69..72
FT /note="Phytosulfokine-beta"
FT /evidence="ECO:0000250"
FT /id="PRO_0000024099"
FT PROPEP 74..77
FT /evidence="ECO:0000255"
FT /id="PRO_0000024100"
FT MOD_RES 69
FT /note="Sulfotyrosine"
FT /evidence="ECO:0000250"
FT MOD_RES 71
FT /note="Sulfotyrosine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 77 AA; 8749 MW; 4AB0E8D9A6CDB7A7 CRC64;
MVKFTTFLCI IALLLCSTLT HASARLNPTS VYPEENSFKK LEQGEVICEG VGEEECFLIR
RTLVAHTDYI YTQNHNP
