PSK6_ARATH
ID PSK6_ARATH Reviewed; 81 AA.
AC Q8LA14; Q7PCC2; Q8W5Q9;
DT 28-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT 28-FEB-2003, sequence version 2.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Putative phytosulfokines 6;
DE Short=AtPSK3_2;
DE Short=AtPSK6;
DE Contains:
DE RecName: Full=Phytosulfokine-alpha-like;
DE Short=PSK-alpha-like;
DE Short=Phytosulfokine-a-like;
DE Contains:
DE RecName: Full=Phytosulfokine-beta;
DE Short=PSK-beta;
DE Short=Phytosulfokine-b;
DE Flags: Precursor;
GN Name=PSK6; Synonyms=PSK3; OrderedLocusNames=At3g44735; ORFNames=T32N15.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11706167; DOI=10.1104/pp.010452;
RA Yang H., Matsubayashi Y., Nakamura K., Sakagami Y.;
RT "Diversity of Arabidopsis genes encoding precursors for phytosulfokine, a
RT peptide growth factor.";
RL Plant Physiol. 127:842-851(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION.
RA Lorbiecke R., Sauter M.M.;
RT "Comparative analysis of PSK peptide growth factor precursor homologs.";
RL Plant Sci. 163:321-332(2002).
RN [6]
RP TISSUE SPECIFICITY.
RX PubMed=16829587; DOI=10.1104/pp.106.081109;
RA Matsubayashi Y., Ogawa M., Kihara H., Niwa M., Sakagami Y.;
RT "Disruption and overexpression of Arabidopsis phytosulfokine receptor gene
RT affects cellular longevity and potential for growth.";
RL Plant Physiol. 142:45-53(2006).
CC -!- FUNCTION: Promotes plant cell differentiation, organogenesis and
CC somatic embryogenesis as well as cell proliferation. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves, stems, flowers and
CC siliques. Most abundant in vascular bundles and in root tips.
CC {ECO:0000269|PubMed:16829587}.
CC -!- PTM: Sulfation is important for activity and for the binding to a
CC putative membrane receptor. {ECO:0000250}.
CC -!- PTM: PSK-beta is an enzymatic derivative of PSK-alpha. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the phytosulfokine family. {ECO:0000305}.
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DR EMBL; AB074573; BAB72177.2; -; Genomic_DNA.
DR EMBL; AC002534; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002686; AEE77941.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77942.1; -; Genomic_DNA.
DR EMBL; AY088090; AAM65636.1; -; mRNA.
DR EMBL; BK000107; DAA00271.1; -; Genomic_DNA.
DR RefSeq; NP_001190011.1; NM_001203082.1.
DR RefSeq; NP_566871.1; NM_114342.3.
DR AlphaFoldDB; Q8LA14; -.
DR STRING; 3702.AT3G44735.2; -.
DR PaxDb; Q8LA14; -.
DR PRIDE; Q8LA14; -.
DR ProteomicsDB; 249361; -.
DR EnsemblPlants; AT3G44735.1; AT3G44735.1; AT3G44735.
DR EnsemblPlants; AT3G44735.2; AT3G44735.2; AT3G44735.
DR GeneID; 823603; -.
DR Gramene; AT3G44735.1; AT3G44735.1; AT3G44735.
DR Gramene; AT3G44735.2; AT3G44735.2; AT3G44735.
DR KEGG; ath:AT3G44735; -.
DR Araport; AT3G44735; -.
DR TAIR; locus:505006386; AT3G44735.
DR eggNOG; ENOG502S9S0; Eukaryota.
DR HOGENOM; CLU_132277_1_0_1; -.
DR InParanoid; Q8LA14; -.
DR OMA; GLEEYSC; -.
DR OrthoDB; 1629097at2759; -.
DR PhylomeDB; Q8LA14; -.
DR PRO; PR:Q8LA14; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8LA14; baseline and differential.
DR Genevisible; Q8LA14; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0008283; P:cell population proliferation; IEA:InterPro.
DR InterPro; IPR009438; Phytosulfokine.
DR PANTHER; PTHR33285; PTHR33285; 1.
DR Pfam; PF06404; PSK; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Differentiation; Growth factor; Reference proteome;
KW Secreted; Signal; Sulfation.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT PROPEP 21..72
FT /evidence="ECO:0000255"
FT /id="PRO_0000024101"
FT PEPTIDE 73..77
FT /note="Phytosulfokine-alpha-like"
FT /evidence="ECO:0000255"
FT /id="PRO_0000024102"
FT PEPTIDE 73..76
FT /note="Phytosulfokine-beta"
FT /evidence="ECO:0000255"
FT /id="PRO_0000024103"
FT PROPEP 78..81
FT /evidence="ECO:0000255"
FT /id="PRO_0000024104"
FT MOD_RES 73
FT /note="Sulfotyrosine"
FT /evidence="ECO:0000250"
FT MOD_RES 75
FT /note="Sulfotyrosine"
FT /evidence="ECO:0000250"
FT CONFLICT 4
FT /note="S -> T (in Ref. 4; AAM65636)"
FT /evidence="ECO:0000305"
FT CONFLICT 22
FT /note="R -> H (in Ref. 4; AAM65636)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 81 AA; 9292 MW; DCCD2A2A08461729 CRC64;
MKQSLCLAVL FLILSTSSSA IRRGKEDQEI NPLVSATSVE EDSVNKLMGM EYCGEGDEEC
LRRRMMTESH LDYIYTQHHK H
