PSL1_SCHPO
ID PSL1_SCHPO Reviewed; 243 AA.
AC O42979;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=PHO85 cyclin-like protein psl1;
GN Name=psl1; ORFNames=SPBC20F10.10;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Cyclin partner of the cyclin-dependent kinase (CDK) pef1
CC (PHO85 homolog). {ECO:0000250}.
CC -!- SUBUNIT: Forms a cyclin-CDK complex with pef1. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}. Note=Localizes at the barrier septum.
CC -!- SIMILARITY: Belongs to the cyclin family. PHO80 subfamily.
CC {ECO:0000305}.
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DR EMBL; CU329671; CAA16850.1; -; Genomic_DNA.
DR PIR; T39881; T39881.
DR RefSeq; NP_596374.1; NM_001022295.2.
DR AlphaFoldDB; O42979; -.
DR SMR; O42979; -.
DR BioGRID; 277273; 98.
DR STRING; 4896.SPBC20F10.10.1; -.
DR iPTMnet; O42979; -.
DR MaxQB; O42979; -.
DR PaxDb; O42979; -.
DR PRIDE; O42979; -.
DR EnsemblFungi; SPBC20F10.10.1; SPBC20F10.10.1:pep; SPBC20F10.10.
DR GeneID; 2540751; -.
DR KEGG; spo:SPBC20F10.10; -.
DR PomBase; SPBC20F10.10; psl1.
DR VEuPathDB; FungiDB:SPBC20F10.10; -.
DR eggNOG; KOG1674; Eukaryota.
DR HOGENOM; CLU_947164_0_0_1; -.
DR InParanoid; O42979; -.
DR OMA; MEESAYS; -.
DR PhylomeDB; O42979; -.
DR PRO; PR:O42979; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0032153; C:cell division site; HDA:PomBase.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0044732; C:mitotic spindle pole body; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; ISO:PomBase.
DR GO; GO:0019901; F:protein kinase binding; IEA:InterPro.
DR GO; GO:1905412; P:negative regulation of mitotic cohesin loading; IGI:PomBase.
DR GO; GO:1901987; P:regulation of cell cycle phase transition; NAS:PomBase.
DR GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR InterPro; IPR012389; Cyclin_P/U.
DR InterPro; IPR013922; Cyclin_PHO80-like.
DR PANTHER; PTHR15615; PTHR15615; 2.
DR Pfam; PF08613; Cyclin; 1.
DR PIRSF; PIRSF027110; PREG; 1.
PE 3: Inferred from homology;
KW Cyclin; Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..243
FT /note="PHO85 cyclin-like protein psl1"
FT /id="PRO_0000374022"
FT REGION 211..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 243 AA; 27937 MW; 0C114E7E26D479D4 CRC64;
MSLAFTLLTS KDNTDEDEEH LELSSFNQEK LLEMISVFLS RLTRLNDSKQ EATESDQIPL
SPTSLKNPCL IFSAKNVPSI SIQAYLTRIL KYCPATNDVF LSVLIYLDRI VHHFHFTVFI
NSFNIHRFLI AGFTAASKFF SDVFYTNSRY AKVGGIPLHE LNHLELSFFV FNDFNLFISL
EDLQAYGDLL LSWYRQNGQN YNPTDVSCSI ESPISHTPQQ NQQDEQPRRP IMDRRLLSSH
SIG
