ID   PSMA1_STAA2             Reviewed;          21 AA.
AC   P0C7X9;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 23.
DE   RecName: Full=Phenol-soluble modulin alpha 1 peptide;
GN   Name=psmA1; OrderedLocusNames=SaurJH1_0486.4;
OS   Staphylococcus aureus (strain JH1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=359787;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JH1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Tomasz A., Richardson P.;
RT   "Complete sequence of chromosome of Staphylococcus aureus subsp. aureus
RT   JH1.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Peptide which can recruit, activate and subsequently lyse
CC       human neutrophils, thus eliminating the main cellular defense against
CC       infection. {ECO:0000250|UniProtKB:A9JX05}.
CC   -!- SIMILARITY: Belongs to the phenol-soluble modulin alpha peptides
CC       family. {ECO:0000305}.
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DR   EMBL; CP000736; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P0C7X9; -.
DR   SMR; P0C7X9; -.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR031429; PSM_alpha.
DR   Pfam; PF17063; PSMalpha; 1.
PE   3: Inferred from homology;
KW   Cytolysis; Virulence.
FT   PEPTIDE         1..21
FT                   /note="Phenol-soluble modulin alpha 1 peptide"
FT                   /id="PRO_0000345030"
SQ   SEQUENCE   21 AA;  2260 MW;  F291499952C7572D CRC64;
     MGIIAGIIKV IKSLIEQFTG K