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PSMA1_STAAN
ID   PSMA1_STAAN             Reviewed;          21 AA.
AC   P0C7Y7;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 24.
DE   RecName: Full=Phenol-soluble modulin alpha 1 peptide;
GN   Name=psmA1; OrderedLocusNames=SA0410.5;
OS   Staphylococcus aureus (strain N315).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N315;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- FUNCTION: Peptide which can recruit, activate and subsequently lyse
CC       human neutrophils, thus eliminating the main cellular defense against
CC       infection. {ECO:0000250|UniProtKB:A9JX05}.
CC   -!- SIMILARITY: Belongs to the phenol-soluble modulin alpha peptides
CC       family. {ECO:0000305}.
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DR   EMBL; BA000018; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P0C7Y7; -.
DR   SMR; P0C7Y7; -.
DR   Proteomes; UP000000751; Chromosome.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR031429; PSM_alpha.
DR   Pfam; PF17063; PSMalpha; 1.
PE   3: Inferred from homology;
KW   Cytolysis; Virulence.
FT   PEPTIDE         1..21
FT                   /note="Phenol-soluble modulin alpha 1 peptide"
FT                   /id="PRO_0000345038"
SQ   SEQUENCE   21 AA;  2260 MW;  F291499952C7572D CRC64;
     MGIIAGIIKV IKSLIEQFTG K
 
 
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