PSMA2_STAA8
ID PSMA2_STAA8 Reviewed; 21 AA.
AC P0C7Z3;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 22-JUL-2008, sequence version 1.
DT 25-MAY-2022, entry version 25.
DE RecName: Full=Phenol-soluble modulin alpha 2 peptide;
GN Name=psmA2; OrderedLocusNames=SAOUHSC_00411.3;
OS Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=93061;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 8325 / PS 47;
RA Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT "The Staphylococcus aureus NCTC 8325 genome.";
RL (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL D.C. (2006).
CC -!- FUNCTION: Peptide which can recruit, activate and subsequently lyse
CC human neutrophils, thus eliminating the main cellular defense against
CC infection. {ECO:0000250|UniProtKB:A9JX06}.
CC -!- SIMILARITY: Belongs to the phenol-soluble modulin alpha peptides
CC family. {ECO:0000305}.
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DR EMBL; CP000253; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; P0C7Z3; -.
DR Proteomes; UP000008816; Chromosome.
DR GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR InterPro; IPR031429; PSM_alpha.
DR Pfam; PF17063; PSMalpha; 1.
PE 3: Inferred from homology;
KW Cytolysis; Reference proteome; Virulence.
FT PEPTIDE 1..21
FT /note="Phenol-soluble modulin alpha 2 peptide"
FT /id="PRO_0000345046"
SQ SEQUENCE 21 AA; 2278 MW; E3D5498D1727572D CRC64;
MGIIAGIIKF IKGLIEKFTG K