ID   PSMA4_STAAE             Reviewed;          20 AA.
AC   P0C822; B9ZUX4;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=Phenol-soluble modulin alpha 4 peptide;
GN   Name=psmA4; OrderedLocusNames=NWMN_0417.1; ORFNames=NWMN_2616;
OS   Staphylococcus aureus (strain Newman).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=426430;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Newman;
RX   PubMed=17951380; DOI=10.1128/jb.01000-07;
RA   Baba T., Bae T., Schneewind O., Takeuchi F., Hiramatsu K.;
RT   "Genome sequence of Staphylococcus aureus strain Newman and comparative
RT   analysis of staphylococcal genomes: polymorphism and evolution of two major
RT   pathogenicity islands.";
RL   J. Bacteriol. 190:300-310(2008).
CC   -!- FUNCTION: Peptide which can recruit, activate and subsequently lyse
CC       human neutrophils, thus eliminating the main cellular defense against
CC       infection. {ECO:0000250|UniProtKB:A9JX08}.
CC   -!- SIMILARITY: Belongs to the phenol-soluble modulin alpha peptides
CC       family. {ECO:0000305}.
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DR   EMBL; AP009351; BAH22632.1; -; Genomic_DNA.
DR   AlphaFoldDB; P0C822; -.
DR   SMR; P0C822; -.
DR   EnsemblBacteria; BAH22632; BAH22632; NWMN_2616.
DR   KEGG; sae:NWMN_2616; -.
DR   HOGENOM; CLU_221892_0_0_9; -.
DR   Proteomes; UP000006386; Chromosome.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR031429; PSM_alpha.
DR   Pfam; PF17063; PSMalpha; 1.
PE   3: Inferred from homology;
KW   Cytolysis; Virulence.
FT   PEPTIDE         1..20
FT                   /note="Phenol-soluble modulin alpha 4 peptide"
FT                   /id="PRO_0000345078"
SQ   SEQUENCE   20 AA;  2172 MW;  6D59253C66E73D0E CRC64;
     MAIVGTIIKI IKAIIDIFAK