ID   PSMD9_BOVIN             Reviewed;         221 AA.
AC   Q3SZ19;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=26S proteasome non-ATPase regulatory subunit 9;
DE   AltName: Full=26S proteasome regulatory subunit p27;
GN   Name=PSMD9;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   SUBUNIT.
RX   PubMed=8621709; DOI=10.1074/jbc.271.6.3112;
RA   Demartino G.N., Proske R.J., Moomaw C.R., Strong A.A., Song X.,
RA   Hisamatsu H., Tanaka K., Slaughter C.A.;
RT   "Identification, purification, and characterization of a PA700-dependent
RT   activator of the proteasome.";
RL   J. Biol. Chem. 271:3112-3118(1996).
CC   -!- FUNCTION: Acts as a chaperone during the assembly of the 26S
CC       proteasome, specifically of the base subcomplex of the PA700/19S
CC       regulatory complex (RC). During the base subcomplex assembly is part of
CC       an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator
CC       trimer complex; PSMD9 is released during the further base assembly
CC       process.
CC   -!- SUBUNIT: Interacts with PSMC3. Part of a transient complex (modulator)
CC       containing PSMD9, PSMC6 and PSMC3 formed during the assembly of the 26S
CC       proteasome. {ECO:0000269|PubMed:8621709}.
CC   -!- SIMILARITY: Belongs to the proteasome subunit p27 family.
CC       {ECO:0000305}.
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DR   EMBL; BC103247; AAI03248.1; -; mRNA.
DR   RefSeq; NP_001029613.1; NM_001034441.2.
DR   AlphaFoldDB; Q3SZ19; -.
DR   SMR; Q3SZ19; -.
DR   CORUM; Q3SZ19; -.
DR   STRING; 9913.ENSBTAP00000029636; -.
DR   PaxDb; Q3SZ19; -.
DR   PRIDE; Q3SZ19; -.
DR   Ensembl; ENSBTAT00000029638; ENSBTAP00000029636; ENSBTAG00000004179.
DR   GeneID; 513315; -.
DR   KEGG; bta:513315; -.
DR   CTD; 5715; -.
DR   VEuPathDB; HostDB:ENSBTAG00000004179; -.
DR   VGNC; VGNC:53917; PSMD9.
DR   eggNOG; KOG3129; Eukaryota.
DR   GeneTree; ENSGT00390000004147; -.
DR   HOGENOM; CLU_073146_2_1_1; -.
DR   InParanoid; Q3SZ19; -.
DR   OMA; GCNIVPL; -.
DR   OrthoDB; 1405146at2759; -.
DR   TreeFam; TF105995; -.
DR   Proteomes; UP000009136; Chromosome 17.
DR   Bgee; ENSBTAG00000004179; Expressed in rumen papilla and 105 other tissues.
DR   ExpressionAtlas; Q3SZ19; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; IEA:Ensembl.
DR   GO; GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR040815; Nas2_N.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR041489; PDZ_6.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR035269; PSMD9.
DR   PANTHER; PTHR12651; PTHR12651; 1.
DR   Pfam; PF18265; Nas2_N; 1.
DR   Pfam; PF17820; PDZ_6; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF50156; SSF50156; 1.
PE   1: Evidence at protein level;
KW   Chaperone; Reference proteome.
FT   CHAIN           1..221
FT                   /note="26S proteasome non-ATPase regulatory subunit 9"
FT                   /id="PRO_0000251724"
FT   DOMAIN          108..193
FT                   /note="PDZ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          105..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..121
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   221 AA;  24266 MW;  42C4BE7D200453BC CRC64;
     MSEKAGSQSG GSPEASGVTV SDVQELIRRK EEIEAQIKAN YEVLESQKGI GMNEPLVDCE
     GYPRADVDLY QVRTARHNIV CLQNDHKAVM KQVEDALHQL HARDKEKQAR DLAEAHREAL
     SRDQSQGLSP AQAFAKVNSI SPGSPASIAG LQVDDEILEF GSVNTQNFQS LQNIGSVVQH
     SEGKPLNVTV MRRGEKHQLR LVPTRWAGKG LLGCNIIPLQ R