ID   PSMD9_CAEEL             Reviewed;         197 AA.
AC   Q10920; G8JXY6; Q95QR4;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2003, sequence version 2.
DT   03-AUG-2022, entry version 147.
DE   RecName: Full=Probable 26S proteasome non-ATPase regulatory subunit 9;
GN   Name=psmd-9; ORFNames=C44B7.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Acts as a chaperone during the assembly of the 26S
CC       proteasome, specifically of the base subcomplex of the 19S regulatory
CC       complex (RC). {ECO:0000250}.
CC   -!- INTERACTION:
CC       Q10920; O76371: rpt-5; NbExp=3; IntAct=EBI-317193, EBI-317201;
CC   -!- SIMILARITY: Belongs to the proteasome subunit p27 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FO080139; CCD61554.1; -; Genomic_DNA.
DR   PIR; T15289; T15289.
DR   RefSeq; NP_001293499.1; NM_001306570.1.
DR   AlphaFoldDB; Q10920; -.
DR   SMR; Q10920; -.
DR   IntAct; Q10920; 6.
DR   STRING; 6239.C44B7.1; -.
DR   EPD; Q10920; -.
DR   PaxDb; Q10920; -.
DR   PeptideAtlas; Q10920; -.
DR   EnsemblMetazoa; C44B7.1.1; C44B7.1.1; WBGene00016623.
DR   GeneID; 24104302; -.
DR   UCSC; C44B7.1.2; c. elegans.
DR   CTD; 24104302; -.
DR   WormBase; C44B7.1; CE25810; WBGene00016623; psmd-9.
DR   eggNOG; KOG3129; Eukaryota.
DR   GeneTree; ENSGT00390000004147; -.
DR   HOGENOM; CLU_073146_2_1_1; -.
DR   InParanoid; Q10920; -.
DR   OMA; GCNIVPL; -.
DR   OrthoDB; 1405146at2759; -.
DR   PhylomeDB; Q10920; -.
DR   Reactome; R-CEL-1234176; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha.
DR   Reactome; R-CEL-1236978; Cross-presentation of soluble exogenous antigens (endosomes).
DR   Reactome; R-CEL-187577; SCF(Skp2)-mediated degradation of p27/p21.
DR   Reactome; R-CEL-195253; Degradation of beta-catenin by the destruction complex.
DR   Reactome; R-CEL-349425; Autodegradation of the E3 ubiquitin ligase COP1.
DR   Reactome; R-CEL-350562; Regulation of ornithine decarboxylase (ODC).
DR   Reactome; R-CEL-382556; ABC-family proteins mediated transport.
DR   Reactome; R-CEL-4608870; Asymmetric localization of PCP proteins.
DR   Reactome; R-CEL-4641258; Degradation of DVL.
DR   Reactome; R-CEL-5632684; Hedgehog 'on' state.
DR   Reactome; R-CEL-5689603; UCH proteinases.
DR   Reactome; R-CEL-5689880; Ub-specific processing proteases.
DR   Reactome; R-CEL-68949; Orc1 removal from chromatin.
DR   Reactome; R-CEL-69017; CDK-mediated phosphorylation and removal of Cdc6.
DR   Reactome; R-CEL-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis.
DR   Reactome; R-CEL-8939902; Regulation of RUNX2 expression and activity.
DR   Reactome; R-CEL-8941858; Regulation of RUNX3 expression and activity.
DR   Reactome; R-CEL-8948751; Regulation of PTEN stability and activity.
DR   Reactome; R-CEL-8951664; Neddylation.
DR   Reactome; R-CEL-9755511; KEAP1-NFE2L2 pathway.
DR   Reactome; R-CEL-9762114; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2.
DR   Reactome; R-CEL-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR   PRO; PR:Q10920; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00016623; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0070682; P:proteasome regulatory particle assembly; IBA:GO_Central.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR040815; Nas2_N.
DR   InterPro; IPR041489; PDZ_6.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR035269; PSMD9.
DR   PANTHER; PTHR12651; PTHR12651; 1.
DR   Pfam; PF18265; Nas2_N; 1.
DR   Pfam; PF17820; PDZ_6; 1.
DR   SUPFAM; SSF50156; SSF50156; 1.
PE   1: Evidence at protein level;
KW   Chaperone; Reference proteome.
FT   CHAIN           1..197
FT                   /note="Probable 26S proteasome non-ATPase regulatory
FT                   subunit 9"
FT                   /id="PRO_0000173855"
FT   DOMAIN          75..166
FT                   /note="PDZ"
SQ   SEQUENCE   197 AA;  22133 MW;  E6693CE5141FE0E2 CRC64;
     MDHHSKAKEL LQQRDELDGK IKELMLVLET NNSTMDSPLL DAEGYPLNTI DVYAVRHARH
     DLICLRNDRA ALTEKIVVEM ENENKEVSGQ TATSEEKPVH RTSNEPFVKI SSVVELSPAD
     IGGFRKDDLI IQYGNLHHGN FNDMQEVAQI TKQSEDKIIR VTVIRENRPV RLEICPKKWS
     GPGLLGCNIV PISGANV