ID   PSMG1_XENLA             Reviewed;         288 AA.
AC   Q05AX3;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=Proteasome assembly chaperone 1;
GN   Name=psmg1 {ECO:0000250|UniProtKB:O95456};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1] {ECO:0000312|EMBL:AAI23193.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Fat body {ECO:0000312|EMBL:AAI23193.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Chaperone protein which promotes assembly of the 20S
CC       proteasome as part of a heterodimer with psmg2. {ECO:0000250}.
CC   -!- SUBUNIT: Forms a heterodimer with psmg2. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:O95456}.
CC       Endoplasmic reticulum {ECO:0000250|UniProtKB:O95456}.
CC   -!- PTM: Degraded by the proteasome upon completion of 20S proteasome
CC       maturation. {ECO:0000250|UniProtKB:O95456}.
CC   -!- SIMILARITY: Belongs to the PSMG1 family. {ECO:0000255}.
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DR   EMBL; BC123192; AAI23193.1; -; mRNA.
DR   RefSeq; NP_001090485.1; NM_001097016.1.
DR   AlphaFoldDB; Q05AX3; -.
DR   SMR; Q05AX3; -.
DR   DNASU; 779398; -.
DR   GeneID; 779398; -.
DR   KEGG; xla:779398; -.
DR   CTD; 779398; -.
DR   Xenbase; XB-GENE-866332; psmg1.L.
DR   OrthoDB; 1232038at2759; -.
DR   Proteomes; UP000186698; Chromosome 2L.
DR   Bgee; 779398; Expressed in oocyte and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.
DR   GO; GO:0051131; P:chaperone-mediated protein complex assembly; ISS:UniProtKB.
DR   GO; GO:0043248; P:proteasome assembly; IEA:InterPro.
DR   InterPro; IPR016565; Proteasome_assmbl_chp_1.
DR   PANTHER; PTHR15069; PTHR15069; 1.
DR   Pfam; PF16094; PAC1; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Cytoplasm; Endoplasmic reticulum; Reference proteome.
FT   CHAIN           1..288
FT                   /note="Proteasome assembly chaperone 1"
FT                   /id="PRO_0000322549"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..33
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   288 AA;  32147 MW;  92A210FD9E0EDC08 CRC64;
     MATFFGEVQS VFSRAVDEEE EDEDDDEEEE EDREIIAELE RKREVRVTWN PELTAAIESS
     PGKRLPCSSV ILSVGDNATG FVSSYILSSG SWEVAGSVTL WNERCRDCNV RKDFLPAPSS
     CTFYRSITDP TVLLCQCNCH VAEDQLFQWC EKVFGSLEKS SLKVTVLSTC PVSEYKTPES
     TYSLPVPFLK ALRTSEYREE VPCPLLEQPN IVDGLPAAVL SHCQVLGIPA VFYQCYTDIS
     KLDSVTIKAF RPLLSSGSLS RLAADSANIQ ETLRKTVKLN EIQSNLYI