PSPC_ECOLI
ID PSPC_ECOLI Reviewed; 119 AA.
AC P0AFN2; P23855;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Phage shock protein C;
GN Name=pspC; OrderedLocusNames=b1306, JW1299;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, AND INDUCTION.
RC STRAIN=K12;
RX PubMed=1712397; DOI=10.1016/0022-2836(91)90379-k;
RA Brissette J.L., Weiner L., Ripmaster T.L., Model P.;
RT "Characterization and sequence of the Escherichia coli stress-induced psp
RT operon.";
RL J. Mol. Biol. 220:35-48(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP INTERACTION WITH PSPA.
RC STRAIN=K12;
RX PubMed=12562786; DOI=10.1128/jb.185.4.1174-1180.2003;
RA Adams H., Teertstra W., Demmers J., Boesten R., Tommassen J.;
RT "Interactions between phage-shock proteins in Escherichia coli.";
RL J. Bacteriol. 185:1174-1180(2003).
CC -!- FUNCTION: The phage shock protein (psp) operon (pspABCDE) may play a
CC significant role in the competition for survival under nutrient- or
CC energy-limited conditions. PspC is involved in transcription
CC regulation. {ECO:0000269|PubMed:1712397}.
CC -!- SUBUNIT: Interacts with PspA. {ECO:0000269|PubMed:12562786}.
CC -!- INTERACTION:
CC P0AFN2; P0AEC3: arcB; NbExp=3; IntAct=EBI-1134561, EBI-557109;
CC P0AFN2; P0AFM6: pspA; NbExp=9; IntAct=EBI-1134561, EBI-1123459;
CC P0AFN2; P0AFM9: pspB; NbExp=5; IntAct=EBI-1134561, EBI-6408513;
CC P0AFN2; P32696: pspG; NbExp=3; IntAct=EBI-1134561, EBI-25641301;
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Single-pass
CC membrane protein {ECO:0000305}.
CC -!- INDUCTION: By heat, ethanol, osmotic shock and infection by filamentous
CC bacteriophages. {ECO:0000269|PubMed:1712397}.
CC -!- SIMILARITY: Belongs to the phageshock PspC family. {ECO:0000305}.
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DR EMBL; X57560; CAA40791.1; -; Genomic_DNA.
DR EMBL; U00096; AAC74388.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA14875.1; -; Genomic_DNA.
DR PIR; S17123; S17123.
DR RefSeq; NP_415822.1; NC_000913.3.
DR RefSeq; WP_000907387.1; NZ_STEB01000005.1.
DR AlphaFoldDB; P0AFN2; -.
DR SMR; P0AFN2; -.
DR BioGRID; 4263228; 429.
DR ComplexPortal; CPX-5892; PspBC inner membrane stress response complex.
DR DIP; DIP-48215N; -.
DR IntAct; P0AFN2; 6.
DR STRING; 511145.b1306; -.
DR jPOST; P0AFN2; -.
DR PaxDb; P0AFN2; -.
DR PRIDE; P0AFN2; -.
DR EnsemblBacteria; AAC74388; AAC74388; b1306.
DR EnsemblBacteria; BAA14875; BAA14875; BAA14875.
DR GeneID; 66674866; -.
DR GeneID; 945499; -.
DR KEGG; ecj:JW1299; -.
DR KEGG; eco:b1306; -.
DR PATRIC; fig|1411691.4.peg.973; -.
DR EchoBASE; EB0771; -.
DR eggNOG; COG1983; Bacteria.
DR HOGENOM; CLU_137949_2_0_6; -.
DR OMA; MEAYVTS; -.
DR PhylomeDB; P0AFN2; -.
DR BioCyc; EcoCyc:EG10778-MON; -.
DR PRO; PR:P0AFN2; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0010557; P:positive regulation of macromolecule biosynthetic process; IMP:EcoCyc.
DR GO; GO:0080135; P:regulation of cellular response to stress; IC:ComplexPortal.
DR InterPro; IPR014320; Phageshock_PspC.
DR InterPro; IPR007168; Phageshock_PspC_N.
DR Pfam; PF04024; PspC; 1.
DR TIGRFAMs; TIGR02978; phageshock_pspC; 1.
PE 1: Evidence at protein level;
KW Activator; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Stress response; Transcription;
KW Transcription regulation; Transmembrane; Transmembrane helix.
FT CHAIN 1..119
FT /note="Phage shock protein C"
FT /id="PRO_0000097074"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 119 AA; 13517 MW; F63BED3EC5EDEE90 CRC64;
MAGINLNKKL WRIPQQGMVR GVCAGIANYF DVPVKLVRIL VVLSIFFGLA LFTLVAYIIL
SFALDPMPDN MAFGEQLPSS SELLDEVDRE LAASETRLRE MERYVTSDTF TLRSRFRQL
